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digestive tract, including 59 with tumours located in the pancreas and 72 with lesions in the small intestine, caecum and appendix (midgut – the tumours originating from the central part of the archenteron) and in the colon (hindgut – tumours of the
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–88 years (median age, 65 years). Lesions were located in the pancreas in 82 patients, in the small intestine in 75 patients, in the rectum in 14 patients and in the stomach in 8 patients. According to the current 2019 World Health Organization (WHO
Department of Endocrinology, Diabetes and Metabolic Diseases, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France
Centre d’Investigation Clinique (CIC-CRB)-INSERM 1404, Rouen University Hospital, Rouen, France
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Department of Endocrinology, Diabetes and Metabolic Diseases, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France
Centre d’Investigation Clinique (CIC-CRB)-INSERM 1404, Rouen University Hospital, Rouen, France
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Department of Endocrinology, Diabetes and Metabolic Diseases, Normandie Univ, UNIROUEN, Rouen University Hospital, Rouen, France
Centre d’Investigation Clinique (CIC-CRB)-INSERM 1404, Rouen University Hospital, Rouen, France
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Introduction Glucose homeostasis is a crucial parameter to maintain normal body function. Control of blood glucose levels is ensured by a highly sophisticated network of various hormones released by the pancreas, intestine, liver, adipose and
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Introduction Pancreas agenesis (PA) is a very rare condition that causes permanent neonatal diabetes mellitus (PNDM) and pancreatic exocrine insufficiency. It presents most commonly with neonatal hyperglycemia in small for gestational age
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( Table 1 ). Larger tumours were significantly more likely to originate from the tail of the pancreas ( P = 0.009) and to present with distant metastases ( P = 0.001). Table 1 Demographics and pre-operative characteristics of patients
Faculty of Medicine, University of Oslo, Oslo, Norway
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Department of Pharmacy, University of Oslo, Oslo, Norway
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Faculty of Medicine, University of Oslo, Oslo, Norway
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Department of Behavioural Medicine, University of Oslo, Oslo, Norway
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Centre of Excellence-HTH, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
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Faculty of Medicine, University of Oslo, Oslo, Norway
Metabolic and Renal Research Group, Faculty of Health Sciences, UiT-The Arctic University of Norway, Tromsø, Norway
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Introduction Transplantation has become an established treatment option for selected patients with type 1 diabetes in many centres. Simultaneous pancreas and kidney (SPK) transplantation was offered to the first patient in history in Minnesota
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Department of General Surgery, Xiangya Hospital, Central South University, Changsha, China
Department of Burns and Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China
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= 14), paraffin-embedded tissue ( n = 20) as well as serum ( n = 76) from patients with pNEN were obtained from the Pancobank of the European Pancreas Center (EPZ/Department of Surgery, University Hospital Heidelberg; Ethical Approval Votes no. 301
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European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
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, with the incidence rate increasing approximately 4.6-fold from 1973 (0.18 per 100,000) to 2012 (0.82 per 100,000) in the United States ( 1 , 2 , 3 ). PNEN is a clinically rare and heterogeneous disease of the pancreas with variable clinical
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Fig. 3A. Fat pad weights were expressed as the percentage of body weight ( Table 1 ). Table 1 Adiposity and pancreas morphometric data of Virgin, L0 and L21 mice. Virgin L0 L21 Inguinal fat pad (% of body weight) 1
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pancreas. A small percentage of affected patients (<10%) are classified as type 1B, with no evidence of autoimmunity and the pathogenesis in these cases is considered idiopathic ( 1 , 2 ). The aim of this comprehensive review is to present updated