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Morten Winkler Møller Department of Neurosurgery, Odense University Hospital, Odense C, Denmark
Clinical Institute, University of Southern Denmark, Odense C, Denmark

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Marianne Skovsager Andersen Clinical Institute, University of Southern Denmark, Odense C, Denmark
Department of Endocrinology, Odense University Hospital, Odense C, Denmark

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Christian Bonde Pedersen Department of Neurosurgery, Odense University Hospital, Odense C, Denmark
Clinical Institute, University of Southern Denmark, Odense C, Denmark

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Bjarne Winther Kristensen Clinical Institute, University of Southern Denmark, Odense C, Denmark
Department of Pathology, Odense University Hospital, Odense C, Denmark

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Frantz Rom Poulsen Department of Neurosurgery, Odense University Hospital, Odense C, Denmark
Clinical Institute, University of Southern Denmark, Odense C, Denmark

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). For other PAs, except prolactinomas, surgery is the first choice of treatment. The primary surgical technique has been transsphenoidal surgery since Hardy introduced surgical microscopes in 1962 ( 9 ). Further development of this technique has improved

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0140
Volume/Issue:
Volume 7: Issue 7
Open access
Chao-bin He Department of Hepatobiliary and Pancreatic Surgery, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China

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Yu Zhang State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, People’s Republic of China

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Zhi-yuan Cai Department of Hepatobiliary and Pancreatic Surgery, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China

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Xiao-jun Lin Department of Hepatobiliary and Pancreatic Surgery, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, People’s Republic of China

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small numbers of included patients and the absence of unified standards, it is still unclear how much benefit can be obtained from surgery for patients with metastatic PNETs. PNET is a heterogeneous group of tumors and differs both biologically and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0485
Volume/Issue:
Volume 8: Issue 3
Open access
Jülide Durmuşoğlu Division of Endocrinology, Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands

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Henri J L M Timmers Division of Endocrinology, Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands

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Pepijn van Houten Division of Endocrinology, Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands

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Johan F Langenhuijsen Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands

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Ad R M M Hermus Division of Endocrinology, Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands

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Annenienke C van de Ven Division of Endocrinology, Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands

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incidence of VTE in patients with ACC since malignancy, abdominal surgery and chemotherapy are associated with VTE ( 13 , 14 ). In addition, hormonal excess of cortisol and androgens/estrogens are also associated with an increased risk of VTE ( 15 , 16

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0299
Volume/Issue:
Volume 9: Issue 9
Open access
Eeva M Ryhänen
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Ilkka Heiskanen
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Harri Sintonen Endocrinology, Department of Public Health, Group Administration, Helsinki University Hospital, University of Eastern Finland, Abdominal Center, University of Helsinki and Helsinki University Hospital, Post Box 340, FI-00290 Helsinki, Finland

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Matti J Välimäki
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Risto P Roine Endocrinology, Department of Public Health, Group Administration, Helsinki University Hospital, University of Eastern Finland, Abdominal Center, University of Helsinki and Helsinki University Hospital, Post Box 340, FI-00290 Helsinki, Finland
Endocrinology, Department of Public Health, Group Administration, Helsinki University Hospital, University of Eastern Finland, Abdominal Center, University of Helsinki and Helsinki University Hospital, Post Box 340, FI-00290 Helsinki, Finland
Endocrinology, Department of Public Health, Group Administration, Helsinki University Hospital, University of Eastern Finland, Abdominal Center, University of Helsinki and Helsinki University Hospital, Post Box 340, FI-00290 Helsinki, Finland

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Camilla Schalin-Jäntti
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Introduction The clinical presentation of primary hyperparathyroidism (PHPT) has changed during the last decades. The majority of patients are nowadays asymptomatic with only mild hypercalcaemia (1, 2, 3) . Surgery offers the only opportunity for

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-15-0053
Volume/Issue:
Volume 4: Issue 3
Open access
Agnieszka Bogusz Department of Pediatrics and Pediatric Hematology/Oncology, University Children’s Hospital, Klinikum Oldenburg AöR, Oldenburg, Germany
Department of Endocrinology and Diabetology, The Children’s Memorial Health Institute, Warsaw, Poland

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Svenja Boekhoff Department of Pediatrics and Pediatric Hematology/Oncology, University Children’s Hospital, Klinikum Oldenburg AöR, Oldenburg, Germany

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Monika Warmuth-Metz Department of Neuroradiology, University Hospital, Würzburg, Germany

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Gabriele Calaminus Department of Pediatric Oncology and Hematology, University Hospital, Bonn, Germany

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Maria Eveslage Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany

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Hermann L Müller Department of Pediatrics and Pediatric Hematology/Oncology, University Children’s Hospital, Klinikum Oldenburg AöR, Oldenburg, Germany

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 + pHL significantly decreased between 1 and 3 years after surgery for the PEDQOL domains social functionality friends ( P  = 0.050) and family ( P  = 0.016). Decreased QoL was observed during further follow-up in CP with a + pHL when compared with CP

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0074
Volume/Issue:
Volume 8: Issue 5
Open access
Amir H Zamanipoor Najafabadi Department of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands
Department of Medicine, Division of Endocrinology and Centre for Endocrine Tumors, Leiden University Medical Centre, Leiden, The Netherlands
Department of Neurosurgery, University Neurosurgical Centre Holland (UNCH), Leiden University Medical Centre, Haaglanden Medical Centre and Haga Teaching Hospitals, Leiden and The Hague, The Netherlands

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Merel van der Meulen Department of Medicine, Division of Endocrinology and Centre for Endocrine Tumors, Leiden University Medical Centre, Leiden, The Netherlands

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Ana Luisa Priego Zurita Department of Medicine, Division of Endocrinology and Centre for Endocrine Tumors, Leiden University Medical Centre, Leiden, The Netherlands

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S Faisal Ahmed Chair of Work Package of E-Health & ICT of Endo-ERN, Developmental Endocrinology Research Group, School of Medicine, Dentistry & Nursing, University of Glasgow and Office for Rare Conditions, Royal Hospital for Children & Queen Elizabeth University Hospital, Glasgow, UK

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Wouter R van Furth Department of Ophthalmology, Leiden University Medical Center, Leiden, The Netherlands

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Evangelia Charmandari Pediatric Chair Main Thematic Group 6 Pituitary of Endo-ERN, Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, National and Kapodistrian University of Athens Medical School, ‘Aghia Sophia’ Children’s Hospital, Athens, Greece

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Olaf Hiort Pediatric Chair and Deputy Coordinator of Endo-ERN, Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University of Lübeck, Lübeck, Germany

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Alberto M Pereira Adult Chair and Coordinator of Endo-ERN, Department of Endocrinology and Metabolism, Amsterdam University Medical Center, Amsterdam, The Netherlands

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Mehul Dattani London Centre for Pediatric Endocrinology and Diabetes at Great Ormond Street Children's Hospital and University College London Hospitals, London, UK

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Diana Vitali SOD ITALIA (Italian Organization for Septo Optic Dysplasia and other Neuroendocrine Disorders), European Patient Advocacy Group, Rome, Italy

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Johan P de Graaf Dutch Pituitary Foundation, European Patient Advocacy Group, Nijkerk, The Netherlands

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Nienke R Biermasz Adult Chair Main Thematic Group 6 Pituitary of Endo-ERN, Department of Medicine, Division of Endocrinology and Centre for Endocrine Tumors, Leiden University Medical Centre, Leiden, The Netherlands

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preferably organized in high-volume reference centers around multidisciplinary teams with accessibility to neurosurgical care, as current guidelines recommend transsphenoidal surgery as first-line treatment for the majority of adenoma subtypes, although many

Article Type:
Review Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0349
Volume/Issue:
Volume 12: Issue 1
Open access
Rasmus Reinke Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, Aarhus, Denmark

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Stefano Christian Londero Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, Aarhus, Denmark

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Martin Almquist Department of Surgery, Lund University Hospital, Lund, Sweden

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Lars Rejnmark Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Lars Rolighed Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, Aarhus, Denmark

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, Denmark, TT was performed by surgeons who did and who did not also perform parathyroid surgery. Our own data showed a higher rate of permanent hypoPT after TT, especially for Graves’ disease (GD), when performed by surgeons who did not also perform

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-23-0198
Volume/Issue:
Volume 12: Issue 9
Open access
Luchuan Li Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China

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Baoyuan Li Department of Thyroid Surgery, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China

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Bin Lv Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China

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Weili Liang Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China

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Binbin Zhang Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China

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Qingdong Zeng Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China

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Andrew G Turner Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia

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Lei Sheng Department of Thyroid Surgery, General Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, China

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between 2010 and 2020. Materials and Methods Patients Clinical data were collected from patients with PHPT undergoing surgery in two large tertiary medical centers (Qilu hospital of Shandong University and the Affiliated Yantai Yuhuangding

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0217
Volume/Issue:
Volume 10: Issue 8
Open access
Raluca Maria Furnica Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

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Muhammad Muddaththir Dusoruth Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

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Alexandre Persu Department of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

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Damien Gruson Department of Biology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

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Michel Mourad Endocrine Surgery, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

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Dominique Maiter Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium

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testing, as these tumours carry a very high rate of germline mutations, up to 35–40% in recent series ( 9 , 10 , 11 ). Surgery represents the primary treatment of PPGL ( 2 , 3 ). Thanks to improvements in medical treatment, anaesthesia and surgical

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0537
Volume/Issue:
Volume 10: Issue 1
Open access
Nidan Qiao Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China
Harvard Medical School, Boston, Massachusetts, USA

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Introduction Cushing’s disease (CD) is a subtype of pituitary adenoma with hypercortisolism and presents a particular challenge to neurosurgeons. Transsphenoidal surgery (TS) has long been the standard of care for patients with CD ( 1 , 2

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-17-0312
Volume/Issue:
Volume 7: Issue 1
Open access