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central hospitals who helped gather the tumor samples and patient data. References 1 Talat N Schulte KM . Clinical presentation, staging and long-term evolution of parathyroid cancer . Annals of Surgical Oncology 2010 2156 – 2174
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to shed light on the molecular mechanisms involved in parathyroid cancer development and metastatic spread. Current evidence indicates that the CDC73 , the gene responsible for HPT–JT syndrome, which is characterized by a high prevalence of PC, might
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of PC ( Table 2 ). The ROC curve was used to determine the optimal cut-off value for predicting parathyroid cancer in LMR and tumor size ( Fig. 1 ). Results show that the cut-off value for LMR was 4.857, and the area under the curve (AUC) was 0
Parathyroid Unit – LIM-28, Laboratório de Cirurgia de Cabeça e Pescoço, Division of Head and Neck Surgery, Department of Surgery, Hospital das Clinicas (HCFMUSP), University of São Paulo School of Medicine (FMUSP), Faculdade de Medicina, Universidade de São Paulo, São Paulo, São Paulo, Brazil
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Endocrine Oncology Division, Institute of Cancer of the State of São Paulo (ICESP), University of São Paulo School of Medicine (FMUSP), Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, São Paulo, Brazil
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Endocrine Oncology Division, Institute of Cancer of the State of São Paulo (ICESP), University of São Paulo School of Medicine (FMUSP), Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, São Paulo, Brazil
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exploration as parathyroid disease is mostly multiglandular. Accordingly, the two elective surgical techniques recommended for HPT/MEN1 are total PTx with heterotopic autograft (TPTx+AG) and subtotal PTx (SPTx) ( 2 , 13 , 14 ). Although permanent
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total thyroidectomy with cervical lymph node dissection was performed. Histopathological sections of parathyroid gland and thyroid nodules were reviewed by two independent pathologists. Notably, final pathological reports of thyroid cancer included the
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thyroid surgeons or parathyroid + thyroid surgeons in (A) cancer patients, (B) Graves’ patients and (C) goitre patients over time. (D) Distribution of surgeon over time and hypoparathyroidism from 2012 to 2021. Over time, the risk of hypoPT
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Introduction Primary hyperparathyroidism (PHPT) and malignancy are the two most common causes of hypercalcemia ( 1 ). Hypercalcemic crisis (HC) is an uncommon, but severe complication of PHPT more specifically for parathyroid cancer ( 2 ). The
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the system of American Joint Committee on Cancer (AJCC) (the 7th edition) ( 28 ). The primary endpoints were the number of parathyroid glands identified, autotransplanted and inadvertently removed, incidence of postoperative hypoparathyroidism and
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Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
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Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
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Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
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Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
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Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
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with an increased risk of cardiovascular and cerebrovascular diseases as well as cancer (1, 2, 3) . Parathyroid carcinomas are very rare (<1% of parathyroid tumours), but today's oncological treatment regimens have only a limited effect (4
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carcinoma, atypical parathyroid adenoma, or parathyromatosis? Cancer 2007 255 – 264 . ( https://doi.org/10.1002/cncr.22790 ) 29 Baskin HJ . New applications of thyroid and parathyroid ultrasound . Minerva Endocrinologica 2004 195 – 206 . 30