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observational studies. Materials and methods Study design and ethics The NordiNet® International Outcomes Study (IOS; NCT00960128) and ANSWER Program (NCT01009905) were observational, multicentre studies monitoring the real-world long-term outcomes
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Cambridge University Hospitals NHS Foundation Trust, Wolfson Diabetes and Endocrine Clinic, Cambridge, UK
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Shin J & Cohen O . Comparison of MiniMed 780G system performance in users aged younger and older than 15 years: evidence from 12 870 real-world users . Diabetes, Obesity and Metabolism 2022 24 1370 – 1379 . ( https://doi.org/10.1111/dom.14714
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+ ( 46 ). Real world practice An analysis from a primary care database in the UK showed that TSH was higher than the first-trimester guideline goal of 2.5 μIU/mL for 46% of 1,013 pregnancies in women who had been taking LT4 for at least 6 months
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Xiamen Key Laboratory for Clinical Efficacy and Evidence-Based Research of Traditional Chinese Medicine, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China
Fujian Province Key Laboratory of Diabetes Translational Medicine, The First Affiliated Hospital of Xiamen University, School of medicine, Xiamen University, Xiamen, China
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Database (SHLD) to provide new real-world evidence for the management and therapy of T2DM. Methods Data source Data in this study were extracted from SHLD, which included electronic health records (EHRs) for patients from 37 tertiary hospitals
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paediatric population, the fact remains that the adverse effects of therapy with levothyroxine in this special population are not known ( 28 , 29 ). In this scenario, it becomes essential to provide real-world evidence on SH in paediatric population
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. The study further highlights the issue beyond previously published data from real-world evidence on the oncology safety of GLP-1RAs ( 41 ). However, data should be read cautiously ( 42 ). First, the risk and benefits should always be addressed and
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use CGM. The first hospitals in the US to start using CGM were in New York City, where the pandemic was hitting the hardest. Soon after, other institutions started using CGM, implementing new protocols, and analyzing their real-world evidence (RWE
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Primer sequences for real-time RT-PCR. Primers Sequence (5′→3′) Pdx-1 promoter Forward: GGTACCGGTACCTCCAGTATCAGG Reverse: CTCGAGGAGCTACAAGCCAGGCCT Pdx-1 real-time PCR Forward: TAGGCGTCGCACAAGAAGAA Reverse
Department of Oncology and Metabolism, The Medical School, The University of Sheffield, Sheffield, UK
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Department of Oncology and Metabolism, The Medical School, The University of Sheffield, Sheffield, UK
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efficacy of the ESE guidelines in a ‘real-world’ setting. Materials and methods We conducted a retrospective, observational, cohort study that examined the use of HTS for severe symptomatic hyponatraemia at Sheffield Teaching Hospitals (Northern
Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Shanghai National Clinical Research Center for Metabolic Diseases, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission of the PR China, Shanghai Key Laboratory for Endocrine Tumor, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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of insulin therapy with the risk of three subtypes of BTC using real-world data. Materials and methods Database The data used in this study were obtained from the Shanghai Hospital Link Database (SHLD). SHLD is a part of the Shanghai