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Morten Winkler Møller, Marianne Skovsager Andersen, Christian Bonde Pedersen, Bjarne Winther Kristensen, and Frantz Rom Poulsen

). For other PAs, except prolactinomas, surgery is the first choice of treatment. The primary surgical technique has been transsphenoidal surgery since Hardy introduced surgical microscopes in 1962 ( 9 ). Further development of this technique has improved

Open access

Ida Staby, Jesper Krogh, Marianne Klose, Jonas Baekdal, Ulla Feldt-Rasmussen, Lars Poulsgaard, Jacob Bertram Springborg, and Mikkel Andreassen

to investigate the overall effect of transsphenoidal surgery on the pituitary endocrine function by comparing the numbers of insufficient axis before and after transsphenoidal surgery in a cohort of consecutive patients treated within the last 2 years

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Alberto Giacinto Ambrogio, Massimiliano Andrioli, Martina De Martin, Francesco Cavagnini, and Francesca Pecori Giraldi

assess the pattern of ACTH/cortisol responses to desmopressin in the years following transsphenoidal surgery in patients with Cushing’s disease on long-term remission and to establish whether changes in the response to desmopressin in patients during

Open access

Nidan Qiao

Introduction Cushing’s disease (CD) is a subtype of pituitary adenoma with hypercortisolism and presents a particular challenge to neurosurgeons. Transsphenoidal surgery (TS) has long been the standard of care for patients with CD ( 1 , 2

Open access

Boni Xiang, Ran Tao, Xinhua Liu, Xiaoming Zhu, Min He, Zengyi Ma, Yehong Yang, Zhaoyun Zhang, Yiming Li, Zhenwei Yao, Yongfei Wang, and Hongying Ye

. Marked correlations between thyroid hormones and serum cortisol were observed. All patients received transsphenoidal surgery at the same clinic by an experienced surgeon. Therefore, we considered that the changes of thyroid hormones in CD were related to

Open access

Emmanuelle Motte, Anya Rothenbuhler, Stephan Gaillard, Najiba Lahlou, Cécile Teinturier, Régis Coutant, and Agnès Linglart

suspected ( 9 ), the treatment remains a challenge. The gold standard treatment for both pediatric and adult patients with CD is transsphenoidal surgery (TSS) with selective microadenomectomy, but the failure rate is about 25–50% ( 10 , 11 , 12 , 13 , 14

Open access

Prachi Bansal, Anurag Lila, Manjunath Goroshi, Swati Jadhav, Nilesh Lomte, Kunal Thakkar, Atul Goel, Abhidha Shah, Shilpa Sankhe, Naina Goel, Neelam Jaguste, Tushar Bandgar, and Nalini Shah

mortality ( 2 ). Transsphenoidal surgery (TSS) of pituitary adenoma is the primary treatment modality, with varying remission rates (52–96.6%) reported across different centres ( 3 ). Various demographic, biochemical, radiological and histopathological

Open access

Liza Das, Kim Vaiphei, Ashutosh Rai, Chirag Kamal Ahuja, Paramjeet Singh, Ishani Mohapatra, Rajesh Chhabra, Anil Bhansali, Bishan Dass Radotra, Ashley B Grossman, Márta Korbonits, and Pinaki Dutta

choice for symptomatic PPT usually by the transsphenoidal route (TSS). However, PPTs, including both pituicytomas and SCOs, often show recurrence/persistence following surgery ( 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28

Open access

Kunal Thakkar, Swati Ramteke-Jadhav, Rajeev Kasaliwal, Saba Samad Memon, Virendra Patil, Puja Thadani, Nilesh Lomte, Shilpa Sankhe, Atul Goel, Sridhar Epari, Naina Goel, Anurag Lila, Nalini S Shah, and Tushar Bandgar

craniophayngiomas (especially in children) ( 20 ) or might mimic pituitary macroadenoma in adults ( 22 ). With uncertain pre-operative diagnosis, our patient underwent TSS and diagnosis was made on histopathology. Trans-sphenoidal surgery seems to be a reasonable

Open access

Kush Dev Singh Jarial, Anil Bhansali, Vivek Gupta, Paramjeet Singh, Kanchan K Mukherjee, Akhilesh Sharma, Rakesh K Vashishtha, Suja P Sukumar, Naresh Sachdeva, and Rama Walia

signs, ACTH-dependent hypercortisolemia, non-suppressible cortisol dynamics, sellar imaging either normal or showing pituitary microadenoma and adenoma or carcinoid on histopathology following trans-sphenoidal or appropriate surgery. Twenty