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EFS, colonic neuromuscular relaxation distinctly increased in the HGD and HFD groups ( Fig. 4A and B , P < 0.01). Meanwhile, EFS-stimulated colonic neuromuscular relaxation was significantly decreased after pre-incubation with l -NAME in the NFD
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Division of Haematology-Oncology and Stem Cell Transplantation, Children’s Hospital, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Edinburgh Royal Hospital for Sick Children, Edinburgh, UK
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important for regulating factors (e.g. retinoic acid) that prevent premature meiotic development in germ cells of the foetal testis, thus supporting the development of pre-spermatogonia ( 28 , 29 ). In mice, this includes effects on the retinoic acid
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University Hospital, Krakow, Poland
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response as they can express and produce anti-inflammatory cytokines (IL-1a, TGF-B), colony-stimulating factors (G-CSF, GM-CSF) and immunomodulatory cytokines ( 28 ). It was also shown that defensin human neutrophil peptide-1 (HNP-1) is able to inhibit
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humans. More studies are needed to clarify the relationship between vaspin and thyroid hormones. Visfatin Visfatin, previously defined as pre-B cell colony-enhancing factor, is a 52-kDa cytokine expressed and secreted by lymphocytes (57) . Visfatin is
The Center for Biomedical Research, Tongji Hospital Research Building, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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cells. Subsequent studies, however, indicated that SGK1 is widely expressed in various cell types following a vast array of external stimulations, such as transforming growth factor-β (TGF-β) and interleukin 6 (IL-6) ( 4 ). Multiple endocrine hormones
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Institute of Oncology, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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Pathology 2002 161 195 – 206 . ( https://doi.org/10.1016/S0002-9440(10)64171-5 ) 10.1016/S0002-9440(10)64171-5 24 Chen MP Chung FM Chang DM Tsai JC Huang HF Shin SJ Lee YJ . Elevated plasma level of visfatin/pre-B cell colony-enhancing
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Institute of Pathology, Institute of Pathology Nordhessen, Institute of Transfusion Medicine and Immunology, Departments of Urology and Pediatric Urology, University Medical Center Mannheim, Institute of Pathology, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1–3, 68135 Mannheim, Germany
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Institute of Pathology, Institute of Pathology Nordhessen, Institute of Transfusion Medicine and Immunology, Departments of Urology and Pediatric Urology, University Medical Center Mannheim, Institute of Pathology, University Medical Center Mannheim, University of Heidelberg, Theodor-Kutzer-Ufer 1–3, 68135 Mannheim, Germany
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enhancer. IGFs regulate cell growth and differentiation in humans. IGF2 is the predominant IGF in adults (17) and is imprinted in most tissues with few exceptions such as choroid plexus, leptomeninges, developing retina, and thymus (18, 19) . LOI and
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
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FM Chang DM Tsai JC Huang HF Shin SJ Lee YJ . Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus . Journal of Clinical Endocrinology and Metabolism 2006 91 295 – 299 . ( https
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offspring ( 1 , 3 ). The pathogenesis of GDM is still unclear, but there is growing evidence that genetic variants, advanced maternal age, pre-pregnancy BMI, oxidative stress, chronic inflammation, dyslipidemia, unbalanced hormone secretion, and/or β-cell
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octreotide caused no enhanced anti-tumour activity in comparison to mTORC1 inhibition alone in human NET cell lines BON1 and H727 ( 66 , 68 , 86 ) and primary tumour cells in vitro . The lack of effect of octreotide in BON1 and H727 cells might be because