Filter

Refine by collections

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 1 - 10 of 53 items for :

Clear All
Emmi Naskali Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland

Search for other papers by Emmi Naskali in
Google Scholar
PubMed Close
,
Katja Dettmer Institute of Functional Genomics, University of Regensburg, Regensburg, Germany

Search for other papers by Katja Dettmer in
Google Scholar
PubMed Close
,
Peter J Oefner Institute of Functional Genomics, University of Regensburg, Regensburg, Germany

Search for other papers by Peter J Oefner in
Google Scholar
PubMed Close
,
Pedro A B Pereira Institute of Biotechnology, DNA Sequencing and Genomics Laboratory, University of Helsinki, Helsinki, Finland

Search for other papers by Pedro A B Pereira in
Google Scholar
PubMed Close
,
Kai Krohn Clinical Research Institute HUCH Ltd, Biomedicum Helsinki 1, Helsinki, Finland

Search for other papers by Kai Krohn in
Google Scholar
PubMed Close
,
Petri Auvinen Institute of Biotechnology, DNA Sequencing and Genomics Laboratory, University of Helsinki, Helsinki, Finland

Search for other papers by Petri Auvinen in
Google Scholar
PubMed Close
,
Annamari Ranki Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland

Search for other papers by Annamari Ranki in
Google Scholar
PubMed Close
, and
Nicolas Kluger Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland

Search for other papers by Nicolas Kluger in
Google Scholar
PubMed Close

of the gastrointestinal (GI) tract ( 9 , 10 ). Serotonin (5-hydroxytryptamine, 5-HT) is synthesized mainly (95%) by GI EE cells and in smaller amounts in the central nervous system ( 11 ). Its synthesis is derived from tryptophan (Trp) in a two

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0513
Volume/Issue:
Volume 8: Issue 1
Open access
Anela Blažević Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands

Search for other papers by Anela Blažević in
Google Scholar
PubMed Close
,
Anand M Iyer Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands

Search for other papers by Anand M Iyer in
Google Scholar
PubMed Close
,
Marie-Louise F van Velthuysen Department of Pathology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands

Search for other papers by Marie-Louise F van Velthuysen in
Google Scholar
PubMed Close
,
Johannes Hofland Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands

Search for other papers by Johannes Hofland in
Google Scholar
PubMed Close
,
Peter M van Koestveld Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands

Search for other papers by Peter M van Koestveld in
Google Scholar
PubMed Close
,
Gaston J H Franssen Department of Surgery, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands

Search for other papers by Gaston J H Franssen in
Google Scholar
PubMed Close
,
Richard A Feelders Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands

Search for other papers by Richard A Feelders in
Google Scholar
PubMed Close
,
Marina Zajec Laboratory of Neuro-Oncology/Clinical & Cancer Proteomics, Department of Neurology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands

Search for other papers by Marina Zajec in
Google Scholar
PubMed Close
,
Theo M Luider Laboratory of Neuro-Oncology/Clinical & Cancer Proteomics, Department of Neurology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands

Search for other papers by Theo M Luider in
Google Scholar
PubMed Close
,
Wouter W de Herder Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands

Search for other papers by Wouter W de Herder in
Google Scholar
PubMed Close
, and
Leo J Hofland Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, Netherlands

Search for other papers by Leo J Hofland in
Google Scholar
PubMed Close

well established that SI-NETs secrete a wide array of bioactive molecules, with a central role for the bioamine serotonin ( 2 , 3 ). Serotonin signaling is involved in various biological processes. Importantly, it can promote fibrosis development in

Article Type:
Research Article
Collections:
Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-22-0020
Volume/Issue:
Volume 11: Issue 4
Open access
Kylie D Rock Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA

Search for other papers by Kylie D Rock in
Google Scholar
PubMed Close
,
Brian Horman Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA

Search for other papers by Brian Horman in
Google Scholar
PubMed Close
,
Allison L Phillips Nicholas School of the Environment, Duke University, Durham, North Carolina, USA

Search for other papers by Allison L Phillips in
Google Scholar
PubMed Close
,
Susan L McRitchie NIH Eastern Regional Comprehensive Metabolomics Res. Core, Univ. of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

Search for other papers by Susan L McRitchie in
Google Scholar
PubMed Close
,
Scott Watson NIH Eastern Regional Comprehensive Metabolomics Res. Core, Univ. of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

Search for other papers by Scott Watson in
Google Scholar
PubMed Close
,
Jocelin Deese-Spruill NIH Eastern Regional Comprehensive Metabolomics Res. Core, Univ. of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

Search for other papers by Jocelin Deese-Spruill in
Google Scholar
PubMed Close
,
Dereje Jima Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA
Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina, USA

Search for other papers by Dereje Jima in
Google Scholar
PubMed Close
,
Susan Sumner NIH Eastern Regional Comprehensive Metabolomics Res. Core, Univ. of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA

Search for other papers by Susan Sumner in
Google Scholar
PubMed Close
,
Heather M Stapleton Nicholas School of the Environment, Duke University, Durham, North Carolina, USA

Search for other papers by Heather M Stapleton in
Google Scholar
PubMed Close
, and
Heather B Patisaul Department of Biological Sciences, North Carolina State University, Raleigh, North Carolina, USA
Center for Human Health and the Environment, North Carolina State University, Raleigh, North Carolina, USA

Search for other papers by Heather B Patisaul in
Google Scholar
PubMed Close

proliferation and migration, myelination and differentiation ( 86 , 87 ). That placental norepinephrine levels were reduced in low-dose females is also of interest given that gestational exposure to serotonin-norepinephrine reuptake inhibitors (SNRIs) can

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0373
Volume/Issue:
Volume 7: Issue 2
Open access
Jean-Benoît Corcuff Department of Nuclear Medicine, Haut Lévêque Hospital, Pessac, France
Nutrition et Neurobiologie intégrée, UMR 1286, University of Bordeaux, Bordeaux, France
Groupe de Biologie Spécialisée, Société Française de Médecine Nucléaire, Paris, France

Search for other papers by Jean-Benoît Corcuff in
Google Scholar
PubMed Close
,
Laurence Chardon Department of Biochemistry, Edouard Herriot Hospital, Lyon, France

Search for other papers by Laurence Chardon in
Google Scholar
PubMed Close
,
Ines El Hajji Ridah Biomnis, Lyon, France

Search for other papers by Ines El Hajji Ridah in
Google Scholar
PubMed Close
, and
Julie Brossaud Department of Nuclear Medicine, Haut Lévêque Hospital, Pessac, France
Nutrition et Neurobiologie intégrée, UMR 1286, University of Bordeaux, Bordeaux, France
Groupe de Biologie Spécialisée, Société Française de Médecine Nucléaire, Paris, France

Search for other papers by Julie Brossaud in
Google Scholar
PubMed Close

not discuss the level of diagnosis performed to quantify these analytes as this was covered in many publications. Urinary metabolite of serotonin, 5 hydroxy-indole acetic acid Because neuroendocrine cells may secrete serotonin, its main

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-17-0071
Volume/Issue:
Volume 6: Issue 6
Open access
Merete Gedde-Dahl
Search for other papers by Merete Gedde-Dahl in
Google Scholar
PubMed Close
,
Espen Thiis-Evensen
Search for other papers by Espen Thiis-Evensen in
Google Scholar
PubMed Close
,
Andreas Myklebust Tjølsen Section of Gastroenterology, University of Oslo School of Medicine, Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Postboks 4953, Nydalen, 0424 Oslo, Norway

Search for other papers by Andreas Myklebust Tjølsen in
Google Scholar
PubMed Close
,
Kjerstin Skrede Mordal
Search for other papers by Kjerstin Skrede Mordal in
Google Scholar
PubMed Close
,
Morten Vatn
Search for other papers by Morten Vatn in
Google Scholar
PubMed Close
, and
Deidi S Bergestuen
Search for other papers by Deidi S Bergestuen in
Google Scholar
PubMed Close

exclusively seen in patients with liver metastases, or metastases outside the abdominal cavity, as serotonin and other secretory products from the primary tumor are metabolized in the liver at first pass. Reportedly, 10–18% of patients with small intestinal

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-12-0077
Volume/Issue:
Volume 2: Issue 1
Open access
Irasema Mendieta Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico

Search for other papers by Irasema Mendieta in
Google Scholar
PubMed Close
,
Rosa Elvira Nuñez-Anita Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás Hidalgo, Morelia, Michoacán, Mexico

Search for other papers by Rosa Elvira Nuñez-Anita in
Google Scholar
PubMed Close
,
Gilberto Pérez-Sánchez Departmento de Psicoimunología, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, Mexico

Search for other papers by Gilberto Pérez-Sánchez in
Google Scholar
PubMed Close
,
Lenin Pavón Departmento de Psicoimunología, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Ciudad de México, Mexico

Search for other papers by Lenin Pavón in
Google Scholar
PubMed Close
,
Alfredo Rodríguez-Cruz Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico

Search for other papers by Alfredo Rodríguez-Cruz in
Google Scholar
PubMed Close
,
Guadalupe García-Alcocer Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico

Search for other papers by Guadalupe García-Alcocer in
Google Scholar
PubMed Close
, and
Laura Cristina Berumen Facultad de Química, Universidad Autónoma de Querétaro, Querétaro, Mexico

Search for other papers by Laura Cristina Berumen in
Google Scholar
PubMed Close

-methylxanthine (I7018), forskolin (F6886) and serotonin (H9523) were purchased from Sigma-Aldrich. All other chemicals were of the highest grade of purity commercially available. Cell culture A549/GFP cells and co-cultures were maintained in DMEM, and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0145
Volume/Issue:
Volume 7: Issue 5
Open access
Kjell Oberg Uppsala University, Uppsala, Sweden

Search for other papers by Kjell Oberg in
Google Scholar
PubMed Close
,
Eric Krenning Erasmus Medical Center, Rotterdam, Netherlands

Search for other papers by Eric Krenning in
Google Scholar
PubMed Close
,
Anders Sundin Uppsala University, Uppsala, Sweden

Search for other papers by Anders Sundin in
Google Scholar
PubMed Close
,
Lisa Bodei Memorial Sloan Kettering Cancer Center, New York, New York, USA

Search for other papers by Lisa Bodei in
Google Scholar
PubMed Close
,
Mark Kidd Wren Laboratories, Branford, Connecticut, USA

Search for other papers by Mark Kidd in
Google Scholar
PubMed Close
,
Margot Tesselaar Netherlands Cancer Institute, Amsterdam, Netherlands

Search for other papers by Margot Tesselaar in
Google Scholar
PubMed Close
,
Valentina Ambrosini University of Bologna, Bologna, Italy

Search for other papers by Valentina Ambrosini in
Google Scholar
PubMed Close
,
Richard P Baum Zentralklinik Bad Berka, Bad Berka, Germany

Search for other papers by Richard P Baum in
Google Scholar
PubMed Close
,
Matthew Kulke Dana Farber Cancer Institute, Boston, Massachusetts, USA

Search for other papers by Matthew Kulke in
Google Scholar
PubMed Close
,
Marianne Pavel Charite Hospital, Berlin, Germany

Search for other papers by Marianne Pavel in
Google Scholar
PubMed Close
,
Jaroslaw Cwikla University of Warmia and Mazury, Olsztyn, Poland

Search for other papers by Jaroslaw Cwikla in
Google Scholar
PubMed Close
,
Ignat Drozdov Wren Laboratories, Branford, Connecticut, USA

Search for other papers by Ignat Drozdov in
Google Scholar
PubMed Close
,
Massimo Falconi Ospedale San Raffaele, Milan, Italy

Search for other papers by Massimo Falconi in
Google Scholar
PubMed Close
,
Nicola Fazio IEO (European Institute of Oncology), Milan, Italy

Search for other papers by Nicola Fazio in
Google Scholar
PubMed Close
,
Andrea Frilling Imperial College London, London, UK

Search for other papers by Andrea Frilling in
Google Scholar
PubMed Close
,
Robert Jensen National Institutes of Health, Bethesda, Maryland, USA

Search for other papers by Robert Jensen in
Google Scholar
PubMed Close
,
Klaus Koopmans Martini Ziekenhuis, Groningen, Netherlands

Search for other papers by Klaus Koopmans in
Google Scholar
PubMed Close
,
Tiny Korse Netherlands Cancer Institute, Amsterdam, Netherlands

Search for other papers by Tiny Korse in
Google Scholar
PubMed Close
,
Dik Kwekkeboom Erasmus Medical Center, Rotterdam, Netherlands

Search for other papers by Dik Kwekkeboom in
Google Scholar
PubMed Close
,
Helmut Maecke University Hospital Freiburg, Freiburg, Germany

Search for other papers by Helmut Maecke in
Google Scholar
PubMed Close
,
Giovanni Paganelli Instituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Italy

Search for other papers by Giovanni Paganelli in
Google Scholar
PubMed Close
,
Ramon Salazar Instituto Catala d’Oncologia, Barcelona, Spain

Search for other papers by Ramon Salazar in
Google Scholar
PubMed Close
,
Stefano Severi Instituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Italy

Search for other papers by Stefano Severi in
Google Scholar
PubMed Close
,
Jonathan Strosberg H. Lee Moffitt Cancer Center, Tampa, Florida, USA

Search for other papers by Jonathan Strosberg in
Google Scholar
PubMed Close
,
Vikas Prasad Charite Hospital, Berlin, Germany

Search for other papers by Vikas Prasad in
Google Scholar
PubMed Close
,
Aldo Scarpa University of Verona, Verona, Italy

Search for other papers by Aldo Scarpa in
Google Scholar
PubMed Close
,
Ashley Grossman Univeristy of Oxford, Oxford, UK

Search for other papers by Ashley Grossman in
Google Scholar
PubMed Close
,
Annemeik Walenkamp University of Groningen, Groningen, Netherlands

Search for other papers by Annemeik Walenkamp in
Google Scholar
PubMed Close
,
Mauro Cives H. Lee Moffitt Cancer Center, Tampa, Florida, USA

Search for other papers by Mauro Cives in
Google Scholar
PubMed Close
,
Irene Virgolini Medical University Innsbruck, Innsbruck, Austria

Search for other papers by Irene Virgolini in
Google Scholar
PubMed Close
,
Andreas Kjaer Copenhagen University, Copenhagen, Denmark

Search for other papers by Andreas Kjaer in
Google Scholar
PubMed Close
, and
Irvin M Modlin Yale University, New Haven, Connecticut, USA

Search for other papers by Irvin M Modlin in
Google Scholar
PubMed Close

(5-HIAA; in serotonin-secreting tumors) have been used in this capacity ( 29 ). Secretory (monoanalyte) biomarkers for specific tumor types (insulinoma: insulin, gastrinoma: gastrin, glucagonoma: glucagon and VIPoma: VIP) are effective serum

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-16-0043
Volume/Issue:
Volume 5: Issue 5
Open access
Matilde Calanchini Oxford Centre for Diabetes, Endocrinology & Metabolism, Churchill Hospital, University of Oxford, Oxford, UK
Endocrinology & Metabolism Unit, CTO A. Alesini Hospital ASL Roma 2, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy

Search for other papers by Matilde Calanchini in
Google Scholar
PubMed Close
,
Michael Tadman Oxford Centre for Diabetes, Endocrinology & Metabolism, Churchill Hospital, University of Oxford, Oxford, UK

Search for other papers by Michael Tadman in
Google Scholar
PubMed Close
,
Jesper Krogh Oxford Centre for Diabetes, Endocrinology & Metabolism, Churchill Hospital, University of Oxford, Oxford, UK

Search for other papers by Jesper Krogh in
Google Scholar
PubMed Close
,
Andrea Fabbri Endocrinology & Metabolism Unit, CTO A. Alesini Hospital ASL Roma 2, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy

Search for other papers by Andrea Fabbri in
Google Scholar
PubMed Close
,
Ashley Grossman Oxford Centre for Diabetes, Endocrinology & Metabolism, Churchill Hospital, University of Oxford, Oxford, UK

Search for other papers by Ashley Grossman in
Google Scholar
PubMed Close
, and
Brian Shine Oxford Centre for Diabetes, Endocrinology & Metabolism, Churchill Hospital, University of Oxford, Oxford, UK

Search for other papers by Brian Shine in
Google Scholar
PubMed Close

mesenteric fibrosis ( 9 , 10 ). Serotonin is one of the most important biomarkers related to the development of CS, mesenteric fibrosis and carcinoid heart disease. Serotonin is produced in large amounts by NEN cells, most commonly in patients with NENs in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0269
Volume/Issue:
Volume 8: Issue 8
Open access
Paweł Komarnicki Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland

Search for other papers by Paweł Komarnicki in
Google Scholar
PubMed Close
,
Paweł Gut Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland

Search for other papers by Paweł Gut in
Google Scholar
PubMed Close
,
Jan Musiałkiewicz Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland

Search for other papers by Jan Musiałkiewicz in
Google Scholar
PubMed Close
,
Maja Cieślewicz Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland

Search for other papers by Maja Cieślewicz in
Google Scholar
PubMed Close
,
Adam Maciejewski Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland

Search for other papers by Adam Maciejewski in
Google Scholar
PubMed Close
,
Prachi Patel Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland

Search for other papers by Prachi Patel in
Google Scholar
PubMed Close
,
George Mastorakos Unit of Endocrinology, Diabetes Mellitus and Metabolism, Aretaieion University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece

Search for other papers by George Mastorakos in
Google Scholar
PubMed Close
, and
Marek Ruchała Department of Endocrinology, Metabolism and Internal Diseases, Poznan University of Medical Sciences, Poznań, Poland

Search for other papers by Marek Ruchała in
Google Scholar
PubMed Close

). Carcinoid syndrome (CS) is characterized by increased secretion of serotonin, and other biogenic amines and peptides. It manifests as a set of symptoms including diarrhea, skin flushing, and abdominal pain ( 15 ). Patients with liver metastases frequently

Article Type:
Research Article
Collections:
Cardiovascular
DOI:
https://doi.org/10.1530/EC-23-0249
Volume/Issue:
Volume 12: Issue 10
Open access
Dorte Glintborg Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

Search for other papers by Dorte Glintborg in
Google Scholar
PubMed Close
,
Magda Lambaa Altinok Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

Search for other papers by Magda Lambaa Altinok in
Google Scholar
PubMed Close
,
Pernille Ravn Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark

Search for other papers by Pernille Ravn in
Google Scholar
PubMed Close
,
Kurt Bjerregaard Stage Department of Psychiatry, Odense University Hospital, Odense, Denmark

Search for other papers by Kurt Bjerregaard Stage in
Google Scholar
PubMed Close
,
Kurt Højlund Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

Search for other papers by Kurt Højlund in
Google Scholar
PubMed Close
, and
Marianne Andersen Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

Search for other papers by Marianne Andersen in
Google Scholar
PubMed Close

in PCOS could be associated with increased HPA activity ( 11 ). Treatment with specific serotonin reuptake inhibitor (SSRI) is the first choice for depression and 16.3% Danish women with PCOS had prescriptions of antidepressants ( 6 ). The possible

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0077
Volume/Issue:
Volume 7: Issue 3
Open access