Glycolysis and glycolytic capacity in response to pre-exposure to lactone- and acid-form simvastatin were measured by detecting extracellular acidification rate (ECAR) in primary human myoblasts with Seahorse analyzer. Data (in mpH/min/20,000 cells) are expressed as mean ± s.e.m. from six men. ***P < 0.001 vs respective control, one-way ANOVA with repeated measurements, Sidak’s post hoc test.
Citation: Endocrine Connections 11, 7; 10.1530/EC-20-0444e