should also consider progesterone (P4) as another of the ovarian steroids involved in this disease. There are some studies reporting the absence of the expression of progesterone receptor (PR) in colon tumors and no effect of progestins on carcinogenesis
Estradiol and progesterone regulate proliferation and apoptosis in colon cancer
Corina Verónica Sasso, Flavia Eliana Santiano, Fiorella Campo Verde Arboccó, Leila Ester Zyla, Silvana Noemí Semino, Martin Eduardo Guerrero-Gimenez, Virginia Pistone Creydt, Constanza Matilde López Fontana, and Rubén Walter Carón
Effects of low-dose oral micronised progesterone on sleep, psychological distress, and breast development in transgender individuals undergoing feminising hormone therapy: a prospective controlled study
Brendan J Nolan, Aviva S Frydman, Shalem Y Leemaqz, Meg Carroll, Mathis Grossmann, Jeffrey D Zajac, and Ada S Cheung
development of physical characteristics that align with their gender identity and improves mental health ( 1 ). There has been an ongoing debate regarding the inclusion of progesterone in feminising hormone therapy regimens. Some suggest progesterone may aid
EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner
A Rehfeld, D L Egeberg, K Almstrup, J H Petersen, S Dissing, and N E Skakkebæk
-mediated Ca 2+ influx ( 9 ). CatSper is activated by the natural ligands progesterone and prostaglandins ( 10 , 11 ), which lead to a rapid Ca 2+ influx into the sperm cell. The cumulus cells surrounding the egg release progesterone and the progesterone
Hormone receptor expression of colorectal cancer diagnosed during the peri-partum period
Jordyn Silverstein, Wesley Kidder, Susan Fisher, Thomas A Hope, Samantha Maisel, Dianna Ng, Jessica Van Ziffle, Chloe E Atreya, and Katherine Van Loon
studies have sought to evaluate the expression of estrogen receptors (ERs) and progesterone receptors (PRs) in colorectal tumor cells, results have been mixed. Earlier studies reported that 20–90% of CRC tumors express ER and PR ( 19 , 20 , 21 ); however
Risk of primary brain tumour after breast cancer
Anne M Drewes, Maria E Møller, Rasmus Hertzum-Larsen, Gerda Engholm, and Hans H Storm
increased risk of brain tumour in premenopausal women with breast cancer and a protective effect in postmenopausal women, hormonal levels (oestrogen and progesterone) could possibly have a role in the risk for developing a second primary brain tumour
Elevated free fatty acids affect bovine granulosa cell function: a molecular cue for compromised reproduction during negative energy balance
Arpna Sharma, Vijay Simha Baddela, Frank Becker, Dirk Dannenberger, Torsten Viergutz, and Jens Vanselow
the test groups with highest fatty acid concentrations. Steroid hormone estimation Concentrations of 17β-estradiol (E2) and progesterone (P4) in the conditioned media were determined by competitive 3H radioimmunoassay (RIA) with rabbit
Bridging progestogens in pregnancy and pregnancy prevention
Elizabeth Micks, Greta B Raglan, and Jay Schulkin
Introduction Progesterone, progestins, and progestogens Progesterone is a C-21 steroid hormone first identified and characterized by Willard Myron Allen in 1933. C-21 steroid hormones contain 21 carbons and are also referred to as pregnanes. This
The levels of adipokines in relation to hormonal changes during the menstrual cycle in young, normal-weight women
Katarzyna Wyskida, Grzegorz Franik, Tomasz Wikarek, Aleksander Owczarek, Alham Delroba, Jerzy Chudek, Jerzy Sikora, and Magdalena Olszanecka-Glinianowicz
the menstrual cycle in both ovulatory and anovulatory women. Additionally, in some ( 13 ), but not in other studies ( 14 ), the association between changes in plasma leptin levels and variations of both estradiol and progesterone release were observed
Cyclic changes in cortisol across the estrous cycle in parous and nulliparous Asian elephants
Kerry V Fanson, Tamara Keeley, and Benjamin G Fanson
( Elephas maximus ). In concert with progesterone data, we present an extensive examination of cortisol patterns across the estrous cycle in both parous and nulliparous females ( Table 1 ). First, we characterized the broad patterns of cortisol expression
Interrelationships among reproductive hormones and antral follicle count in human menstrual cycles
David Mark Robertson, Chel Hee Lee, and Angela Baerwald
). The key ovarian factors believed responsible are the steroids, oestradiol and progesterone, and the protein hormones, inhibin A and B. However, their respective roles are not clearly understood. In a previous study (( 2 ), and ( 3 ) designated in
