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Lars Peter Sørensen, Tina Parkner, Esben Søndergaard, Bo Martin Bibby, Holger Jon Møller and Søren Nielsen

demonstrated that expansion of visceral adipose tissue (VAT) rather than subcutaneous adipose tissue (SAT) depots is critical for the development of obesity-associated insulin resistance, and that, at least in overweight/obese subjects, expansion of SAT depots

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Alessandra Gambineri and Carla Pelusi

-to-male transsexuals demonstrated that testosterone-ester administration at the dose of 250 mg i.m. every 2 weeks produced a significant increase in visceral adipose tissue and a decrease in insulin sensitivity evaluated by the euglycemic–hyperinsulinemic clamp ( 19

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Trevor Lewis, Eva Zeisig and Jamie E Gaida

preferentially increases lipoprotein lipase activity in visceral adipose tissue, which increases uptake of triglycerides and fatty acids into adipocytes leading to increased visceral adiposity ( 20 ). Furthermore, glucocorticoid receptor alpha is more highly

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Ningning Gong, Cuixia Gao, Xuedi Chen, Yu Wang and Limin Tian

preadipocytes by affecting the function of the TSH receptor (TSHR) protein ( 7 ). Visceral adipose tissue (VAT) is the main adipose tissue that produces diverse adipokines, and VAT volume is increased in patients with sHT compared with VAT volume in normal

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Sandrine Visentin, Gérard Michel, Claire Oudin, Béatrice Cousin, Bénédicte Gaborit, Inès Abdesselam, Marie Maraninchi, Marion Nowicki, René Valéro, Maxime Guye, Monique Bernard, Pascal Auquier, Hervé Chambost, Marie-Christine Alessi and Sophie Béliard

0.12 sSAT (cm 2 , mean ±  s.d. ) 265 ± 94 196 ± 96 0.15 106 ± 42 111 ± 62 0.76 178 ± 107 165 ± 92 0.79 AT, adipose tissue; intra-abdominal AT = dSAT+VAT; dSAT, deep SAT; SAT, subcutaneous adipose tissue; sSAT

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Hong-Fa Yan, Zhao-Yu Liu, Zhi-Ang Guan and Chuang Guo

, 36 ). It has been reported that, in murine models, iron-enriched diets decrease adipocyte insulin sensitivity and are associated with visceral adipose tissue hyperplasia and hypertrophy; however, iron-restricted diets lead to opposite effects ( 16

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Michaela Keuper

adipocytes . Diabetes 2004 53 . ( ) 15111498 40 Curat CA Wegner V Sengenès C Miranville A Tonus C Busse R Bouloumié A . Macrophages in human visceral adipose tissue: increased accumulation in

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Nese Cinar and Alper Gurlek

in visceral (epididymal) and subcutaneous (inguinal) adipose tissues, while ADP mRNA expression was downregulated by T 3 in the subcutaneous adipose tissue, but not in the visceral adipose tissue (VAT). The authors suggest that ADP mRNA response to T

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Antonia Ertelt, Ann-Kristin Barton, Robert R Schmitz and Heidrun Gehlen

localizations of adipose tissue, lipogenesis differs at various fat depots (30, 31, 32) . There are also differences in gene expression in visceral and subcutaneous fat in humans; however, isolated and cultured human preadipocytes are still capable of their

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Julia H Goedecke, Mehreen Tootla and Dheshnie Keswell

comprises both visceral (VAT) and subcutaneous adipose tissue (SAT), is commonly associated with increased cardiometabolic risk, whereas lower-body gluteo-femoral fat accumulation may be protective ( 4 , 5 ). Within adipose tissue, aromatase ( CYP19A1