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patients. Although, the acute side effects of combination chemotherapy and CCRT are well defined, the late adverse effects have not been considered after adjuvant anticancer treatments. The long-term toxicity of surgical menopause and anticancer
Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA
Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, Oregon, USA
Department of Physiology & Pharmacology, Oregon Health & Science University, Portland, Oregon, USA
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Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA
Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon, USA
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supplementation. In the present study, we examined these issues using a nonhuman primate model of surgical menopause, in which old rhesus macaques were OvH and fed a WSD for 2 years. Although expected changes in body weight, level of activity and circulating
K.G. Jebsen Center for Autoimmune Disorders, University of Bergen, Bergen, Norway
Department of Medicine, Haukeland University Hospital, Bergen, Norway
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Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway
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K.G. Jebsen Center for Autoimmune Disorders, University of Bergen, Bergen, Norway
Department of Medicine, Haukeland University Hospital, Bergen, Norway
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Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Stockholm, Sweden
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Department of Sleep, Landspitali University Hospital Reykjavík, Reykjavik, Iceland
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Allergy and Lung Health Unit, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria, Australia
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Albacete Faculty of Medicine, Castilla-La Mancha University, Albacete, Spain
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The National Research Center for the Working Environment, Copenhagen, Denmark
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K.G. Jebsen Center for Autoimmune Disorders, University of Bergen, Bergen, Norway
Department of Medicine, Haukeland University Hospital, Bergen, Norway
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, 21% (260/1253) stated surgical reasons and <1% (5/1253)) non-ovarian reasons for menopause. Premature menopause The prevalence of premature menopause was 2.8% (195/6870. Among the women with premature menopause, 47% (91/195) had iatrogenic
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increased risk for CVD for natural and surgical premature menopause (<40 years) compared with menopause at an age >40 years (HR 1.36, 95% CI 1.19–1.56 and 1.87, 95% CI 1.36–2.58, respectively, after adjustment for conventional CVD risk factors and the use of
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availability of follow-up data. For each case, detailed clinicopathological characteristics including age, menopausal status, tumor size, nuclear grade, lymph node metastasis (LNM) and AJCC TNM stage were routinely abstracted from the medical record and are
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Department of Surgery, Warsaw Medical University, Warsaw, Poland
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aggressive therapy must often be considered utilising surgical and/or medical modalities. Right hemicolectomy is advocated as the standard surgical approach by the European Neuroendocrine Tumor Society (ENETS) and North American Neuroendocrine Tumor Society
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(21%) chose to maintain treatment and 27 (9%) chose to discontinue medication after menopause. Regarding macroprolactinomas, 173 (60%) of physicians recommended maintenance therapy, 89 (31%) recommended withdrawal of medication 2–3 years after
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Department of Obstetrics and Gynecology, University of Oulu and Oulu University Hospital, Medical Research Center, PEDEGO Research Unit, Oulu, Finland
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women who have undergone iatrogenic, surgical menopause in the form of bilateral oophorectomy. Long-term health implications of non-iatrogenic POI may be different due to the more gradual and fluctuating course of the disease. The inactivating FSH
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obesity on the prognosis of breast cancer is magnified in menopausal women and those with suppressed ovarian function. Importantly, the prognosis of menopausal patients with breast cancer is affected by obesity; this might arise from elevated aromatase in
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Introduction Management of young patients with endocrine-sensitive breast cancer is challenging, due to various treatment regimens that may cause menopausal symptoms or infertility, and most importantly, affect the prognosis of the disease