Centre de Référence des Maladies Rares du Calcium et du Phosphore Filière de Santé Maladies Rares OSCAR, Paris, France
Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, INSERM, UMRS1138, Paris, France
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Université Paris-Saclay, Inserm U1185, Physiologie et Physiopathologie Endocriniennes, Assistance Publique-Hôpitaux de Paris, Service d’Endocrinologie et Diabète de l’Enfant, Centre de Référence des Maladies Rares du Calcium et du Phosphore et Filière de Santé Maladies Rares OSCAR, Hôpital Bicêtre Paris Saclay, Le Kremlin-Bicêtre, France
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Centre de Référence des Maladies Rares du Calcium et du Phosphore Filière de Santé Maladies Rares OSCAR, Paris, France
Assistance Publique-Hôpitaux de Paris, Institut Necker-Enfants Malades, INSERM U1151 – CNRS UMR 8253, Paris, France
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Association Francophone de Chirurgie Endocrinienne (AFCE), France
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Assistance Publique-Hôpitaux de Paris, Hôpital Cochin, Biochimie et Génétique Moléculaires, Paris, France
INSERM, U1169, Université Paris Sud, Hôpital Bicêtre, Le Kremlin Bicêtre, France
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INSERM, U1418, CIC-EC, Hôpital Européen Georges Pompidou, Paris, France
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Centre de Référence des Maladies Rares du Calcium et du Phosphore Filière de Santé Maladies Rares OSCAR, Paris, France
Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, Université de Paris, INSERM, UMRS1138, Paris, France
CNRS, ERL8228, Paris, France
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phenotypic variability of hypoparathyroidism, physicians involved in the care and follow-up of patients range from pediatricians to endocrinologists and work in very different settings and from family medicine offices to tertiary care hospitals. To increase
Diabetes and Endocrine Clinic, Mediclinic Airport Road Hospital, Abu Dhabi, United Arab Emirates
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sunset. To achieve good holistic management, harmony is needed between physicians and religious scholars ( 1 ). Fasting entails protracted periods of fasting, often exceeding 12-h per day. Prolonged abstinence, particularly in hot climates, subjects many
Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands
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Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands
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Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands
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Department of Rare Disorders and Disabilities, Oslo University Hospital, NevSom, Oslo, Norway
University of Oslo, Norwegian Centre for Mental Disorders Research (NORMENT) and KG Jebsen Centre for Neurodevelopmental Disorders, Oslo, Norway
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Introduction The patient–physician relationship is critical for patients’ health. For example, optimal trust and therapeutic alliance positively affect patients’ psychological well-being, adherence to medication, and treatment response ( 1
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. We distributed the two questionnaires on nonpregnancy and pregnancy issues during different topics on the live platform. All physicians could voluntarily participate in the surveys. Neither the forum organizer nor the authors directly contacted the
IRCCS, Istituto Auxologico Italiano, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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physicians. Methods Patient questionnaire design A 12-item patient questionnaire was developed based on the generally understood clinical characteristics and symptomology of CS, aiming to assess patients’ experiences of symptoms, diagnosis, care
Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands
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Università “Federico II” di Napoli, Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Naples, Italy
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Department of Endocrinology and Metabolism, Amsterdam Gastroenterology Endocrinology & Metabolism, Amsterdam University Medical Centre, University of Amsterdam, Amsterdam, Netherlands
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Adult Chair of MTG Pituitary of Endo-ERN
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from childhood to adulthood. Despite the importance of this period, agreement on how to define (timing of) transition is nonexistent. Previously, physicians have defined transition as the transitional phase between the end of puberty and reaching peak
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. Respondents were predominantly physicians, with less than 5% other HC professionals, 53% were female and 96% represented University hospitals. Of the respondents, 36% were pediatric, 59% adult specialists and 5% others. Most participants were >40 years (81
Department of Endocrinology, St James’s Hospital, Dublin, Ireland
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Department of Endocrinology, University of Manchester, Manchester, UK
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Department of Paediatric Endocrinology & Diabetes, Newcastle-upon-Tyne Hospitals, Newcastle upon Tyne, UK
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Endocrine Research Group, Institute of Genetic Medicine, University of Newcastle-upon-Tyne, Newcastle upon Tyne, UK
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Physician factors/errors Belief that ‘simple reassurance’ is the only required first-line management for case of absent puberty beyond age 14 Belief that partial puberty (testicular volume ≥4 mL) means that progression of puberty to completion is
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several drugs affect the dynamic test results. By describing and discussing a clinical case, this review attempts to answer some common questions that physicians may face in the clinical practice. Clinical case A 26-year-old female was referred
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First Pavlov State Medical University, St. Petersburg, Russia
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First Pavlov State Medical University, St. Petersburg, Russia
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Objective
The aim of our study was to investigate the distribution of the PHPT clinical manifestations and biochemical features in patients who underwent parathyroidectomy.
Materials and methods
Medical records of 449 patients from three Medical Centers (Saint-Petersburg, Russia), hospitalized during a period from 2011 to 2018, were reviewed. History and anthropometric data, laboratory results (iPTH, total and iCa, phosphorus, ALP, 24-h urinary calcium, 25(OH)D) and imaging data (ultrasonography, scintigraphy, CT/MRI scan, DXA) were analyzed.
Results
Three hundred ninety-four patients were included in the final analysis. Median age was 60 years with 94.2% being women. Symptomatic disease was evident in 222 (56.4%) patients, asymptomatic in 172 (43.6%). Skeletal involvement was more common for women, while frequency of other manifestations did not differ in both genders. There was no difference between symptomatic and asymptomatic patients in age. Serum iPTH level was higher in symptomatic patients (202.9 and 181.0 pg/mL, P = 0.022). Serum 25(OH)D level was estimated in few patients and negatively correlated with PTH (r = ¯0.294, P = 0.005), iCa (r = ¯0.268, P = 0.010) and total Ca (r = ¯0.284, P = 0.014) levels. Manifestations of CVD were observed in 67.7% of cases and affected equally both symptomatic and asymptomatic patients (70.7 and 63.4%, P = 0.076). Both age and BMI were higher in patients with CVD, whether or not they were symptomatic (62 and 53 years, P < 0.0001; 30.4 vs 26.0 kg/m2, P < 0.0001, respectively).
Conclusions
This experience illustrates that symptomatic phenotype is still the most common form of PHPT.