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Arpna Sharma, Vijay Simha Baddela, Frank Becker, Dirk Dannenberger, Torsten Viergutz and Jens Vanselow

). Catabolism and mobilization of stored triglycerides lead to increased systemic concentrations of non-esterified fatty acids (NEFA) like palmitic acid (PA, C16:0), stearic acid (SA, C18:0), oleic acid (OA, C18:1) and of β-hydroxybutyric acid (BHBA) ( 2 ). Such

Open access

Selina Mäkinen, Yen H Nguyen, Paulina Skrobuk and Heikki A Koistinen

Accuri C6 (BD Biosciences, San Jose, CA, USA). The dye was excited at 488 nm, and fluorescent emission was collected through FL3 channel. Reagents Trypsin, FBS, penicillin/streptomycin, low-glucose DMEM, l -glutamine, palmitic acid, oleic acid

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Leanne Hodson and Fredrik Karpe

extraction ( 5 , 12 ). In vitro work using primary rat hepatocytes demonstrated that specific fatty acids (oleic, palmitic, stearic, palmitoleic, and eicosapentaenoic acids) were equally effective, in a concentration-dependent manner, at reducing the