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Li Li, Qifa Song and Xi Yang

exhaustion of pancreatic β-cells ( 1 ). This deficiency in insulin function is the primary cause for developing a metabolically unhealthy status in patients with obesity who usually display impaired glucose tolerance (IGT) and even type 2 diabetic mellitus (T

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Ling Zhou, Zhexin Ni, Wen Cheng, Jin Yu, Shuai Sun, Dongxia Zhai, Chaoqin Yu and Zailong Cai

clinical phenotype in patients with PCOS. Hyperinsulinemia and hyperandrogenism can mutually aggravate each other to form a ‘vicious circle’. Excessive fat storage in obese patients can increase insulin concentration in the blood and trigger and aggravate

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Alexis Sudlow, Carel W le Roux and Dimitri J Pournaras

with obesity who also suffer from gastro-oesophageal reflux. In these patients, RYGB may be a particularly pragmatic choice given its efficacy as a treatment for reflux in its own right. Following any bariatric procedures, there is the risk of

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Volha V Zhukouskaya, Anya Rothenbuhler, Annamaria Colao, Carolina Di Somma, Peter Kamenický, Séverine Trabado, Dominique Prié, Christelle Audrain, Anna Barosi, Christèle Kyheng, Anne-Sophie Lambert and Agnès Linglart

) or percentage with absolute number in parenthesis. BMI-IOTF, Body Mass Index – International Obesity Task Force. In the entire cohort of 172 patients with XLH, the information about genetic analysis was available for 147 patients among

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Karim Gariani, Geneviève Drifte, Irène Dunn-Siegrist, Jérôme Pugin and François R Jornayvaz

been shown that administration of a recombinant form of this hormone in obese mice and diabetic monkeys improves insulin sensitivity, body weight, and lipid profile (9, 10, 11, 12, 13, 14) . Sepsis represents a continuum beginning with a host

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Maria Lola Evia-Viscarra, Edel Rafael Rodea-Montero, Evelia Apolinar-Jiménez and Silvia Quintana-Vargas

compare the clinical, anthropometric, and biochemical characteristics between patients with and without MS by sex. Subjects and methods Participants We conducted a cross-sectional study with a sample of obese adolescents (boys and girls) from 8 to 16 years

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Angela Köninger, Philippos Edimiris, Laura Koch, Antje Enekwe, Claudia Lamina, Sabine Kasimir-Bauer, Rainer Kimmig and Hans Dieplinger

and leads to exaggerated androgen biosynthesis in patients with PCOS in a synergistic manner together with LH (10) . An oral glucose tolerance test (OGTT) is recommended in obese patients with PCOS, but further research is required to detect lean

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Eva Olga Melin, Magnus Hillman and Mona Landin-Olsson

( P  = 0.039). In the non-users of AHD, patients with high systolic BP had higher prevalence of physical inactivity ( P  = 0.009), high MSC ( P  = 0.012), depression ( P  = 0.022), and abdominal obesity ( P  = 0.025). Table 2 Comparisons between

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Hugo R Ramos, Andreas L Birkenfeld and Adolfo J de Bold

of diabetes but it is not yet known if it reduces the risk of cardiovascular events (39, 40, 41, 42, 43, 44, 45, 46) . In patients with severe obesity (BMI >40 kg/m 2 ) before gastric bypass surgery, the median level of NT-proBNP was 54 pg

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A V Dreval, I V Trigolosova, I V Misnikova, Y A Kovalyova, R S Tishenina, I A Barsukov, A V Vinogradova and B H R Wolffenbuttel

Introduction Disturbances of glucose metabolism are frequently observed in patients with acromegaly. In one of the first papers to be published on this topic, abnormal glucose tolerance was found in over 60% of patients with acromegaly (1) . The