A Rouland
A Rouland
Endocrinology Diabetics and Metabolic Disorders Department, Dijon University Hospital, Dijon, France
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J-C Chauvet-Gelinier
J-C Chauvet-Gelinier
Psychiatry Unit, Department of Neurosciences, Dijon University Hospital, Dijon, France
INSERM Unit, LNC-UMR 1231, University of Burgundy, Dijon, France
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INSERM Unit, LNC-UMR 1231, University of Burgundy, Dijon, France
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A-L Sberna
A-L Sberna
Endocrinology Diabetics and Metabolic Disorders Department, Dijon University Hospital, Dijon, France
INSERM Unit, LNC-UMR 1231, University of Burgundy, Dijon, France
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INSERM Unit, LNC-UMR 1231, University of Burgundy, Dijon, France
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E Crevisy
E Crevisy
Endocrinology Diabetics and Metabolic Disorders Department, Dijon University Hospital, Dijon, France
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P Buffier
P Buffier
Endocrinology Diabetics and Metabolic Disorders Department, Dijon University Hospital, Dijon, France
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T Mouillot
T Mouillot
Endocrinology Diabetics and Metabolic Disorders Department, Dijon University Hospital, Dijon, France
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J-M Petit
J-M Petit
Endocrinology Diabetics and Metabolic Disorders Department, Dijon University Hospital, Dijon, France
INSERM Unit, LNC-UMR 1231, University of Burgundy, Dijon, France
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INSERM Unit, LNC-UMR 1231, University of Burgundy, Dijon, France
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B Vergès
B Vergès
Endocrinology Diabetics and Metabolic Disorders Department, Dijon University Hospital, Dijon, France
INSERM Unit, LNC-UMR 1231, University of Burgundy, Dijon, France
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INSERM Unit, LNC-UMR 1231, University of Burgundy, Dijon, France
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Introduction Type 1 (T1D) and type 2 diabetes (T2D) are chronic diseases in which psychological determinants are an important field of research, not only to improve personalized treatment and educational strategies, but also to directly
Ali Abbasi
Ali Abbasi
MRC Epidemiology Unit, Department of Epidemiology and Department of Internal Medicine, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Addenbrooke's Hospital, Post Box 285, Cambridge CB2 0QQ, UK
MRC Epidemiology Unit, Department of Epidemiology and Department of Internal Medicine, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Addenbrooke's Hospital, Post Box 285, Cambridge CB2 0QQ, UK
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MRC Epidemiology Unit, Department of Epidemiology and Department of Internal Medicine, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Addenbrooke's Hospital, Post Box 285, Cambridge CB2 0QQ, UK
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Introduction Over the past decade, interest in studying biological markers (biomarkers) for type 2 diabetes (T2D) has increased intensely. This happened because multiple pathobiological processes may contribute to the disease progression, which
Ram P Narayanan
Ram P Narayanan
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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Bo Fu
Bo Fu
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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Adrian H Heald
Adrian H Heald
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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Kirk W Siddals
Kirk W Siddals
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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Robert L Oliver
Robert L Oliver
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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Julie E Hudson
Julie E Hudson
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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Antony Payton
Antony Payton
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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Simon G Anderson
Simon G Anderson
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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Anne White
Anne White
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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William E R Ollier
William E R Ollier
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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J Martin Gibson
J Martin Gibson
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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Vascular Research Group, School of Community Based Medicine, Centre for Integrated Genomic Medical Research, Cardiovascular Research Group, Endocrinology and Diabetes, Salford R&D, Department of Endocrinology and Diabetes, Faculty of Medical, Human and Life Sciences, The University of Manchester, Manchester M13 9PT, UK
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the renal glomerulus (3) . In this study, we used ‘real-world’ data to examine the hypothesis that concentrations of IGF2 and IGFBP2 at baseline were associated with longitudinal trends in glomerular filtration rate (GFR) in type 2 diabetes. Subjects
Qiu-ming Yao
Qiu-ming Yao
Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China
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Bin Wang
Bin Wang
Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China
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Xiao-fei An
Xiao-fei An
Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China
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Jin-an Zhang
Jin-an Zhang
Department of Endocrinology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China
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Liumei Ding
Liumei Ding
Department of Clinical Laboratory, Jinshan Hospital of Fudan University, Shanghai, China
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Introduction Diabetes is a public health issue, and there are over 0.4 billion people suffering from diabetes over the world, and its prevalence is still increasing remarkably every year ( 1 ). Type 2 diabetes mellitus (T2DM) is the major type
Xi Zhang
Xi Zhang
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Xiurong Shen
Xiurong Shen
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Graduate School, Wannan Medical College, Wuhu, Anhui, People’s Republic of China
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Wan Zhou
Wan Zhou
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Mengyun Xu
Mengyun Xu
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Yan Xing
Yan Xing
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Jianping Weng
Jianping Weng
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Shandong Ye
Shandong Ye
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Suowen Xu
Suowen Xu
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Zhi Zhang
Zhi Zhang
Hefei National Laboratory for Physical Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Wei Wang
Wei Wang
Department of Endocrinology and Laboratory for Diabetes, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Institute of Endocrine and Metabolic Diseases, University of Science and Technology of China, Hefei, Anhui, People’s Republic of China
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Introduction Type 2 diabetes (T2D), the most common form of diabetes, has fallen into the leading causes of disability and death worldwide. The harms of T2D arise from its complications such as neuropathy, nephropathy, retinopathy, and
Richard H Tuligenga
Richard H Tuligenga
INSERM U1018, Université Paris Sud, Centre for Research in Epidemiology and Population Health, Hôpital Paul Brousse, Bât 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Paris, Villejuif Cedex, France
INSERM U1018, Université Paris Sud, Centre for Research in Epidemiology and Population Health, Hôpital Paul Brousse, Bât 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Paris, Villejuif Cedex, France
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INSERM U1018, Université Paris Sud, Centre for Research in Epidemiology and Population Health, Hôpital Paul Brousse, Bât 15/16, 16 Avenue Paul Vaillant Couturier, 94807 Paris, Villejuif Cedex, France
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Introduction Patients with type 2 diabetes mellitus show faster cognitive decline compared with healthy subjects (1) . Numerous studies in patients with type 2 diabetes have dealt with the association between the level of glycaemic control and the
Emanuela Zaharieva
Emanuela Zaharieva
Department of Internal Medicine, University Hospital Alexandrovska, Clinic of Endocrinology, Faculty of Medicine, Medical University-Sofia, Sofia, Bulgaria
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Zdravko Kamenov
Zdravko Kamenov
Department of Internal Medicine, University Hospital Alexandrovska, Clinic of Endocrinology, Faculty of Medicine, Medical University-Sofia, Sofia, Bulgaria
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Tsvetelina Velikova
Tsvetelina Velikova
Department of Clinical Immunology, University Hospital St. Ivan Rilski, Laboratory of Clinical Immunology, Faculty of Medicine, Medical University-Sofia, Sofia, Bulgaria
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Adelina Tsakova
Adelina Tsakova
Department of Clinical Laboratory, University Hospital Alexandrovska, Central Clinical Laboratory, Faculty of Medicine, Medical University-Sofia, Sofia, Bulgaria
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Yosif El-Darawish
Yosif El-Darawish
Laboratory of Tumor Immunology and Cell Therapy, Hyogo College of Medicine, Hyogo, Japan
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Haruki Okamura
Haruki Okamura
Laboratory of Tumor Immunology and Cell Therapy, Hyogo College of Medicine, Hyogo, Japan
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helper immune response ( 3 , 4 ). Apart from its place in immune defense against infective pathogens, IL-18 participates in the pathogenesis of atopic, autoimmune and chronic inflammatory diseases ( 3 , 4 ). Obesity and type 2 diabetes (T2D) have been
Merlin C Thomas
Merlin C Thomas
Department of Diabetes, Central Clinical School, Monash University, Melbourne, VIC, Australia
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Brendon L Neuen
Brendon L Neuen
The George Institute for Global Health, Sydney, NSW, Australia
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Stephen M Twigg
Stephen M Twigg
The University of Sydney School of Medicine, Sydney, NSW, Australia
Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
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Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, NSW, Australia
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Mark E Cooper
Mark E Cooper
Department of Diabetes, Central Clinical School, Monash University, Melbourne, VIC, Australia
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Sunil V Badve
Sunil V Badve
The George Institute for Global Health, Sydney, NSW, Australia
Department of Renal Medicine, St George Hospital, Sydney, NSW, Australia
Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia
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Department of Renal Medicine, St George Hospital, Sydney, NSW, Australia
Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia
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Introduction At least half of all adults with type 2 diabetes (T2D) have comorbid chronic kidney disease (CKD), with either an elevated urinary albumin excretion rate (uAER) and/or a reduced estimated glomerular filtration rate (eGFR) ( 1 , 2
Alessandra Gambineri
Alessandra Gambineri
Endocrinology Unit, Department of Medical and Surgical Sciences, St Orsola-Malpighi Hospital, Alma Mater University of Bologna, Bologna, Italy
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Carla Pelusi
Carla Pelusi
Endocrinology Unit, Department of Medical and Surgical Sciences, St Orsola-Malpighi Hospital, Alma Mater University of Bologna, Bologna, Italy
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Role of sex and gender on the development of type 2 diabetes There is increasing evidence that sex and gender differences influence the epidemiology, pathophysiology, treatment and outcomes of many diseases, including type 2 diabetes (T2DM
Cheryl M Isherwood
Cheryl M Isherwood
Section of Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom
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M Denise Robertson
M Denise Robertson
Section of Metabolic Medicine, Food and Macronutrients, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom
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Debra J Skene
Debra J Skene
Section of Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom
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Jonathan D Johnston
Jonathan D Johnston
Section of Chronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom
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obesity, type 2 diabetes mellitus (T2D) and circadian rhythmicity have been reviewed elsewhere ( 12 ). In one notable study, mice made obese by a high-fat diet exhibit reduced amplitude of circadian rhythms ( 17 ), although these effects may be due to diet
