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Earn H Gan, Wendy Robson, Peter Murphy, Robert Pickard, Simon Pearce and Rachel Oldershaw

capacity of rodent adrenal capsule nearly 80 years ago ( 4 ), the exact in vivo identity of adrenocortical stem cells (ACSCs) remains elusive. Adult mesenchymal stromal or stem cells (MSCs) have drawn significant interest among researchers in the stem

Open access

Melissa Braga, Zena Simmons, Keith C Norris, Monica G Ferrini and Jorge N Artaza

muscle stem cells’, have a remarkable ability to regenerate after muscle injury and are responsible for compensation of muscle turnover caused by daily wear and tear. In this study, we expand our previous results and conclusions ( 11 , 12 ) by now

Open access

Luminita Nicoleta Cima, Anca Colita and Simona Fica

Introduction Hematopoietic stem cell transplantation (HSCT) is increasingly used for the treatment of both malignant and nonmalignant diseases. Survival after autologous/allogeneic HSCT is no longer the highest concern, as many patients

Open access

Jan-Bernd Stukenborg, Kirsi Jahnukainen, Marsida Hutka and Rod T Mitchell

Introduction Fertility in males is dependent on the presence of a germ cell population that is capable of developing into sperm in adulthood. However, the ability of spermatogonial stem cells (SSC) to give rise to sperm is dependent on the

Open access

Monia Cito, Silvia Pellegrini, Lorenzo Piemonti and Valeria Sordi

variability of isolated human islets and the need for lifelong immunosuppression. Different approaches using stem cells to support islet survival and function are being explored in preclinical and clinical settings ( 5 ). Now, the most advanced strategies to

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Ashley N Reeb, Andrea Ziegler and Reigh-Yi Lin

THJ-16T. In these studies, we achieved a 100% tumor take rate ( 11 , 13 ). We have also used NSG mice to confirm the presence of a rare subpopulation of cancer stem cells in the ATC cell lines ( 14 ). In this study, all three human FTC cell lines

Open access

Masatada Watanabe, Shuji Ohno and Hiroshi Wachi

mechanisms between cells of hematopoietic stem cell origin and cells of mesenchymal stem cell origin. This difference might provide a basis for new tissue-specific or cell-specific pharmacotherapeutic utilization of glucocorticoids, β-agonists and β

Open access

Juan Carlos Juárez-Cruz, Miriam Daniela Zuñiga-Eulogio, Monserrat Olea-Flores, Eduardo Castañeda-Saucedo, Miguel Ángel Mendoza-Catalán, Carlos Ortuño-Pineda, Ma Elena Moreno-Godínez, Sócrates Villegas-Comonfort, Teresita Padilla-Benavides and Napoleón Navarro-Tito

and therapeutic target of leptin signaling in breast cancer and cancer stem cells . Biochimica et Biophysica Acta 2013 207 – 222 . ( https://doi.org/10.1016/j.bbcan.2012.01.002 ) 12 Laudisio D Muscogiuri G Barrea L Savastano S Colao A

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Agnieszka Kosowska, Enrique Gallego-Colon, Wojciech Garczorz, Agnieszka Kłych-Ratuszny, Mohammad Reza F Aghdam, Michał Woz´niak, Andrzej Witek, Agnieszka Wróblewska-Czech, Anna Cygal, Jerzy Wojnar and Tomasz Francuz

. Angiogenesis in epithelian ovarian cancer . Molecular Pathology  2002 55 348 – 359 . 10.1136/mp.55.6.348 39 Markowska A Sajdak S Markowska J Huczynski A . Angiogenesis and cancer stem cells: new perspectives on therapy of ovarian cancer

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Erika Peverelli, Federica Ermetici, Sabrina Corbetta, Ettore Gozzini, Laura Avagliano, Marco A Zappa, Gaetano Bulfamante, Paolo Beck-Peccoz, Anna Spada and Giovanna Mantovani

studies demonstrating that embryonic stem cells lacking PPARγ do not contribute to fat formation (28, 29) and that the abolishment of the expression of PPARγ at the adipose tissue level prevents WAT development (30, 31, 32) . In accordance with this