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COC users report decreased sexual desire ( 2 ). At present, despite the bulk of literature, only two randomised placebo-controlled trials have investigated the causal influence of COCs on sexual function ( 3 , 4 ). Both of these studies evaluated a
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Introduction Over the past decades, research attention has been increasingly paid to the examination of the neurobiological component of sexual function. Female sexual desire and arousal have been shown to have a heritable component of
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been poor responders to LSM, by means of reversal of FH and WR. The primary outcome measures were changes in testosterone, sexual function and gonadotropins. The secondary outcomes were measures of obesity and metabolic profile. Materials and
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imprinted function. For example, perinatal testosterone or its androgen/estrogen metabolites are required to permanently 'wire' or imprint the male brain to exclusively express masculine sexual behavior. However, the brain has to be stimulated or activated
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Department of Obstetrics and Gynecology, University of Oulu and Oulu University Hospital, Medical Research Center, PEDEGO Research Unit, Oulu, Finland
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due to CVD, osteoporosis and fractures. In addition, impairment of cognitive functions, dementia, Parkinsonism, and reduced sexual function and psychological well-being have been reported ( 12 ). Most of the evidence comes from observational studies of
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clownfish is a protandrous hermaphroditic teleost whose sexual development can be regulated by its social status ( 29 ). In general, there is only one dominant female individual and one subdominant male with reproductive function in the group, while non
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Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
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-related bias ( 16 ). Female Sexual Function Index (FSFI) assesses the domains of sexual function: desire, arousal, lubrication, orgasm, satisfaction, and pain and provides a score regarding sexual function. Total score achievable is 36, a lower FSFI score
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peripheral leptin has not been compared in males and females, a comparison which may allow the examination of possible sexual dimorphism of leptin functions. Despite the large volume of research on leptin, its total distribution is not well characterised
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Endocrinology, Department of Public Health, Group Administration, Helsinki University Hospital, University of Eastern Finland, Abdominal Center, University of Helsinki and Helsinki University Hospital, Post Box 340, FI-00290 Helsinki, Finland
Endocrinology, Department of Public Health, Group Administration, Helsinki University Hospital, University of Eastern Finland, Abdominal Center, University of Helsinki and Helsinki University Hospital, Post Box 340, FI-00290 Helsinki, Finland
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, excretion, usual activities, mental function, discomfort and symptoms, depression, distress, vitality, and sexual activity) has five levels and the respondent chooses the level best describing her/his current health status for each dimension. The 15D score
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Division of Interventional Cognitive Neurology, Department of Neurology, Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
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, 4 ); however, the underlying pathophysiology is not fully clarified. Animal data emphasize the importance of a balanced MR/glucocorticoid receptor (GR) system for cognitive functions ( 5 ) and support the role of MR in memory functions. Furthermore