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Katrine M Lauritsen Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark

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Jens Hohwü Voigt Steno Diabetes Center Aarhus, Aarhus, Denmark

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Steen Bønløkke Pedersen Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Troels K Hansen Steno Diabetes Center Aarhus, Aarhus, Denmark

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Niels Møller Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Niels Jessen Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Biomedicine, Aarhus University, Aarhus, Denmark

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Lars C Gormsen Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark

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Esben Søndergaard Steno Diabetes Center Aarhus, Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark

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C-palmitate uptake was calculated as previously suggested by Bucci et al . ( 17 ). Figure 2 Drawing of VOIs on the fused PET/CT images. (A) s.c. adipose tissue VOIs were placed in the right upper abdomen, whereas the visceral adipose tissue

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-21-0558
Volume/Issue:
Volume 11: Issue 4
Open access
Lars Peter Sørensen
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Tina Parkner Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark

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Esben Søndergaard
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Bo Martin Bibby Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark

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Holger Jon Møller Department of Endocrinology and Internal Medicine, Department of Clinical Biochemistry, Department of Biostatistics, Department of Clinical Biochemistry, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus C, Denmark

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Søren Nielsen
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demonstrated that expansion of visceral adipose tissue (VAT) rather than subcutaneous adipose tissue (SAT) depots is critical for the development of obesity-associated insulin resistance, and that, at least in overweight/obese subjects, expansion of SAT depots

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-14-0107
Volume/Issue:
Volume 4: Issue 1
Open access
Alessandra Gambineri Endocrinology Unit, Department of Medical and Surgical Sciences, St Orsola-Malpighi Hospital, Alma Mater University of Bologna, Bologna, Italy

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Carla Pelusi Endocrinology Unit, Department of Medical and Surgical Sciences, St Orsola-Malpighi Hospital, Alma Mater University of Bologna, Bologna, Italy

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-to-male transsexuals demonstrated that testosterone-ester administration at the dose of 250 mg i.m. every 2 weeks produced a significant increase in visceral adipose tissue and a decrease in insulin sensitivity evaluated by the euglycemic–hyperinsulinemic clamp ( 19

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0450
Volume/Issue:
Volume 8: Issue 1
Open access
Trevor Lewis Physiotherapy Department, Aintree University Hospital NHS Foundation Trust, Liverpool, UK

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Eva Zeisig Department of Surgical and Perioperative Sciences, Umeå Univerisity, Umeå, Sweden

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Jamie E Gaida University of Canberra Research Institute for Sport and Exercise (UCRISE), Canberra, Australian Capital Territory, Australia

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preferentially increases lipoprotein lipase activity in visceral adipose tissue, which increases uptake of triglycerides and fatty acids into adipocytes leading to increased visceral adiposity ( 20 ). Furthermore, glucocorticoid receptor alpha is more highly

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-19-0555
Volume/Issue:
Volume 9: Issue 3
Open access
Ningning Gong Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China
Department of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu, China

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Cuixia Gao Department of Ultrasonic Diagnosis, Gansu Provincial Hospital, Lanzhou, China

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Xuedi Chen Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China

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Yu Wang Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China

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Limin Tian Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China

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preadipocytes by affecting the function of the TSH receptor (TSHR) protein ( 7 ). Visceral adipose tissue (VAT) is the main adipose tissue that produces diverse adipokines, and VAT volume is increased in patients with sHT compared with VAT volume in normal

Article Type:
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DOI:
https://doi.org/10.1530/EC-18-0007
Volume/Issue:
Volume 7: Issue 2
Open access
Fabyan Esberard de Lima Beltrão Lauro Wanderley University Hospital, Federal University of Paraíba, João Pessoa, Paraíba, Brazil
Postgraduate Program in Nutritional Sciences, Department of Nutrition, Center for Health Sciences, Federal University of Paraíba, João Pessoa, Paraíba, Brazil
University Centre of João Pessoa (UNIPE), João Pessoa, Paraíba, Brazil

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Daniele Carvalhal de Almeida Beltrão University Centre of João Pessoa (UNIPE), João Pessoa, Paraíba, Brazil
Postgraduate Program in Cognitive Neuroscience and Behavior, Center for Health Sciences, Federal University of Paraíba, João Pessoa, Paraíba, Brazil

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Giulia Carvalhal Center for Biological and Health Sciences, Federal University of Campina Grande, Campina Grande, Paraíba, Brazil

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Fabyo Napoleão de Lima Beltrão Department of Medicine, Faculty of Medical Sciences, João Pessoa, Brazil

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Igor Motta de Aquino Metropolitan Hospital Dom José Maria Pires, Santa Rita, Paraíba, Brazil

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Thaíse da Silva Brito New Hope Medical School – FAMENE, João Pessoa, Paraíba, Brazil

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Barbara Costa Paulino Postgraduate Program in Nutritional Sciences, Department of Nutrition, Center for Health Sciences, Federal University of Paraíba, João Pessoa, Paraíba, Brazil

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Elisa Aires Postgraduate Program in Interactive Processes of Organs and Systems, Health & Science Institute, Federal University of Bahia, Salvador, Bahia, Brazil

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Diana Viegas Internal Medicine Department, rede UniFTC, Salvador, Bahia, Brazil

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Fabio Hecht The Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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Bruno Halpern Weight Control Centre, Hospital 9 de Julho, São Paulo, São Paulo, Brazil

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Liana Clebia De Morais Pordeus Postgraduate Program in Cognitive Neuroscience and Behavior, Center for Health Sciences, Federal University of Paraíba, João Pessoa, Paraíba, Brazil

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Maria da Conceição Rodrigues Gonçalves Postgraduate Program in Nutritional Sciences, Department of Nutrition, Center for Health Sciences, Federal University of Paraíba, João Pessoa, Paraíba, Brazil

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Helton Estrela Ramos Postgraduate Program in Interactive Processes of Organs and Systems, Health & Science Institute, Federal University of Bahia, Salvador, Bahia, Brazil
Department of Biorregulation, Health Sciences Institute, Federal University of Bahia, Bahia, Brazil
Postgraduate Program in Medicine and Health, Medical School of Medicine, Federal University of Bahia, Salvador, Bahia, Brazil

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. The technical parameters of CT acquisition were adjusted according to the clinical problem under investigation and patient body size. The assessment of the visceral adipose tissue (VAT) area, s.c. adipose tissue (SAT) area, and muscle area (MA) with

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-22-0290
Volume/Issue:
Volume 11: Issue 10
Open access
Melony C Fortuin-de Smidt Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Cape Town, South Africa
Non-Communicable Diseases Research Unit, South African Medical Council, Tygerberg, South Africa

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Amy E Mendham Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Cape Town, South Africa
Non-Communicable Diseases Research Unit, South African Medical Council, Tygerberg, South Africa

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Jon Hauksson Department of Radiation Sciences, Radiation Physics and Biomedical Engineering, Umea University, Umea, Sweden

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Ali Alhamud Department of Human Biology, MRC/UCT Medical Imaging Research Unit, University of Cape Town, Cape Town, South Africa
The Modern Pioneer Center and ArSMRM for MRI Training and Development, Tripoli, Libya

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Darko Stefanovski Department of Clinical Studies, New Bolton Centre, University of Pennsylvania School of Veterinary Medicine, Kennett Square, Pennsylvania, USA

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Olah Hakim Department of Diabetes, Faculty of Life Sciences and Medicine, School of Life Course Sciences, King’s College London, London, UK

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Jeroen Swart Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Cape Town, South Africa

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Louise M Goff Department of Diabetes, Faculty of Life Sciences and Medicine, School of Life Course Sciences, King’s College London, London, UK

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Steven E Kahn Division of Metabolism, Endocrinology and Nutrition, Department of Medicine, Veterans Affairs Puget Sound Health Care System, University of Washington, Seattle, Washington, USA

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Tommy Olsson Department of Public Health and Clinical Medicine, Umea University, Umea, Sweden

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Julia H Goedecke Division of Exercise Science and Sports Medicine, Department of Human Biology, University of Cape Town, Cape Town, South Africa
Non-Communicable Diseases Research Unit, South African Medical Council, Tygerberg, South Africa

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, soleus intra-myocellular fat; TEMCL, tibialis anterior extra-myocellular fat; TIMCL, tibialis anterior intra-myocellular fat; VAT, visceral adipose tissue. adipose tissue; SIMCL, soleus intra-myocellular fat; SEMCL, soleus extra-myocellular fat; TIMCL

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0153
Volume/Issue:
Volume 10: Issue 5
Open access
Yee-Ming M Cheung Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia
Department of Endocrinology, Austin Health, Melbourne, Australia
Division of Endocrinology, Diabetes and Metabolism, Northwell, Great Neck, New York, USA

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Rudolf Hoermann Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia

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Karen Van Department of Endocrinology, Austin Health, Melbourne, Australia

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Damian Wu Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia

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Jenny Healy Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia

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Bella Halim Department of Endocrinology, Austin Health, Melbourne, Australia

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Manjri Raval Department of Endocrinology, Austin Health, Melbourne, Australia

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Maria McGill Department of Radiology, Austin Health, Melbourne, Australia

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Ali Al-Fiadh Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia
Department of Cardiology, Austin Health, Melbourne Australia

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Michael Chao Olivia Newton-John Cancer Research and Wellness Centre, Austin Health, Melbourne, Australia

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Shane White Olivia Newton-John Cancer Research and Wellness Centre, Austin Health, Melbourne, Australia

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Belinda Yeo Olivia Newton-John Cancer Research and Wellness Centre, Austin Health, Melbourne, Australia
Olivia Newton-John Cancer Research Institute, Austin Health, Melbourne, Australia

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Jeffrey D Zajac Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia
Department of Endocrinology, Austin Health, Melbourne, Australia

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Mathis Grossmann Department of Medicine, The University of Melbourne, Austin Health, Melbourne, Australia
Department of Endocrinology, Austin Health, Melbourne, Australia

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oestrogen states ( 18 , 19 ) have been associated with increases in visceral adipose tissue (VAT), the changes which are often mitigated when oestradiol is added back ( 18 , 19 ). As a bidirectional relationship exists between excess VAT and the many

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Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-23-0076
Volume/Issue:
Volume 12: Issue 10
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Sandrine Visentin Department of Pediatric Hematology and Oncology, AP-HM, Timone Enfants Hospital, Marseille, France
Aix Marseille University, INSERM, INRA, C2VN, Marseille, France

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Gérard Michel Department of Pediatric Hematology and Oncology, AP-HM, Timone Enfants Hospital, Marseille, France
Research Unit EA 3279 and Department of Public Health, Aix-Marseille University, Marseille, France

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Claire Oudin Department of Pediatric Hematology and Oncology, AP-HM, Timone Enfants Hospital, Marseille, France
Research Unit EA 3279 and Department of Public Health, Aix-Marseille University, Marseille, France

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Béatrice Cousin STROMALab, Université de Toulouse, CNRS ERL5311, EFS, INP-ENVT, INSERM U1031, UPS, Toulouse, France

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Bénédicte Gaborit Aix Marseille University, INSERM, INRA, C2VN, Marseille, France

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Inès Abdesselam Aix Marseille University, INSERM, INRA, C2VN, Marseille, France

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Marie Maraninchi Aix Marseille University, INSERM, INRA, C2VN, Marseille, France

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Marion Nowicki Aix Marseille University, INSERM, INRA, C2VN, Marseille, France

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René Valéro Aix Marseille University, INSERM, INRA, C2VN, Marseille, France
Nutrition, Metabolic Diseases and Endocrinology Department, AP-HM, La Conception Hospital, Marseille, France

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Maxime Guye AP-HM, Timone, CEMEREM, Marseille, France

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Monique Bernard AP-HM, Timone, CEMEREM, Marseille, France
Aix-Marseille University, CNRS, CRMBM, Marseille, France

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Pascal Auquier Research Unit EA 3279 and Department of Public Health, Aix-Marseille University, Marseille, France

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Hervé Chambost Department of Pediatric Hematology and Oncology, AP-HM, Timone Enfants Hospital, Marseille, France

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Marie-Christine Alessi Aix Marseille University, INSERM, INRA, C2VN, Marseille, France

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Sophie Béliard Aix Marseille University, INSERM, INRA, C2VN, Marseille, France
Nutrition, Metabolic Diseases and Endocrinology Department, AP-HM, La Conception Hospital, Marseille, France

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0.12 sSAT (cm 2 , mean ±  s.d. ) 265 ± 94 196 ± 96 0.15 106 ± 42 111 ± 62 0.76 178 ± 107 165 ± 92 0.79 AT, adipose tissue; intra-abdominal AT = dSAT+VAT; dSAT, deep SAT; SAT, subcutaneous adipose tissue; sSAT

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0497
Volume/Issue:
Volume 8: Issue 4
Open access
Jing Li School of Physical Education, Liaoning Normal University, Dalian, Liaoning, China

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Xuejie Yi Exercise and Health Research Center, Department of Kinesiology, Laboratory Management Center, Shenyang Sport University, Shenyang, Liaoning, China

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Tao Li Exercise and Health Research Center, Department of Kinesiology, Laboratory Management Center, Shenyang Sport University, Shenyang, Liaoning, China

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Tingting Yao School of Physical Education, Liaoning Normal University, Dalian, Liaoning, China

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Dongyang Li Exercise and Health Research Center, Department of Kinesiology, Laboratory Management Center, Shenyang Sport University, Shenyang, Liaoning, China

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Guangxuan Hu Exercise and Health Research Center, Department of Kinesiology, Laboratory Management Center, Shenyang Sport University, Shenyang, Liaoning, China

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Yongqi Ma Exercise and Health Research Center, Department of Kinesiology, Laboratory Management Center, Shenyang Sport University, Shenyang, Liaoning, China

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Bo Chang Exercise and Health Research Center, Department of Kinesiology, Laboratory Management Center, Shenyang Sport University, Shenyang, Liaoning, China

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Shicheng Cao Department of Sports Medicine, School of Public and Basic Sciences, China Medical University, Shenyang, Liaoning, China

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IRISIN is not only a muscle factor but also an adipose factor ( 17 ). As an adipose factor, the expression of FNDC5 is downregulated in the visceral and s.c. adipose tissue of patients with obesity ( 18 , 19 ), making the mechanism of IRISIN regulation

Article Type:
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Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-21-0625
Volume/Issue:
Volume 11: Issue 3
Open access