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Katica Bajuk Studen Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

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Simona Gaberšček Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

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Edvard Pirnat Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia

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Nataša Bedernjak Bajuk Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia

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Andreja Vendramin Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia

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Vito Majcen Department of Nuclear Medicine, SB Celje, Celje, Slovenia

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Katja Zaletel Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

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Introduction Subacute thyroiditis (ST), also called subacute granulomatous or de Quervain’s thyroiditis, is a transient inflammatory thyroid disease ( 1 , 2 ). The diagnosis of ST is based on medical history, physical examination, thyroid

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Chenjia Tang Department of Endocrinology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China

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Yanting Dong Department of Endocrinology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China
Department of Endocrinology, Suichang County Hospital of Traditional Chinese Medicine, Lishui, China

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Lusi Lu Department of Endocrinology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China

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Nan Zhang Department of Endocrinology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China

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Introduction Subacute thyroiditis (SAT), also known as De Quervain’s thyroiditis, giant cell thyroiditis, or granulomatous thyroiditis, is an inflammatory thyroid disease, probably associated with viral infection ( 1 ). It is often

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Paraskevi Kazakou Diabetes Centre, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Stavroula A Paschou Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Theodora Psaltopoulou Unit of Hematology and Oncology, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Maria Gavriatopoulou Unit of Hematology and Oncology, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Eleni Korompoki Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Katerina Stefanaki Endocrine Unit, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Fotini Kanouta Department of Endocrinology, Alexandra Hospital, Athens, Greece

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Georgia N Kassi Department of Endocrinology, Alexandra Hospital, Athens, Greece

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Meletios-Athanasios Dimopoulos Unit of Hematology and Oncology, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Asimina Mitrakou Diabetes Centre, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece

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hyponatremia (75) No data so far Possible inappropriate antidiuretic hormone secretion syndrome (75) Thyroid Low T3 concentrations (77, 78, 79, 80) Thyrotoxicosis (78, 81) Subacute thyroiditis (78, 82, 83, 84, 85, 86) Low T3 concentrations (77, 78

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Dimitra Argyro Vassiliadi Department of Endocrinology Diabetes and Metabolism, National Expertise Center for Rare Endocrine Diseases, Evangelismos Hospital, Athens, Greece

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Ioannis Ilias Department of Endocrinology Diabetes and Metabolism, Elena Venizelou Hospital, Elena Venizelou Square, Athens, Greece

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Maria Pratikaki 1st Department of Critical Care & Pulmonary Services, Medical School National & Kapodistrian, Evangelismos Hospital, University of Athens, Athens, Greece

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Edison Jahaj 1st Department of Critical Care & Pulmonary Services, Medical School National & Kapodistrian, Evangelismos Hospital, University of Athens, Athens, Greece

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Alice G Vassiliou 1st Department of Critical Care, GP Livanos & M Simou Laboratories, Medical School National & Kapodistrian, Evangelismos Hospital, University of Athens, Athens, Greece

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Maria Detsika 1st Department of Critical Care, GP Livanos & M Simou Laboratories, Medical School National & Kapodistrian, Evangelismos Hospital, University of Athens, Athens, Greece

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Kleio Ampelakiotou Department of Immunology and Histocompatibility Evangelismos Hospital, Athens, Greece

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Marina Koulenti Department of Endocrinology Diabetes and Metabolism, National Expertise Center for Rare Endocrine Diseases, Evangelismos Hospital, Athens, Greece

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Konstantinos N Manolopoulos Department of Endocrinology Diabetes and Metabolism, National Expertise Center for Rare Endocrine Diseases, Evangelismos Hospital, Athens, Greece

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Stamatis Tsipilis 1st Department of Critical Care & Pulmonary Services, Medical School National & Kapodistrian, Evangelismos Hospital, University of Athens, Athens, Greece

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Evdokia Gavrielatou 1st Department of Critical Care & Pulmonary Services, Medical School National & Kapodistrian, Evangelismos Hospital, University of Athens, Athens, Greece

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Aristidis Diamantopoulos Department of Endocrinology Diabetes and Metabolism, National Expertise Center for Rare Endocrine Diseases, Evangelismos Hospital, Athens, Greece

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Alexandros Zacharis 1st Department of Critical Care & Pulmonary Services, Medical School National & Kapodistrian, Evangelismos Hospital, University of Athens, Athens, Greece

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Nicolaos Athanasiou 1st Department of Critical Care & Pulmonary Services, Medical School National & Kapodistrian, Evangelismos Hospital, University of Athens, Athens, Greece

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Stylianos Orfanos 2nd Department of Critical Care Medical School National & Kapodistrian University of Athens Attikon University Hospital, Athens-Haidari, Greece

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Anastasia Kotanidou 1st Department of Critical Care & Pulmonary Services, Medical School National & Kapodistrian, Evangelismos Hospital, University of Athens, Athens, Greece

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Stylianos Tsagarakis Department of Endocrinology Diabetes and Metabolism, National Expertise Center for Rare Endocrine Diseases, Evangelismos Hospital, Athens, Greece

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Ioanna Dimopoulou 1st Department of Critical Care & Pulmonary Services, Medical School National & Kapodistrian, Evangelismos Hospital, University of Athens, Athens, Greece

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( 5 ). Pathological studies failed to show direct involvement of thyroid tissue ( 6 ). Reports describing patients with thyrotoxicosis attributed to SARS-CoV-2-related subacute thyroiditis ( 7 , 8 , 9 , 10 , 11 , 12 , 13 ) enforced the

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Clara Lundetoft Clausen Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark

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Åse Krogh Rasmussen Department of Medical Endocrinology and Metabolism, Copenhagen University Hospital, Copenhagen, Denmark

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Trine Holm Johannsen Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark

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Linda Maria Hilsted Department of Clinical Biochemistry, Copenhagen University Hospital, Copenhagen, Denmark

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Niels Erik Skakkebæk Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark

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Pal Bela Szecsi Department of Clinical Biochemistry, Holbæk Hospital, Holbæk, Denmark

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Lise Pedersen Department of Clinical Biochemistry, Holbæk Hospital, Holbæk, Denmark

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Thomas Benfield Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital, Hvidovre, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Anders Juul Department of Growth and Reproduction, Copenhagen University Hospital, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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, which is a non-standard measure for thyroid function. SARS-CoV-2 may like other viruses directly affect thyroid tissue and lead to subacute thyroiditis (de Quervain thyroiditis). It has been suggested that SARS-CoV-2 may induce destructive thyroiditis

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Aleksandra Krygier Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Ewelina Szczepanek-Parulska Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Dorota Filipowicz Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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hepcidin serum level is high at the diagnosis of other thyroid inflammatory diseases, subacute thyroiditis (SAT) and Hashimoto’s thyroiditis and significantly decreases after treatment. The observed changes in hepcidin concentration take place along with

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Ewa Stogowska Department of Internal Medicine and Metabolic Diseases, Medical University of Bialystok, Bialystok, Poland

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Karol Adam Kamiński Department of Population Medicine and Civilization Diseases Prevention, Medical University of Bialystok, Bialystok, Poland

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Bartosz Ziółko Techmo, Kraków, Poland

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Irina Kowalska Department of Internal Medicine and Metabolic Diseases, Medical University of Bialystok, Bialystok, Poland

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conducted by Hamdan et al. ( 35 ), where the acoustic and perceptual parameters were compared between the patients with thyroiditis and healthy subjects. In this research, a study group comprised patients affected by subacute thyroiditis and autoimmune

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Aditya Dutta Institute of Endocrinology and Diabetes, Max Healthcare, Saket, New Delhi, India

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Ganesh Jevalikar Institute of Endocrinology and Diabetes, Max Healthcare, Saket, New Delhi, India

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Rutuja Sharma Institute of Endocrinology and Diabetes, Max Healthcare, Saket, New Delhi, India

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Khalid J Farooqui Institute of Endocrinology and Diabetes, Max Healthcare, Saket, New Delhi, India

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Shama Mahendru Institute of Endocrinology and Diabetes, Max Healthcare, Saket, New Delhi, India

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Arun Dewan Institute of Internal Medicine, Max Healthcare, Saket, New Delhi, India

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Sandeep Bhudiraja Institute of Internal Medicine, Max Healthcare, Saket, New Delhi, India

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Ambrish Mithal Institute of Endocrinology and Diabetes, Max Healthcare, Saket, New Delhi, India

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Magri F Latrofa F Chiovato L . Detection of SARS-COV-2 receptor ACE-2 mRNA in thyroid cells: a clue for COVID-19-related subacute thyroiditis . Journal of Endocrinological Investigation 2021 44 1085 – 1090 . ( https://doi.org/10.1007/s40618

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Simona Censi Endocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy

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Laura Salmaso Clinical Governance Unit, Azienda Zero, Veneto Region, Italy

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Filippo Ceccato Endocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy

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Jacopo Manso Endocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy
Pediatric Endocrinology Unit, Department of Women's and Children's Health, Padua University Hospital, Padova, Italy

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Ugo Fedeli Clinical Governance Unit, Azienda Zero, Veneto Region, Italy

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Mario Saia Clinical Governance Unit, Azienda Zero, Veneto Region, Italy

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Caterina Mian Endocrinology Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy

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, mainly GD and subacute thyroiditis have been described. GD has been reported to occur more frequently with mRNA-based vaccines than with the adenovirus-vectored (while inactivated vaccines seem to be not associated), after the first or second dose and

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Giorgio Grani Department of Internal Medicine and Medical Specialties, ‘Sapienza’ University of Rome, Rome, Italy

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Livia Lamartina Department of Internal Medicine and Medical Specialties, ‘Sapienza’ University of Rome, Rome, Italy

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Vito Cantisani UOS Innovazioni Diagnostiche e Ultrasonografiche, Azienda Ospedaliera Universitaria Policlinico Umberto I, ‘Sapienza’ University of Rome, Rome, Italy

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Marianna Maranghi Department of Internal Medicine and Medical Specialties, ‘Sapienza’ University of Rome, Rome, Italy

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Piernatale Lucia Department of Internal Medicine and Medical Specialties, ‘Sapienza’ University of Rome, Rome, Italy

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Cosimo Durante Department of Internal Medicine and Medical Specialties, ‘Sapienza’ University of Rome, Rome, Italy

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thyroid autoimmunity and subacute thyroiditis. Enrolled patients were followed with yearly clinical and US evaluations. For the purposes of the present study, the images of the 1055 nodules (at various follow-up points) were converted to and stored as

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