Hongyan Wang
Hongyan Wang
Department of Urology, Shengjing Hospital of China Medical University, Shenyang, China
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Bin Wu
Bin Wu
Department of Urology, Shengjing Hospital of China Medical University, Shenyang, China
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Zichuan Yao
Zichuan Yao
Department of Urology, Shengjing Hospital of China Medical University, Shenyang, China
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Xianqing Zhu
Xianqing Zhu
Department of Urology, Shengjing Hospital of China Medical University, Shenyang, China
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Yunzhong Jiang
Yunzhong Jiang
Department of Urology, Shengjing Hospital of China Medical University, Shenyang, China
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Song Bai
Song Bai
Department of Urology, Shengjing Hospital of China Medical University, Shenyang, China
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Introduction A pheochromocytoma is a rare neuro-endocrine tumor that arises from the chromaffin cells of the adrenal medulla with an incidence of 0.2–0.8 cases/100,000 persons/year, which present in 0.1–1% of patients with hypertension and
Raluca Maria Furnica
Raluca Maria Furnica
Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
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Muhammad Muddaththir Dusoruth
Muhammad Muddaththir Dusoruth
Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
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Alexandre Persu
Alexandre Persu
Department of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
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Damien Gruson
Damien Gruson
Department of Biology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
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Michel Mourad
Michel Mourad
Endocrine Surgery, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
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Dominique Maiter
Dominique Maiter
Department of Endocrinology and Nutrition, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium
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Introduction Clinical presentation of pheochromocytomas and paragangliomas (PPGL) is highly variable, making early diagnosis often challenging. The pattern and haemodynamic effects of tumoural catecholamine secretion may indeed vary from a
Randi Ugleholdt
Randi Ugleholdt
Department of Endocrinology, Copenhagen University Hospital Herlev and Gentofte, Herlev, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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Åse Krogh Rasmussen
Åse Krogh Rasmussen
Department of Endocrinology and Metabolism, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
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Pernille A H Haderslev
Pernille A H Haderslev
Department of Anaesthesiology, Copenhagen University Hospital Herlev and Gentofte, Herlev, Denmark
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Bjarne Kromann-Andersen
Bjarne Kromann-Andersen
Department of Urology, Copenhagen University Hospital Herlev and Gentofte, Herlev, Denmark
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Claus Larsen Feltoft
Claus Larsen Feltoft
Department of Endocrinology, Copenhagen University Hospital Herlev and Gentofte, Herlev, Denmark
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Introduction Surgery of pheochromocytoma and paraganglioma (PPGL) carries a risk of hemodynamic instability during induction of anesthesia and manipulation of the tumor ( 1 , 2 ). Previously, the mortality related to surgical resection was
Joakim Crona
Joakim Crona
Departments of Surgical Sciences, Medical Sciences, Uppsala University, S-751 85 Uppsala, Sweden
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Alberto Delgado Verdugo
Alberto Delgado Verdugo
Departments of Surgical Sciences, Medical Sciences, Uppsala University, S-751 85 Uppsala, Sweden
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Dan Granberg
Dan Granberg
Departments of Surgical Sciences, Medical Sciences, Uppsala University, S-751 85 Uppsala, Sweden
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Staffan Welin
Staffan Welin
Departments of Surgical Sciences, Medical Sciences, Uppsala University, S-751 85 Uppsala, Sweden
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Peter Stålberg
Peter Stålberg
Departments of Surgical Sciences, Medical Sciences, Uppsala University, S-751 85 Uppsala, Sweden
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Per Hellman
Per Hellman
Departments of Surgical Sciences, Medical Sciences, Uppsala University, S-751 85 Uppsala, Sweden
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Peyman Björklund
Peyman Björklund
Departments of Surgical Sciences, Medical Sciences, Uppsala University, S-751 85 Uppsala, Sweden
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Introduction Pheochromocytomas (PCCs) and paragangliomas (PGLs) are rare tumours arising from chromaffin cells in adrenal medulla and autonomous ganglia. A majority of these tumours have a low proliferation and seldom metastasize. The understanding
Henrik Falhammar
Henrik Falhammar
Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Stockholm, Sweden
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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Magnus Kjellman
Magnus Kjellman
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Department of Breast and Endocrine Surgery, Karolinska University Hospital, Stockholm, Sweden
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Department of Breast and Endocrine Surgery, Karolinska University Hospital, Stockholm, Sweden
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Jan Calissendorff
Jan Calissendorff
Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Stockholm, Sweden
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
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Introduction Pheochromocytomas are neuroendocrine tumors arising from chromaffin cells of the adrenal medulla or in extra-adrenal paraganglia producing catecholamines. Tumors outside the adrenals are usually called extra
Sanjeet Kumar Jaiswal
Sanjeet Kumar Jaiswal
Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Vijaya Sarathi
Vijaya Sarathi
Department of Endocrinology, Vydehi Institute of Medical Sciences and Research Center, Bengaluru, Karnataka, India
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Saba Samad Memon
Saba Samad Memon
Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Robin Garg
Robin Garg
Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Gaurav Malhotra
Gaurav Malhotra
Department of Nuclear Medicine, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India
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Priyanka Verma
Priyanka Verma
Department of Nuclear Medicine, Bhabha Atomic Research Centre, Mumbai, Maharashtra, India
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Ravikumar Shah
Ravikumar Shah
Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Manjeet Kaur Sehemby
Manjeet Kaur Sehemby
Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Virendra A Patil
Virendra A Patil
Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Swati Jadhav
Swati Jadhav
Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Anurag Ranjan Lila
Anurag Ranjan Lila
Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Nalini S Shah
Nalini S Shah
Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Tushar R Bandgar
Tushar R Bandgar
Department of Endocrinology, Seth G.S Medical College and KEM Hospital, Mumbai, Maharashtra, India
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Introduction Pheochromocytomas (PCC)–paragangliomas (PGL) (PPGL) are rare tumors of neural crest origin with malignant potential. The prevalence of metastasis ranges from 2–13% in PCC to 2.4–50% in PGL ( 1 , 2 ). In patients with unresectable
Jan Kvasnička
Jan Kvasnička
3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic
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Ondřej Petrák
Ondřej Petrák
3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic
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Tomáš Zelinka
Tomáš Zelinka
3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic
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Judita Klímová
Judita Klímová
3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic
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Barbora Kološová
Barbora Kološová
3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic
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Květoslav Novák
Květoslav Novák
Department of Urology, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic
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David Michalský
David Michalský
1st Department of Surgery, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic
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Jiří Widimský Jr
Jiří Widimský Jr
3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic
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Robert Holaj
Robert Holaj
3rd Department of Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Praha, Czech Republic
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Introduction Pheochromocytomas (PHEO) and functional paragangliomas (PGLs) are rare and mostly non-metastatic tumours originating from chromaffin tissue either from the adrenal medulla (PHEO) or from the vegetative nervous system
João Castro-Teles
João Castro-Teles
Department of Biomedicine, Faculty of Medicine of the University of Porto, Porto, Portugal
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Bernardo Sousa-Pinto
Bernardo Sousa-Pinto
MEDCIDS, Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal
CINTESIS, Center for Health Technology and Services Research, University of Porto, Porto, Portugal
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CINTESIS, Center for Health Technology and Services Research, University of Porto, Porto, Portugal
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Sandra Rebelo
Sandra Rebelo
Department of Biomedicine, Faculty of Medicine of the University of Porto, Porto, Portugal
Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal
Department of Clinical Pathology, Centro Hospitalar Universitário de São João (CHUSJ), Porto, Portugal
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Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal
Department of Clinical Pathology, Centro Hospitalar Universitário de São João (CHUSJ), Porto, Portugal
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Duarte Pignatelli
Duarte Pignatelli
Department of Biomedicine, Faculty of Medicine of the University of Porto, Porto, Portugal
Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Department of Endocrinology, Centro Hospitalar Universitário de São João (CHUSJ), Porto, Portugal
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Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal
Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
Department of Endocrinology, Centro Hospitalar Universitário de São João (CHUSJ), Porto, Portugal
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neoplasms, such as hemangioblastomas and pheochromocytomas. Pheochromocytomas and paragangliomas (PPGLs), arising either through germline VHL mutations in a syndromic setting or via somatic VHL mutations sporadically, associate with the pseudo
Natalie Rogowski-Lehmann
Natalie Rogowski-Lehmann
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany
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Aikaterini Geroula
Aikaterini Geroula
Institut für Klinische Chemie und Laboratoriumsmedizin, Universitätsklinikum Carl Gustav Carus an der TU Dresden, Dresden, Germany
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Aleksander Prejbisz
Aleksander Prejbisz
Department of Hypertension, Institute of Cardiology, Warsaw, Poland
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Henri J L M Timmers
Henri J L M Timmers
Section of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
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Felix Megerle
Felix Megerle
Medizinische Klinik und Poliklinik I des Universitätsklinikums Würzburg, Würzburg, Germany
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Mercedes Robledo
Mercedes Robledo
Hereditary Endocrine Cancer Group, Human Cancer Genetics Programme, Spanish National Cancer Research Centre, Centro de Investigacion Biomedica en Red de Enfermedades Raras (CIBERER), Madrid, Spain
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Martin Fassnacht
Martin Fassnacht
Medizinische Klinik und Poliklinik I des Universitätsklinikums Würzburg, Würzburg, Germany
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Stephanie M J Fliedner
Stephanie M J Fliedner
First Department of Medicine, University Medical Center Schleswig-Holstein, Lübeck, Germany
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Martin Reincke
Martin Reincke
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany
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Anthony Stell
Anthony Stell
Department of Computing and Information, University of Melbourne, Melbourne Australia
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Andrzej Januszewicz
Andrzej Januszewicz
Department of Hypertension, Institute of Cardiology, Warsaw, Poland
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Jacques W M Lenders
Jacques W M Lenders
Section of Endocrinology, Department of Internal Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands
Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus an der Technische Universität Dresden, Dresden, Germany
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Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus an der Technische Universität Dresden, Dresden, Germany
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Graeme Eisenhofer
Graeme Eisenhofer
Institut für Klinische Chemie und Laboratoriumsmedizin, Universitätsklinikum Carl Gustav Carus an der TU Dresden, Dresden, Germany
Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus an der Technische Universität Dresden, Dresden, Germany
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Medizinische Klinik III, Universitätsklinikum Carl Gustav Carus an der Technische Universität Dresden, Dresden, Germany
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Felix Beuschlein
Felix Beuschlein
Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany
Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zürich, Switzerland
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Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zürich, Switzerland
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Introduction Pheochromocytomas and paragangliomas (PPGLs) are neuroendocrine tumors that derive from adrenomedullary tissue (pheochromocytomas) in about 85% of cases and from extra-adrenal chromaffin tissue (paragangliomas) in the remainder
Xinlei Chen
Xinlei Chen
Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Liru Hu
Liru Hu
Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Caojie Liu
Caojie Liu
Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Guangcheng Ni
Guangcheng Ni
Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Yuwei Zhang
Yuwei Zhang
Department of Endocrinology and Metabolism, West China Hospital of Sichuan University, Chengdu, Sichuan, China
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Introduction Pheochromocytoma and paraganglioma (PPGL) are tumors composed of chromaffin cells, which commonly produce one or more catecholamines: epinephrine, norepinephrine and dopamine. These tumors are rarely silent, and they are
