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Bledar Daka, Thord Rosen, Per Anders Jansson, Lennart Råstam, Charlotte A Larsson and Ulf Lindblad

Introduction Sex hormone-binding globulin (SHBG) is a circulating plasma globulin binding sex hormones, both oestradiol and testosterone and is produced primarily by the liver. In two recent studies, SHBG could predict type 2 diabetes (T2D) in

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Shenglong Le, Leiting Xu, Moritz Schumann, Na Wu, Timo Törmäkangas, Markku Alén, Sulin Cheng and Petri Wiklund

Introduction Sex steroids are important regulators of pubertal development and their biological action is governed by sex hormone-binding globulin (SHBG) ( 1 ). Serum SHBG levels rise from birth to early childhood, then decline in early

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Florian Schederecker, Alexander Cecil, Cornelia Prehn, Jana Nano, Wolfgang Koenig, Jerzy Adamski, Tanja Zeller, Annette Peters and Barbara Thorand

, justifying our main analysis. Figure 1 Splines of SHBG and androgen concentrations: all-cause mortality in men. SHBG, sex hormone-binding globulin; TT, total testosterone; cFT, calculated free testosterone; DHT, dihydrotestoterone; E2, Estradiol

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Yael Sofer, Nava Nevo, Michal Vechoropoulos, Gabi Shefer, Etty Osher, Nathan Landis, Karen Tordjman, Geoffrey L Hammond and Naftali Stern

work was supported by the Sagol Foundation for the Metabolic Syndrome Research Center at TASMC and by Dr Sofer’s TASMC research grant for excellence in research. References 1 Hammond GL. Diverse roles for sex hormone-binding globulin in

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M Boering, P R van Dijk, S J J Logtenberg, K H Groenier, B H R Wolffenbuttel, R O B Gans, N Kleefstra and H J G Bilo

suggested to influence several extra-glycemic, metabolic, and endocrinological parameters, such as the sex hormone-binding globulin (SHBG). SHBG is a glycoprotein produced in the liver, which regulates the bioavailability of sex steroids for target tissues

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Kristin Ottarsdottir, Margareta Hellgren, David Bock, Anna G Nilsson and Bledar Daka

Introduction Sex hormone-binding globulin is a glycoprotein traditionally known as a carrier protein for sex hormones in both men and women. Cross-sectional and prospective epidemiological cohort studies have demonstrated that low levels of

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M P Schuijt, C G J Sweep, R van der Steen, A J Olthaar, N M M L Stikkelbroeck, H A Ross and A E van Herwaarden

and Metabolism 1981 53 58 – 68 . ( ) 10.1210/jcem-53-1-58 16 Hong H Branham WS Ng HW Moland CL Dial SL Fang H Perkins R Sheehan D Tong W . Human sex hormone-binding globulin binding affinities of 125

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Angela Köninger, Philippos Edimiris, Laura Koch, Antje Enekwe, Claudia Lamina, Sabine Kasimir-Bauer, Rainer Kimmig and Hans Dieplinger

, and testosterone (ADVIA Centaur, Siemens Healthcare Diagnostics, Eschborn, Germany), androstenedione and sex hormone-binding globulin (SHBG) (Immulite 2000 XPi, Siemens Healthcare Diagnostics), and insulin (Immulite 2000 XPi, Siemens Healthcare

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Morten Ruge, Tea Skaaby, Anna-Maria Andersson and Allan Linneberg

hypothesized that an increased number of hours of sleep per night would lead to higher concentrations of serum testosterone, and thus, the present study sought to evaluate associations of sex hormone-binding globulin (SHBG), dihydroepiandrosteron-sulfate (DHEAS

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Ulla Schmidt, Birte Nygaard, Ebbe Winther Jensen, Jan Kvetny, Anne Jarløv and Jens Faber

known to be sensitive to changes in thyroid function, were studied (10, 11, 12, 13) . The markers include sex hormone-binding globulin (SHBG) representing liver function, N-terminal pro-brain natriuretic peptide (NT-proBNP) representing cardiac function