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Nadia Sawicka-Gutaj Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Ariadna Zybek-Kocik Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Michał Kloska Lehigh Valley Health Network, Department of Medicine, Lehigh Valley Hospital – Cedar Crest, Allentown, USA

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Paulina Ziółkowska Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Agata Czarnywojtek Department of Pharmacology, Poznan University of Medical Sciences, Poznan, Poland

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Jerzy Sowiński Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Dorota Mańkowska-Wierzbicka Department of Gastroenterology, Internal Medicine, Metabolic Diseases and Dietetics, Poznan University of Medical Sciences, Poznan, Poland

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Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Introduction The adipose tissue is a well-established source of multiple circulating peptides that are responsible for various metabolic effects ( 1 ). Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) has been recently recognized as an

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Nese Cinar Department of Endocrinology and Metabolism, Hacettepe University School of Medicine, 06100 Sihhiye, Ankara, Turkey

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Alper Gurlek Department of Endocrinology and Metabolism, Hacettepe University School of Medicine, 06100 Sihhiye, Ankara, Turkey

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endocrine, paracrine, and autocrine hormones; cytokines; and growth factors which influence local adipose tissue and different organs/tissues. These include CNS, liver, pancreas, and the skeletal muscles. Leptin, adiponectin (ADP), vaspin, visfatin

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Katarzyna Wyskida Health Promotion and Obesity Management Unit, Department of Pathophysiology, Medical Faculty of Silesia in Katowice, Medical University of Silesia, Katowice, Poland

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Grzegorz Franik Department of Gynecological Endocrinology, Medical Faculty of Silesia in Katowice, Medical University of Silesia, Katowice, Poland

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Tomasz Wikarek Department of Gynecology, Medical Faculty of Silesia in Katowice, Medical University of Silesia, Katowice, Poland

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Aleksander Owczarek Department of Statistics, School of Pharmacy with the Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia, Katowice, Poland

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Alham Delroba Health Promotion and Obesity Management Unit, Department of Pathophysiology, Medical Faculty of Silesia in Katowice, Medical University of Silesia, Katowice, Poland

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Jerzy Chudek Pathophysiology Unit, Department of Pathophysiology, Medical Faculty of Silesia in Katowice, Medical University of Silesia, Katowice, Poland

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Jerzy Sikora Department of Perinatology and Gynecology, Medical University of Silesia, Katowice, Poland

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Magdalena Olszanecka-Glinianowicz Health Promotion and Obesity Management Unit, Department of Pathophysiology, Medical Faculty of Silesia in Katowice, Medical University of Silesia, Katowice, Poland

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study cohorts, and in some cases, the inclusion of overweight women. The lack of TNF-alpha changes during the menstrual cycle has been observed in a single study ( 20 ), while plasma concentrations of omentin, visfatin/NAMPT, vaspin, apelin-36, RBP4 and

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Cheryl M Isherwood Section of Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom

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M Denise Robertson Section of Metabolic Medicine, Food and Macronutrients, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom

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Debra J Skene Section of Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom

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Jonathan D Johnston Section of Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom

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), glucagon, ghrelin, leptin, resistin, visfatin and plasminogen activator inhibitor-1 (PAI-1)) were measured with a multiplex immunoassay (Bio-Plex Pro™ Human Diabetes Assay, Bio-Rad Laboratories Ltd) requiring 50 µL of plasma per sample. The BioPlex software

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Davoud Jafari-Gharabaghlou Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

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Mostafa Vaghari-Tabari Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

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Hajar Oghbaei Department of Physiology, Tabriz University of Medical Sciences, Tabriz, Iran

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Laura Lotz Department of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen–Nürnberg, Erlangen, Germany

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Reza Zarezadeh Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

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Yeganeh Rastgar Rezaei Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran

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Mahnaz Ranjkesh Medical Radiation Science Research Group (MRSRG), Tabriz University of Medical Sciences, Tabriz, Iran

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Mohammad Nouri Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran

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Amir Fattahi Department of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen–Nürnberg, Erlangen, Germany
Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

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Saba Nikanfar Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

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Ralf Dittrich Department of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen–Nürnberg, Erlangen, Germany

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, adiponectin, apelin, chemerin, progranulin, retinol-binding protein 4 (RBP4), and visfatin have been investigated ( 7 , 24 , 25 , 26 , 27 ). In the following sections, we explain the adipokines and their possible role in embryo implantation. Moreover, the

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Huguette S Brink Department of Endocrinology, Maasstad Hospital, Rotterdam, The Netherlands

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Aart Jan van der Lely Department of Endocrinology, Erasmus University MC, Rotterdam, The Netherlands

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Joke van der Linden Department of Endocrinology, Maasstad Hospital, Rotterdam, The Netherlands

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). It drives the expression and production of proinflammatory (TNF-alpha and IL-6) and anti-inflammatory cytokines or adipokines (adiponectin, leptin and visfatin) ( 28 ). Adipokines have a clear regulatory role in metabolism, including modifying insulin

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Aline Stangherlin Martins Neurofibromatosis Outpatient Reference Center, Department of Nutrition, Federal University of Minas Gerais, Department of Medical Clinic, Federal University of Minas Gerais, Department of Preventive and Social Medicine, Federal University of Minas Gerais, Department of Internal Medicine, Federal University of Minas Gerais, The Neurofibromatosis Institute, Federal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, Brazil

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Ann Kristine Jansen Neurofibromatosis Outpatient Reference Center, Department of Nutrition, Federal University of Minas Gerais, Department of Medical Clinic, Federal University of Minas Gerais, Department of Preventive and Social Medicine, Federal University of Minas Gerais, Department of Internal Medicine, Federal University of Minas Gerais, The Neurofibromatosis Institute, Federal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, Brazil

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Luiz Oswaldo Carneiro Rodrigues Neurofibromatosis Outpatient Reference Center, Department of Nutrition, Federal University of Minas Gerais, Department of Medical Clinic, Federal University of Minas Gerais, Department of Preventive and Social Medicine, Federal University of Minas Gerais, Department of Internal Medicine, Federal University of Minas Gerais, The Neurofibromatosis Institute, Federal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, Brazil

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Camila Maria Matos Neurofibromatosis Outpatient Reference Center, Department of Nutrition, Federal University of Minas Gerais, Department of Medical Clinic, Federal University of Minas Gerais, Department of Preventive and Social Medicine, Federal University of Minas Gerais, Department of Internal Medicine, Federal University of Minas Gerais, The Neurofibromatosis Institute, Federal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, Brazil

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Marcio Leandro Ribeiro Souza Neurofibromatosis Outpatient Reference Center, Department of Nutrition, Federal University of Minas Gerais, Department of Medical Clinic, Federal University of Minas Gerais, Department of Preventive and Social Medicine, Federal University of Minas Gerais, Department of Internal Medicine, Federal University of Minas Gerais, The Neurofibromatosis Institute, Federal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, Brazil

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Juliana Ferreira de Souza Neurofibromatosis Outpatient Reference Center, Department of Nutrition, Federal University of Minas Gerais, Department of Medical Clinic, Federal University of Minas Gerais, Department of Preventive and Social Medicine, Federal University of Minas Gerais, Department of Internal Medicine, Federal University of Minas Gerais, The Neurofibromatosis Institute, Federal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, Brazil

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Maria de Fátima Haueisen Sander Diniz Neurofibromatosis Outpatient Reference Center, Department of Nutrition, Federal University of Minas Gerais, Department of Medical Clinic, Federal University of Minas Gerais, Department of Preventive and Social Medicine, Federal University of Minas Gerais, Department of Internal Medicine, Federal University of Minas Gerais, The Neurofibromatosis Institute, Federal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, Brazil

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Sandhi Maria Barreto Neurofibromatosis Outpatient Reference Center, Department of Nutrition, Federal University of Minas Gerais, Department of Medical Clinic, Federal University of Minas Gerais, Department of Preventive and Social Medicine, Federal University of Minas Gerais, Department of Internal Medicine, Federal University of Minas Gerais, The Neurofibromatosis Institute, Federal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, Brazil

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Leonardo Mauricio Diniz Neurofibromatosis Outpatient Reference Center, Department of Nutrition, Federal University of Minas Gerais, Department of Medical Clinic, Federal University of Minas Gerais, Department of Preventive and Social Medicine, Federal University of Minas Gerais, Department of Internal Medicine, Federal University of Minas Gerais, The Neurofibromatosis Institute, Federal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, Brazil

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Nilton Alves de Rezende Neurofibromatosis Outpatient Reference Center, Department of Nutrition, Federal University of Minas Gerais, Department of Medical Clinic, Federal University of Minas Gerais, Department of Preventive and Social Medicine, Federal University of Minas Gerais, Department of Internal Medicine, Federal University of Minas Gerais, The Neurofibromatosis Institute, Federal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, Brazil
Neurofibromatosis Outpatient Reference Center, Department of Nutrition, Federal University of Minas Gerais, Department of Medical Clinic, Federal University of Minas Gerais, Department of Preventive and Social Medicine, Federal University of Minas Gerais, Department of Internal Medicine, Federal University of Minas Gerais, The Neurofibromatosis Institute, Federal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, Brazil

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Vincent Michael Riccardi Neurofibromatosis Outpatient Reference Center, Department of Nutrition, Federal University of Minas Gerais, Department of Medical Clinic, Federal University of Minas Gerais, Department of Preventive and Social Medicine, Federal University of Minas Gerais, Department of Internal Medicine, Federal University of Minas Gerais, The Neurofibromatosis Institute, Federal University of Minas Gerais, Alameda Álvaro Celso 55, Belo Horizonte, Minas Gerais, Brazil

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adipocytokines (leptin, visfatin, resistin, and adiponectin). Adipocytokines are bioactive proteins secreted by adipose tissue (30, 31) , which influence such physiologic processes as control of food intake, energy homeostasis, angiogenesis, vascular protection

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Shilpa Lingaiah Department of Obstetrics and Gynaecology, PEDEGO Research Unit, Medical Research Centre, University of Oulu and Oulu University Hospital, Oulu, Finland

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Laure Morin-Papunen Department of Obstetrics and Gynaecology, PEDEGO Research Unit, Medical Research Centre, University of Oulu and Oulu University Hospital, Oulu, Finland

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Terhi Piltonen Department of Obstetrics and Gynaecology, PEDEGO Research Unit, Medical Research Centre, University of Oulu and Oulu University Hospital, Oulu, Finland

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Inger Sundström-Poromaa Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden

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Elisabet Stener-Victorin Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden

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Juha S Tapanainen Department of Obstetrics and Gynaecology, PEDEGO Research Unit, Medical Research Centre, University of Oulu and Oulu University Hospital, Oulu, Finland
Department of Obstetrics and Gynaecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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levels of visfatin and retinol-binding protein 4 (RBP4) associated with body mass, metabolic and hormonal disturbances in women with polycystic ovary syndrome? European Journal of Obstetrics, Gynecology, and Reproductive Biology 2012 162 55 – 61

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Qing Zhou Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children’s Hospital, Fuzhou, China

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Li Yong Zhang Department of Thyroid Surgery, Minimal Invasive Center, Fujian Medical University Union Hospital, Fuzhou, China

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Mei Feng Dai Department of Clinical Lab, Fujian Maternity and Child Health Hospital, Fuzhou, China

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Zhen Li Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children’s Hospital, Fuzhou, China

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Chao Chun Zou Department of Endocrinology, The Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, China

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Hui Liu Department of Endocrinology, Fujian Maternity and Child Health Hospital, Fujian Children’s Hospital, Fuzhou, China

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insulin resistance in 3T3-L1 cells through the PPARγ . Molecular and Cellular Biochemistry 2022 477 1107 – 1112 . ( https://doi.org/10.1007/s11010-022-04367-7 ) 16 Wu MH Tsai CH Huang YL Fong YC & Tang CH . Visfatin promotes IL-6 and TNF

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Ningning Gong Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China
Department of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu, China

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Cuixia Gao Department of Ultrasonic Diagnosis, Gansu Provincial Hospital, Lanzhou, China

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Xuedi Chen Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China

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Yu Wang Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China

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Limin Tian Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China

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: http://press.endocrine.org/doi/abs/10.1210/endo-meetings.2013.THPTA.6.SUN-455 ) 44 Guzel S Seven A Guzel EC Buyuk B Celebi A Aydemir B . Visfatin, leptin, and TNF-alpha: interrelated adipokines in insulin-resistant clinical and subclinical

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