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Diagnosis of hypothyroidism during pregnancy Evolution of normal thyroid function during pregnancy Circulating levels of human chorionic gonadotrophin (hCG) increase from about 11 days post conception, reach a peak around the end of the
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of adrenal crisis ( 2 ), and premature mortality ( 13 , 14 ). In patients of reproductive age, AI may have consequences on fertility, reproduction, and pregnancy outcomes ( 15 , 16 ). Patients with AI on optimal GC replacement pre-conception are
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Introduction Maternal obesity and excessive weight gain during pregnancy is a condition that increases the risk of several complications for both the mother and the growing fetus, with a risk that the fetus will suffer from a suboptimal
Adelaide Medical School, The University of Adelaide, Adelaide, Australia
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Adelaide Medical School, The University of Adelaide, Adelaide, Australia
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Introduction Successful pregnancy requires major physiological adaptations in the mother to support pregnancy, and the attachment, implantation, growth and function of the placental interface between mother and foetus ( 1 ). Growth hormone (GH
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hyperglycemia in nondiabetic women ( 3 , 4 ). Concordantly, experiments with rats showed that exposure to dexamethasone (DEX) during the last third of pregnancy impaired maternal glucose-induced insulin secretion in vivo , leading to glucose intolerance prior
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Department of Gynecology and Obstetrics, Copenhagen University Hospital (Hvidovre Hospital), Hvidovre, Denmark
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Carelink Nærhospital, Roskilde, Denmark
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Institute of Clinical Medicine, Faculty of Health and Clinical Research, Copenhagen University, Copenhagen, Denmark
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Université Libre de Bruxelles (ULB), Brussels, Belgium
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, depending on the iodine intake in the investigated area and the ethnic background ( 1 , 2 , 3 , 4 , 5 , 6 ). TAI is the strongest predictor for the development of subclinical or overt thyroid dysfunction in the preconception, during pregnancy, and in
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Introduction There is a high prevalence of 25-hydroxyvitamin D (25OHD) deficiency during pregnancy ( 1 ). In the United States, a prevalence of 33% has been reported, while in countries such as Turkey, the prevalence reaches 90% ( 1 ). 25OHD
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark
Steno Diabetes Center North Jutland, Aalborg University Hospital, Aalborg, Denmark
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Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark
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Introduction Maternal thyroid function in early pregnancy is a debated matter ( 1 , 2 ). The role of thyroid hormones in fetal brain development has long drawn ample attention to the potential adverse consequences of abnormal maternal thyroid
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Introduction Pregnancy is a unique period of female life when a series of hormone changes jointly regulate thyroid function. Maternal human chorionic gonadotropin (hCG) levels peak at 30,000–100,000 U/L in the eighth to tenth week of gestation
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
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Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark
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predominantly occurs in female patients and in the reproductive time span, the management of the disease should consider the patient’s reproductive history and the possibility of a current or future pregnancy ( 1 , 2 ). GD is an autoimmune disease caused by