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Introduction Brief history of insulin pens and evolution to connected pens Every person with type 1 diabetes requires insulin to live. Many people with type 2 diabetes also require insulin to achieve glycemic targets due to the progressive
Nilsson F Nobels F J Nyberg R Opitz M Paez Pereda R Paschke T Penning J Petrie D Van der Poorten H Pope H Rakugi H Ramos A M Ramos-Levi L Rejnmark U Renner E Rijntjes R Robeva S V Roeden J A Romijn V C Russo J Rutishauser R Sahay S B Sahin J M Schattenberg
Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA
Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, Oregon, USA
Department of Physiology & Pharmacology, Oregon Health & Science University, Portland, Oregon, USA
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Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA
Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon, USA
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Care and Use Committee and used 14 old (>20 years) female rhesus macaques ( Macaca mulatta ). The animals were housed indoors in pens (3–4 animals per pen) under controlled environmental conditions: 24°C temperature; 12-h light and 12-h darkness
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, Yakutzk, and Yokohama; ‘Come writers and critics, who prophesize with your pen, and keep your eyes wide, the chance won't come again … for the times they are a-changin' ’. The classical peer-review system eventually may need further development, for
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, CGM devices have become interconnected with various apps and other diabetes technology devices including smart insulin pens and insulin pumps. Each major CGM device on the market has its own cloud-based centralized management app that allows for the
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, pubertal failure and are infertile ( 1 , 2 ). In rodents, Kiss1 neurons are primarily located in the arcuate nucleus (Kiss1 ARC ) and the anteroventral periventricular/periventricular nucleus (Kiss1 AVPV/ PeN ) and are deferentially regulated by sex
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same centre using pen devices was 82% ( 21 ). In the present study, which includes both GH treatment-naïve and non-naïve patients, clinically meaningful improvements in growth rates were observed after 1 year of treatment across all GH indications
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Pediatric team of the Clinical Investigation Center 9302/INSERM, Hospital of Children, Toulouse, France
Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), INSERM UMR1291 - CNRS UMR5051 - Université Toulouse III, Toulouse, France
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Patient-Reported Outcomes Unit (PROQOL), UMR 1123, University Paris Cité, INSERM, Paris, France
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Stature Youth. The DCOA1 of the LIQ-GHD covers life interference due to regimen, missed injections, pen ease of use, regimen convenience, benefit/satisfaction/willingness to continue treatment, and injection-related signs/symptoms. The DCOA1 is a
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Vascular Laboratory, Cairo University, Cairo, Egypt
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same skilled sonographer. Endothelial function has been assessed by measuring the percent of change in blood flow following heat-mediated vasodilation using laser Doppler flowmetry (Pen Flux System 5000, Perimed AB) in patients and controls. Skin
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of whole body gross metabolism. Sheep were transferred to individual sawdust-bedded pens placed within the barn, where they were normally housed. The pens allowed for limited physical contact with neighboring sheep through the bars of the pen, and the
