Search Results

You are looking at 1 - 10 of 214 items for :

  • proliferation x
Clear All
Open access

Qi Che, Xirong Xiao, Jun Xu, Miao Liu, Yongning Lu, Suying Liu and Xi Dong

mechanism of cancer proliferation and invasion bio-behavior will be of great significance for the clinical treatment of malignant tumor patients. As one of the most important hormone-dependent cancers, the tumorigenesis and progression of endometrial

Open access

Amarjit Saini, Linda Björkhem-Bergman, Johan Boström, Mats Lilja, Michael Melin, Karl Olsson, Lena Ekström, Peter Bergman, Mikael Altun, Eric Rullman and Thomas Gustafsson

on myoblast proliferation and differentiation suggesting it is important in maintaining the SC pool ( 16 ). The VDR gene has multiple polymorphisms, most of which are identified by a bi-allelic variation in the restriction endonuclease site (e

Open access

Corina Verónica Sasso, Flavia Eliana Santiano, Fiorella Campo Verde Arboccó, Leila Ester Zyla, Silvana Noemí Semino, Martin Eduardo Guerrero-Gimenez, Virginia Pistone Creydt, Constanza Matilde López Fontana and Rubén Walter Carón

models showed a lower risk of CRC in the presence of estrogens ( 3 , 4 ). Nevertheless, some studies indicate that, once the disease has developed, estrogens inhibit cell proliferation, while others suggest they induce mitogenic effects ( 5 ). The

Open access

Jintao Hu, Qingbo Chen, Xiao Ding, Xin Zheng, Xuefeng Tang, Song Li and Hui Yang

proliferation assay We used the WST-8 Cell Counting Kit-8 (CCK-8, Dojindo Laboratories, Mashiki-machi, Kumamoto, Japan) to measure cell proliferation based on the manufacturer’s instructions. The doubling time (DT) was obtained using the exponential growth

Open access

Xuechao Jiang, Yonghui Wang, Xiaoying Li, Leqi He, Qian Yang, Wei Wang, Jun Liu and Bingbing Zha

focused on lncRNA–mRNA pairs that were abnormally regulated in GD, especially those involving protein-coding genes that were related to cell proliferation. Among the identified genes, TCL1 family AKT coactivator A ( TCL1A ), and SH2 domain containing 1A

Open access

R C S van Adrichem, L J Hofland, R A Feelders, M C De Martino, P M van Koetsveld, C H J van Eijck, R R de Krijger, D M Sprij-Mooij, J A M J L Janssen and W W de Herder

Introduction Gastroenteropancreatic neuroendocrine tumors (GEP NETs) are rare and heterogeneous tumors which may vary according to their biological, functional, and clinical behavior (1) . Chromogranin A (CgA) and the Ki-67 proliferation index are

Open access

María J Gómora, Flavia Morales-Vásquez, Enrique Pedernera, Delia Perez-Montiel, Horacio López-Basave, Antonio R Villa, Azucena Hernández-Martínez, Esteban Mena and Carmen Mendez

that can increase the incidence as well as tumor aggressiveness ( 8 , 9 , 10 ). Sexual steroid hormones acting through their receptors regulate signaling pathways related to cell proliferation, epithelial–mesenchymal transition, apoptosis, cell

Open access

Irasema Mendieta, Rosa Elvira Nuñez-Anita, Gilberto Pérez-Sánchez, Lenin Pavón, Alfredo Rodríguez-Cruz, Guadalupe García-Alcocer and Laura Cristina Berumen

-resistant tumours and metastasis ( 3 , 4 ). The main characteristics of tumours with a neuroendocrine phenotype are low proliferation rates, polygonal morphology, dense chromatin and a specific distribution pattern, that is nests, trabecular, acinar and rosette

Open access

K E Lines, R P Vas Nunes, M Frost, C J Yates, M Stevenson and R V Thakker

in vivo studies several MEN1 mouse models have been generated and investigations of these have yielded important insights in NET cell proliferation and responses to treatments. For example, conventional heterozygous germline Men1 -knockout mouse

Open access

Wei Li, Qing Huang, Danyang Sun, Guizhi Zhang and Jian Tan

and proliferation. Materials and methods Patient clinical data Before this study began, written informed consent was obtained from all patients who participated in the study, which was approved by the Ethics Committee of Tianjin Medical