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Anastasia P Athanasoulia-Kaspar, Matthias K Auer, Günter K Stalla and Mira Jakovcevski

Introduction Telomeres are noncoding DNA regions located at the end of chromosomes consisting of repetitive DNA sequences. Their primary purpose is to protect the chromosome from degradation processes and from loss of genetic material during

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Andrew R Dismukes, Vanessa J Meyer, Elizabeth A Shirtcliff, Katherine P Theall, Kyle C Esteves and Stacy S Drury

influence physiology through its conversion to other sex steroids and metabolites indicating the potential for a diverse pattern of downstream effects. Similar to DHEA, telomere length (TL) has also been associated with a range of factors linked to

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E N Dudinskaya, O N Tkacheva, M V Shestakova, N V Brailova, I D Strazhesko, D U Akasheva, O Y Isaykina, N V Sharashkina, D A Kashtanova and S A Boytsov

the most widely discussed genetic ageing markers is the peripheral blood lymphocyte telomere length. Lymphocyte telomeres are the ends of linear DNA that have the repetitive nucleotide sequence TTAGGG. Telomeres protect linear chromosome ends from

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Dario de Biase, Federica Torricelli, Moira Ragazzi, Benedetta Donati, Elisabetta Kuhn, Michela Visani, Giorgia Acquaviva, Annalisa Pession, Giovanni Tallini, Simonetta Piana and Alessia Ciarrocchi

). Unlimited replicative potential is a major hallmark of aggressive cancer cells ( 25 ). To fulfill the high rate of proliferation, cancer cells must protect their telomere repeats length from progressive shortening ( 26 , 27 ). The telomerase complex of

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Ali Abbasi

+ TT – Europe, Asia, Africa/2013 4011/4303 rs12134663, rs1801133/ MTHFR OR, 1.29 5 μmol/l IL-1Ra 1 (26) DIAGRAMv3 and EPIC-InterAct US, Europe/2015 18 715/61 692 rs6743376, rs1542176/ IL1RN Null Leukocyte telomere length 1 (46) WHI-OS US/2012 1675

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Weixi Wang, Rulai Han, Lei Ye, Jing Xie, Bei Tao, Fukang Sun, Ran Zhuo, Xi Chen, Xiaxing Deng, Cong Ye, Hongyan Zhao and Shu Wang

 bp from MEN1 transcription start site) and D11S1983, transcribing from telomere to centromere. D11S4940 is located approximately 93 kb 5′ of MEN1 gene. The STR markers were amplified by fluorescent carboxyfluorescein (FAM)-labeled primers. The PCR

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Mardia López-Alarcón, Jessie N Zurita-Cruz, Alonso Torres-Rodríguez, Karla Bedia-Mejía, Manuel Pérez-Güemez, Leonel Jaramillo-Villanueva, Mario E Rendón-Macías, Jose R Fernández and Patricia Martínez-Maroñas

66 – 74 . ( https://doi.org/10.1016/j.ctim.2017.04.003 ) 13 Buss J Havel PJ Epel E Lin J Blackburn E Daubenmier J . Associations of ghrelin with eating behaviors, stress, metabolic factors, and telomere length among overweight and obese

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Ana P Estrada-Flórez, Mabel E Bohórquez, Alejandro Vélez, Carlos S Duque, Jorge H Donado, Gilbert Mateus, Cesar Panqueba-Tarazona, Guadalupe Polanco-Echeverry, Ruta Sahasrabudhe, Magdalena Echeverry and Luis G Carvajal-Carmona

telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas . Oncogene 2014 4978 – 4984 . ( https://doi.org/10.1038/onc.2013.446 ) 22 Liu X Qu S Liu R Sheng C Shi X Zhu G Murugan AK Guan H Yu H Wang Y

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Rossella Cannarella, Teresa Mattina, Rosita A Condorelli, Laura M Mongioì, Giuseppe Pandini, Sandro La Vignera and Aldo E Calogero

15q (q21.3→26.3) associated with the deletion of the 15q telomere and part of the 15q26.3 band. She had a severe clinical course due to congenital heart defect, horseshoe kidney, hand contractures and clubfeet and death occurred after 20 days from

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Kjell Oberg, Eric Krenning, Anders Sundin, Lisa Bodei, Mark Kidd, Margot Tesselaar, Valentina Ambrosini, Richard P Baum, Matthew Kulke, Marianne Pavel, Jaroslaw Cwikla, Ignat Drozdov, Massimo Falconi, Nicola Fazio, Andrea Frilling, Robert Jensen, Klaus Koopmans, Tiny Korse, Dik Kwekkeboom, Helmut Maecke, Giovanni Paganelli, Ramon Salazar, Stefano Severi, Jonathan Strosberg, Vikas Prasad, Aldo Scarpa, Ashley Grossman, Annemeik Walenkamp, Mauro Cives, Irene Virgolini, Andreas Kjaer and Irvin M Modlin

. Gastrointestinal Endoscopy 2015 81 159 – 167.e152 . ( doi:10.1016/j.gie.2014.09.037 ) 80 Shay JW Reddel RR Wright WE. Cancer and telomeres – an alternative to telomerase . Science 2012 336 1388 – 1390 . ( doi:10.1126/science.1222394