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David C Llewellyn Department of Endocrinology ASO/EASO COM, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, UK

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Rajaventhan Srirajaskanthan Neuroendocrine Tumour Unit, Kings Health Partners ENETS Centre of Excellence, Denmark Hill, London, UK
Faculty of Life Sciences and Medicine, Kings College London, London, UK

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Royce P Vincent Faculty of Life Sciences and Medicine, Kings College London, London, UK
Department of Clinical Biochemistry, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, UK

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Catherine Guy Department of Cellular Pathology, Royal Sussex County Hospital, Eastern Road, Brighton, UK

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Eftychia E Drakou Department of Clinical Oncology, Guy’s Cancer Centre – Guy’s and St Thomas’ NHS Foundation Trust, Great Maze Pond, London, UK

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Simon J B Aylwin Department of Endocrinology ASO/EASO COM, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, UK
Neuroendocrine Tumour Unit, Kings Health Partners ENETS Centre of Excellence, Denmark Hill, London, UK

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Ashley B Grossman Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK
Barts and the London School of Medicine, Centre for Endocrinology, William Harvey Institute, London, UK
Neuroendocrine Tumour Unit, Royal Free Hospital, London, UK

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John K Ramage Neuroendocrine Tumour Unit, Kings Health Partners ENETS Centre of Excellence, Denmark Hill, London, UK
Faculty of Life Sciences and Medicine, Kings College London, London, UK

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Georgios K Dimitriadis Department of Endocrinology ASO/EASO COM, King’s College Hospital NHS Foundation Trust, Denmark Hill, London, UK
Faculty of Life Sciences and Medicine, School of Life Course Sciences, Obesity Immunometabolism and Diabetes Group, King’s College London, London, UK

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hypercalcitonaemia, and review the relevant literature. Methodology This protocol was developed according to the Preferred Reporting Items for Systematic review and Meta-Analysis Protocols (PRISMA-P), and followed methods outlined in The Cochrane Handbook for

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0071
Volume/Issue:
Volume 10: Issue 4
Open access
Maria Luisa Garo Mathsly Research, Roma, Italy

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Désirée Deandreis Division of Nuclear Medicine, Department of Medical Sciences, AOU Città della Salute e della Scienza, University of Turin, Turin, Italy

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Alfredo Campennì Nuclear Medicine Unit, Department of Biomedical and Dental Sciences and Morpho-Functional Imaging, University of Messina, Messina, Italy

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Alexis Vrachimis Department of Nuclear Medicine, German Oncology Center, University Hospital of the European University, Limassol, Cyprus

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Petra Petranovic Ovcaricek Department of Oncology and Nuclear Medicine, University Hospital Center Sestre Milosrdnice, Zagreb, Croatia

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Luca Giovanella Clinic for Nuclear Medicine and Molecular Imaging, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland
Clinic for Nuclear Medicine, University Hospital of Zürich, Zürich, Switzerland

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overdiagnosis could be helpful for the optimal management of PTC patients, but their accuracy is not well-defined yet. Therefore, this systematic review aims to evaluate the accuracy of nomograms developed to predict overall survival (OS), disease-free survival

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-22-0457
Volume/Issue:
Volume 12: Issue 4
Open access
Christian Trummer Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria

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Stefan Pilz Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria

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Verena Schwetz Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria

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Barbara Obermayer-Pietsch Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria

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Elisabeth Lerchbaum Department of Internal Medicine, Division of Endocrinology and Diabetology, Medical University of Graz, Graz, Austria

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metabolism seem to be associated ( 19 , 20 ). Considering the potential link between vitamin D and human fertility, we performed this systematic review summarizing current literature on vitamin D, PCOS and androgen metabolism in men. Methods We

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0009
Volume/Issue:
Volume 7: Issue 3
Open access
Sarah Byberg Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark

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Jesper Futtrup Panum Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Mikkel Andreassen Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark

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Jesper Krogh Department of Medical Endocrinology, Copenhagen University Hospital, Copenhagen, Denmark

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necessarily offered treatment; the same is true for secondary hyperprolactinemia as a side effect to widely used medications, such as antipsychotic drugs or in patients with kidney failure. The purpose of this systematic review was to systematically assess

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0286
Volume/Issue:
Volume 8: Issue 10
Open access
Eng-Loon Tng Department of Medicine, Level 8, Tower A, Ng Teng Fong General Hospital, Singapore

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Yee Sian Tiong Department of Medicine, Level 8, Tower A, Ng Teng Fong General Hospital, Singapore

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Aye Thida Aung Department of Medicine, Level 8, Tower A, Ng Teng Fong General Hospital, Singapore

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Nicole Ya Yuan Chong Department of Medicine, National University Hospital, Singapore

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Zhemin Wang Department of Medicine, National University Hospital, Singapore

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AF (TAF) to ischemic strokes (IS) and systemic thromboembolism (SE). Rationale for this systematic review and meta-analysis Current guidelines make no specific recommendations on anticoagulation for people with TAF. Experts recommend

Article Type:
Research Article
Collections:
Cardiovascular
DOI:
https://doi.org/10.1530/EC-22-0166
Volume/Issue:
Volume 11: Issue 5
Open access
Mírian Romitti Thyroid Unit, Endocrine Division, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

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Vitor C Fabris Gynecological Endocrinology Unit, Endocrine Division, Hospital de Clínicas de Porto Alegre, and Department of Physiology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

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Patricia K Ziegelmann Postgraduate Program in Epidemiology and Department of Statistics, Institute of Mathematics, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

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Ana Luiza Maia Thyroid Unit, Endocrine Division, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

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Poli Mara Spritzer Gynecological Endocrinology Unit, Endocrine Division, Hospital de Clínicas de Porto Alegre, and Department of Physiology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil

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of thyroiditis among women with PCOS. The results suggested a higher incidence of thyroiditis in PCOS than those in controls ( 31 ). Therefore, the aim of this systematic review and meta-analysis was to summarize and update the available evidence

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0309
Volume/Issue:
Volume 7: Issue 11
Open access
Milou Cecilia Madsen Department of Internal Medicine and Center of Expertise on Gender Dysphoria, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

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Martin den Heijer Department of Internal Medicine and Center of Expertise on Gender Dysphoria, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands

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Claudia Pees Walaeus Library, Leiden University Medical Center, Leiden, the Netherlands

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Nienke R Biermasz Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands

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Leontine E H Bakker Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands

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and are included in the international guidelines ( 2 , 3 , 12 , 13 , 14 , 15 , 16 ). This systematic review aims to review current literature on the difference between the different treatment options in adult hypogonadal and transgender males

Article Type:
Review Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-22-0112
Volume/Issue:
Volume 11: Issue 8
Open access
Taís S Assmann Endocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil
Postgraduation Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

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Mariana Recamonde-Mendoza Institute of Informatics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

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Bianca M De Souza Endocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil
Postgraduation Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

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Daisy Crispim Endocrine Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil
Postgraduation Program in Medical Sciences: Endocrinology, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil

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, to further investigate which miRNAs may be used as new potential biomarkers of T1DM, we performed a systematic review of the literature on the subject. Additionally, bioinformatic analyses were performed to investigate the regulatory and functional

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0248
Volume/Issue:
Volume 6: Issue 8
Open access
Caihong Xin Department of Endocrinology and Metabolism, The Fourth People’s Hospital of Shenyang, Shenyang, P.R. China

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Lijuan Niu Department of Endocrinology and Metabolism, The First Affiliated Hospital of Soochow University, Suzhou, P.R. China

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Huaying Fan Department of Endocrinology and Metabolism, The First Affiliated Hospital of Soochow University, Suzhou, P.R. China

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Jing Xie Department of Endocrinology and Metabolism, The First Affiliated Hospital of Soochow University, Suzhou, P.R. China

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Xin Sun Department of Endocrinology and Metabolism, The First Affiliated Hospital of Soochow University, Suzhou, P.R. China

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between thyroid disease and sarcoidosis. Conclusion This systematic review is the first to evaluate the pooled incidence of thyroid disease in sarcoidosis patients. The results of our meta-analysis support the hypothesis that the prevalence of

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-23-0157
Volume/Issue:
Volume 12: Issue 9
Open access
Nidan Qiao Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
Neuroendocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA

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machine learning studies ( 3 ). With the expansion of machine learning in medical studies, the applications in real clinical decision making are booming, which requires both robustness and generalizability ( 4 , 5 ). This systematic review aims to

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0156
Volume/Issue:
Volume 8: Issue 7
Open access