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S U Jayasinghe, S J Torres, C A Nowson, A J Tilbrook, and A I Turner

Introduction The ability of stress to impair physiological processes such as growth, reproduction and immune competence and its association with diseases such as cardiovascular disease, type 2 diabetes and anxiety and depression are well known (1

Open access

Mardia López-Alarcón, Jessie N Zurita-Cruz, Alonso Torres-Rodríguez, Karla Bedia-Mejía, Manuel Pérez-Güemez, Leonel Jaramillo-Villanueva, Mario E Rendón-Macías, Jose R Fernández, and Patricia Martínez-Maroñas

Introduction Pediatric obesity is a pathological condition that leads to important health consequences in childhood and later life ( 1 , 2 ). In addition to diet and sedentary behavior, psychological factors such as stress, depression, and

Open access

Rachel K Rowe, Benjamin M Rumney, Hazel G May, Paska Permana, P David Adelson, S Mitchell Harman, Jonathan Lifshitz, and Theresa C Thomas

injury severity spectrum ( 15 ). Injury-induced endocrine dysfunction can be concomitant with and potentially augment clinical symptoms commonly associated with postconcussive syndrome and post-traumatic stress disorder (PTSD) ( 22 , 29 ). While the

Open access

I Azzam, S Gilad, R Limor, N Stern, and Y Greenman

( 3 ), ghrelin was found to be involved in a myriad of additional physiologic functions ( 4 , 5 , 6 , 7 ). Ghrelin plays an important role in the activation of central pathways mediating stress-induced food reward behavior ( 8 , 9 , 10 , 11 ) and

Open access

Carlo Cinque, Manuela Zinni, Anna Rita Zuena, Chiara Giuli, Sebastiano G Alemà, Assia Catalani, Paola Casolini, and Roberto Cozzolino

Introduction Stress events can have an important impact on both physiological and psychological parameters. For this reason, assessing animals’ stress physiology is essential to understand and improve animal welfare, health and reproduction

Open access

N Bergmann, F Gyntelberg, and J Faber

etiology seems multifactorial, which calls for new areas of prevention and intervention. One potential risk factor for the development of MES is chronic psychosocial stress, in the following referred to as stress. In general it is accepted to divide the

Open access

Bo Zhu, Yumei Chen, Fang Xu, Xiaolu Shen, Xuanyu Chen, Jieqiang Lv, and Songying Zhang

etiology of PCOS is complex and unclear, recent studies reveal that androgens excess and endoplasmic reticulum (ER) stress play important roles in the progression and pathogenesis of PCOS ( 7 , 8 , 9 ). Clinical studies showed that hyperandrogenism is

Open access

Ling Zhou, Ruixue Zhang, Shuangyan Yang, Yaguang Zhang, and Dandan Shi

-IV could effectively ameliorate GDM in genetic mouse model of GDM by inhibiting NLRP3 inflammasome in the pancreas ( 13 ). We also found that AS-IV remarkably reduced hepatic gluconeogenesis, hepatic inflammation and oxidative stress to alleviate GDM in

Open access

Maria Giannakou, Katerina Saltiki, Emily Mantzou, Eleni Loukari, Georgios Philippou, Konstantinos Terzidis, Charalampos Stavrianos, Miltiades Kyprianou, Theodora Psaltopoulou, Kalliopi Karatzi, and Maria Alevizaki

, thioredoxin system) and nonenzymatic (i.e. b-carotene, glutathione vitamin E, vitamin C, vitamin A) ( 1 , 2 , 3 , 4 ). Disturbance of the balance between oxidants and antioxidants in favor of the oxidants results in oxidative stress ( 1 , 2 , 3 , 4

Open access

T S Nilsen, L Thorsen, C Kirkegaard, I Ugelstad, S D Fosså, and T Raastad

is increased when muscle cells are exposed to several types of stressors ( 18 , 19 ) and increasing age, at least for the larger HSPs ( 20 ). This would, in theory, preserve muscle mass, by stabilisation of stressed and damaged proteins ( 21 ). No