Filter

Refine by collections

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 1 - 10 of 20 items for :

Clear All
Andrew R Dismukes Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA
Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

Search for other papers by Andrew R Dismukes in
Google Scholar
PubMed Close
,
Vanessa J Meyer Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA
Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

Search for other papers by Vanessa J Meyer in
Google Scholar
PubMed Close
,
Elizabeth A Shirtcliff Department of Human Development and Family Studies, Iowa State University, Ames, Iowa, USA

Search for other papers by Elizabeth A Shirtcliff in
Google Scholar
PubMed Close
,
Katherine P Theall Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

Search for other papers by Katherine P Theall in
Google Scholar
PubMed Close
,
Kyle C Esteves Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

Search for other papers by Kyle C Esteves in
Google Scholar
PubMed Close
, and
Stacy S Drury Tulane University School of Medicine, Department of Psychiatry, Division of Child and Adolescent Psychiatry, Tulane University, New Orleans, Louisiana, USA

Search for other papers by Stacy S Drury in
Google Scholar
PubMed Close

stress on TL, and other subsequent biological systems known to deteriorate with aging. Pathway 2: the antiglucocorticoid hypothesis In vitro cortisol exposure is associated with decreased telomerase ( 23 ), the enzyme responsible for repairing

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-16-0007
Volume/Issue:
Volume 5: Issue 3
Open access
Anastasia P Athanasoulia-Kaspar Clinical Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany

Search for other papers by Anastasia P Athanasoulia-Kaspar in
Google Scholar
PubMed Close
,
Matthias K Auer Clinical Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Ludwig-Maximilians-Universität München, Munich, Germany

Search for other papers by Matthias K Auer in
Google Scholar
PubMed Close
,
Günter K Stalla Clinical Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany

Search for other papers by Günter K Stalla in
Google Scholar
PubMed Close
, and
Mira Jakovcevski Department of Stress Neurobiology and Neurogenetics, Max Planck Institute of Psychiatry, Munich, Germany

Search for other papers by Mira Jakovcevski in
Google Scholar
PubMed Close

cell division. When telomeres reach a critical short length, cell division is terminated and the corresponding cells undergo apoptosis ( 1 ). Telomerase, the key enzyme relevant for telomeric DNA synthesis and maintenance of telomere length (TL) is

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0362
Volume/Issue:
Volume 7: Issue 11
Open access
Dario de Biase Department of Pharmacy and Biotechnology (Dipartimento di Farmacia e Biotecnologie) – Molecular Diagnostic Unit, Azienda USL di Bologna, University of Bologna, Bologna, Italy

Search for other papers by Dario de Biase in
Google Scholar
PubMed Close
,
Federica Torricelli Laboratory of Translational Research, Azienda Unità Sanitaria Locale AUSL-IRCCS, Reggio Emilia, Italy

Search for other papers by Federica Torricelli in
Google Scholar
PubMed Close
,
Moira Ragazzi Pathology Unit, Azienda Unità Sanitaria Locale AUSL-IRCCS, Reggio Emilia, Italy

Search for other papers by Moira Ragazzi in
Google Scholar
PubMed Close
,
Benedetta Donati Laboratory of Translational Research, Azienda Unità Sanitaria Locale AUSL-IRCCS, Reggio Emilia, Italy

Search for other papers by Benedetta Donati in
Google Scholar
PubMed Close
,
Elisabetta Kuhn Pathology Unit, Azienda Unità Sanitaria Locale AUSL-IRCCS, Reggio Emilia, Italy

Search for other papers by Elisabetta Kuhn in
Google Scholar
PubMed Close
,
Michela Visani Department of Medicine (Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale) – Molecular Diagnostic Unit, Azienda USL di Bologna, University of Bologna School of Medicine, Bologna, Italy

Search for other papers by Michela Visani in
Google Scholar
PubMed Close
,
Giorgia Acquaviva Department of Medicine (Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale) – Molecular Diagnostic Unit, Azienda USL di Bologna, University of Bologna School of Medicine, Bologna, Italy

Search for other papers by Giorgia Acquaviva in
Google Scholar
PubMed Close
,
Annalisa Pession Department of Pharmacy and Biotechnology (Dipartimento di Farmacia e Biotecnologie) – Molecular Diagnostic Unit, Azienda USL di Bologna, University of Bologna, Bologna, Italy

Search for other papers by Annalisa Pession in
Google Scholar
PubMed Close
,
Giovanni Tallini Department of Medicine (Dipartimento di Medicina Specialistica, Diagnostica e Sperimentale) – Molecular Diagnostic Unit, Azienda USL di Bologna, University of Bologna School of Medicine, Bologna, Italy

Search for other papers by Giovanni Tallini in
Google Scholar
PubMed Close
,
Simonetta Piana Pathology Unit, Azienda Unità Sanitaria Locale AUSL-IRCCS, Reggio Emilia, Italy

Search for other papers by Simonetta Piana in
Google Scholar
PubMed Close
, and
Alessia Ciarrocchi Laboratory of Translational Research, Azienda Unità Sanitaria Locale AUSL-IRCCS, Reggio Emilia, Italy

Search for other papers by Alessia Ciarrocchi in
Google Scholar
PubMed Close

). Unlimited replicative potential is a major hallmark of aggressive cancer cells ( 25 ). To fulfill the high rate of proliferation, cancer cells must protect their telomere repeats length from progressive shortening ( 26 , 27 ). The telomerase complex of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0386
Volume/Issue:
Volume 7: Issue 12
Open access
Abdul K Siraj Human Cancer Genomic Research, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Abdul K Siraj in
Google Scholar
PubMed Close
,
Rong Bu Human Cancer Genomic Research, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Rong Bu in
Google Scholar
PubMed Close
,
Maham Arshad Human Cancer Genomic Research, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Maham Arshad in
Google Scholar
PubMed Close
,
Kaleem Iqbal Human Cancer Genomic Research, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Kaleem Iqbal in
Google Scholar
PubMed Close
,
Sandeep Kumar Parvathareddy Human Cancer Genomic Research, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Sandeep Kumar Parvathareddy in
Google Scholar
PubMed Close
,
Tariq Masoodi Human Cancer Genomic Research, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Tariq Masoodi in
Google Scholar
PubMed Close
,
Laila Omar Ghazwani Human Cancer Genomic Research, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Laila Omar Ghazwani in
Google Scholar
PubMed Close
,
Saif S Al-Sobhi Department of Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Saif S Al-Sobhi in
Google Scholar
PubMed Close
,
Fouad Al-Dayel Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Fouad Al-Dayel in
Google Scholar
PubMed Close
, and
Khawla S Al-Kuraya Human Cancer Genomic Research, Research Centre, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Khawla S Al-Kuraya in
Google Scholar
PubMed Close

2011 2011 915925 . ( https://doi.org/10.5402/2011/915925 ) 2 Bu R Siraj AK Divya SP Kong Y Parvathareddy SK Al‐Rasheed M Al‐Obaisi KA Victoria IG Al‐Sobhi SS Al‐Dawish M , Telomerase reverse transcriptase

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0258
Volume/Issue:
Volume 9: Issue 9
Open access
Serena Martinelli Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy

Search for other papers by Serena Martinelli in
Google Scholar
PubMed Close
,
Mario Maggi Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy

Search for other papers by Mario Maggi in
Google Scholar
PubMed Close
, and
Elena Rapizzi Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy

Search for other papers by Elena Rapizzi in
Google Scholar
PubMed Close

have shown that it is possible to immortalise cells, with minimal alteration of the phenotype, by introducing human telomerase reverse transcriptase (hTERT) into human cells ( 40 , 41 ). In 2013, Ghayee et al . applied this technology in an attempt to

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0472
Volume/Issue:
Volume 9: Issue 12
Open access
Dongyan Han Department of Pathology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China

Search for other papers by Dongyan Han in
Google Scholar
PubMed Close
,
Min Ding Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Search for other papers by Min Ding in
Google Scholar
PubMed Close
,
Rongli Xie Department of General Surgery, RuiJin Hospital Lu Wan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China

Search for other papers by Rongli Xie in
Google Scholar
PubMed Close
,
Zhengshi Wang Thyroid Center, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China
Shanghai Center of Thyroid Diseases, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China

Search for other papers by Zhengshi Wang in
Google Scholar
PubMed Close
,
Guohui Xiao Department of General Surgery, Pancreatic Disease Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Search for other papers by Guohui Xiao in
Google Scholar
PubMed Close
,
Xiaohong Wang Shanghai Rigen Biotechnology Co., Ltd. Shanghai, China

Search for other papers by Xiaohong Wang in
Google Scholar
PubMed Close
,
Lei Dong Department of Pathology, Shanghai Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Search for other papers by Lei Dong in
Google Scholar
PubMed Close
,
Zhiqiang Yin Thyroid Center, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China
Shanghai Center of Thyroid Diseases, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China

Search for other papers by Zhiqiang Yin in
Google Scholar
PubMed Close
, and
Jian Fei Department of General Surgery, Pancreatic Disease Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Research Institute of Pancreatic Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China
State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Shanghai Jiao Tong University, Shanghai, China
Institute of Translational Medicine, Shanghai Jiao Tong University, Shanghai, China

Search for other papers by Jian Fei in
Google Scholar
PubMed Close

human cancers ( 15 , 16 ). TERT encodes the telomerase protein, and telomerase overexpression confers the ability to split infinitely into cancer cells ( 17 ), including thyroid cancer cells ( 18 ). Medullary thyroid carcinoma (MTC) accounts for

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-23-0135
Volume/Issue:
Volume 12: Issue 8
Open access
Daniel Alexander Hescheler Department of Nuclear Medicine, University Hospital Münster, Münster, Germany
European Institute for Molecular Imaging (EIMI), University of Münster, Münster, Germany

Search for other papers by Daniel Alexander Hescheler in
Google Scholar
PubMed Close
,
Milan Janis Michael Hartmann Department of General, Visceral, Tumor and Transplant Surgery, University Hospital Cologne, Cologne, Germany

Search for other papers by Milan Janis Michael Hartmann in
Google Scholar
PubMed Close
,
Burkhard Riemann Department of Nuclear Medicine, University Hospital Münster, Münster, Germany

Search for other papers by Burkhard Riemann in
Google Scholar
PubMed Close
,
Maximilian Michel Institute of Zoology, University of Cologne Germany, Cologne, Germany

Search for other papers by Maximilian Michel in
Google Scholar
PubMed Close
,
Christiane Josephine Bruns Department of General, Visceral, Tumor and Transplant Surgery, University Hospital Cologne, Cologne, Germany

Search for other papers by Christiane Josephine Bruns in
Google Scholar
PubMed Close
,
Hakan Alakus Department of General, Visceral, Tumor and Transplant Surgery, University Hospital Cologne, Cologne, Germany

Search for other papers by Hakan Alakus in
Google Scholar
PubMed Close
, and
Costanza Chiapponi Department of General, Visceral, Tumor and Transplant Surgery, University Hospital Cologne, Cologne, Germany

Search for other papers by Costanza Chiapponi in
Google Scholar
PubMed Close

encoding for telomerase reverse transcriptase; tp53 , gene encoding for tumor protein p53; TS, target sequencing; WES, whole exome sequencing; WGS, whole genome sequencing. FDA-approved targeted therapy and their biological targets In order

Article Type:
Research Article
Collections:
Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-21-0624
Volume/Issue:
Volume 11: Issue 4
Open access
Luis Eduardo Barbalho de Mello Genetic Bases of Thyroid Tumors Laboratory, Division of Genetics, Department of Morphology and Genetics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil
Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil

Search for other papers by Luis Eduardo Barbalho de Mello in
Google Scholar
PubMed Close
,
Thaise Nayane Ribeiro Carneiro Genetic Bases of Thyroid Tumors Laboratory, Division of Genetics, Department of Morphology and Genetics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

Search for other papers by Thaise Nayane Ribeiro Carneiro in
Google Scholar
PubMed Close
,
Aline Neves Araujo Genetic Bases of Thyroid Tumors Laboratory, Division of Genetics, Department of Morphology and Genetics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

Search for other papers by Aline Neves Araujo in
Google Scholar
PubMed Close
,
Camila Xavier Alves Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil

Search for other papers by Camila Xavier Alves in
Google Scholar
PubMed Close
,
Pedro Alexandre Favoretto Galante Centro de Oncologia Molecular, Hospital Sírio-libanês, São Paulo, São Paulo, Brazil

Search for other papers by Pedro Alexandre Favoretto Galante in
Google Scholar
PubMed Close
,
Vanessa Candiotti Buzatto Centro de Oncologia Molecular, Hospital Sírio-libanês, São Paulo, São Paulo, Brazil

Search for other papers by Vanessa Candiotti Buzatto in
Google Scholar
PubMed Close
,
Maria das Graças de Almeida Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil
Department of Clinical and Toxicological Analyses, Natal, Rio Grande do Norte, Brazil

Search for other papers by Maria das Graças de Almeida in
Google Scholar
PubMed Close
,
Karina Marques Vermeulen-Serpa Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil

Search for other papers by Karina Marques Vermeulen-Serpa in
Google Scholar
PubMed Close
,
Sancha Helena de Lima Vale Department of Clinical and Toxicological Analyses, Natal, Rio Grande do Norte, Brazil
Department of Nutrition, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil

Search for other papers by Sancha Helena de Lima Vale in
Google Scholar
PubMed Close
,
Fernando José de Pinto Paiva Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil

Search for other papers by Fernando José de Pinto Paiva in
Google Scholar
PubMed Close
,
José Brandão-Neto Postgraduate Program in Health Sciences, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil

Search for other papers by José Brandão-Neto in
Google Scholar
PubMed Close
, and
Janete Maria Cerutti Genetic Bases of Thyroid Tumors Laboratory, Division of Genetics, Department of Morphology and Genetics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil

Search for other papers by Janete Maria Cerutti in
Google Scholar
PubMed Close

://doi.org/10.1056/NEJMoa1502449 ) 28 Capezzone M Cantara S Marchisotta S Filetti S De Santi MM Rossi B Ronga G Durante C Pacini F . Short telomeres, telomerase reverse transcriptase gene amplification, and increased telomerase activity in

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-21-0406
Volume/Issue:
Volume 11: Issue 1
Open access
E N Dudinskaya
Search for other papers by E N Dudinskaya in
Google Scholar
PubMed Close
,
O N Tkacheva
Search for other papers by O N Tkacheva in
Google Scholar
PubMed Close
,
M V Shestakova National Research Center for Preventive Medicine, Endocrinology Research Centre, Building 10, Petroverigskiy Lane, Moscow 101990, Russian Federation

Search for other papers by M V Shestakova in
Google Scholar
PubMed Close
,
N V Brailova
Search for other papers by N V Brailova in
Google Scholar
PubMed Close
,
I D Strazhesko
Search for other papers by I D Strazhesko in
Google Scholar
PubMed Close
,
D U Akasheva
Search for other papers by D U Akasheva in
Google Scholar
PubMed Close
,
O Y Isaykina
Search for other papers by O Y Isaykina in
Google Scholar
PubMed Close
,
N V Sharashkina
Search for other papers by N V Sharashkina in
Google Scholar
PubMed Close
,
D A Kashtanova
Search for other papers by D A Kashtanova in
Google Scholar
PubMed Close
, and
S A Boytsov
Search for other papers by S A Boytsov in
Google Scholar
PubMed Close

– 185 . ( doi:10.1161/01.HYP.0000113081.42868.f4 ). 10 Blackburn EH Greider CW Szostak JW . Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging . Nature Medicine 2006 12 1133 – 1138 . ( doi:10

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-15-0041
Volume/Issue:
Volume 4: Issue 3
Open access
Zhen-yu Song Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China

Search for other papers by Zhen-yu Song in
Google Scholar
PubMed Close
,
Qiuming Yao Department of Endocrinology, Jinshan Hospital of Fudan University, Shanghai, China

Search for other papers by Qiuming Yao in
Google Scholar
PubMed Close
,
Zhiyuan Zhuo Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China

Search for other papers by Zhiyuan Zhuo in
Google Scholar
PubMed Close
,
Zhe Ma Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China

Search for other papers by Zhe Ma in
Google Scholar
PubMed Close
, and
Gang Chen Department of Urology, Jinshan Hospital of Fudan University, Shanghai, China

Search for other papers by Gang Chen in
Google Scholar
PubMed Close

. ( https://doi.org/10.1210/endo.141.1.7289 ) 39 Ikeda N Uemura H Ishiguro H Hori M Hosaka M Kyo S Miyamoto K Takeda E Kubota Y. Combination treatment with 1alpha,25-dihydroxyvitamin D3 and 9-cis-retinoic acid directly inhibits human telomerase reverse

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0283
Volume/Issue:
Volume 7: Issue 12
Open access