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fatty acids (FFAs) ( 1 , 2 , 3 , 4 ). FFAs are an energy source, and induce activation of signal transduction pathways in breast cancer cells ( 5 , 6 , 7 , 8 ). Particularly, oleic acid (OA) induces proliferation, migration and invasion of breast
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). Catabolism and mobilization of stored triglycerides lead to increased systemic concentrations of non-esterified fatty acids (NEFA) like palmitic acid (PA, C16:0), stearic acid (SA, C18:0), oleic acid (OA, C18:1) and of β-hydroxybutyric acid (BHBA) ( 2 ). Such
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higher BMI ( P < 0.001) and HOMA-IR ( P = 0.017). The concentrations of myristic, palmitic, stearic, palmitoleic, oleic and linoleic acids were all significantly higher ( P < 0.001) in those with steatosis while the level of arachidonic acid was
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and the box plots of the top nine differential metabolites were plotted further ( Fig. 4C and D ). These nine metabolites were indole-2-propionic acid, carnitine oleate, indolinic acid, tyrosine, creatine, oleic acid, glycine, 10Z-nonadecanoic acid
University of Helsinki, Department of Medicine, and Abdominal Center, Endocrinology, Helsinki University Central Hospital, Helsinki, Finland
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University of Helsinki, Department of Medicine, and Abdominal Center, Endocrinology, Helsinki University Central Hospital, Helsinki, Finland
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University of Helsinki, Department of Medicine, and Abdominal Center, Endocrinology, Helsinki University Central Hospital, Helsinki, Finland
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University of Helsinki, Department of Medicine, and Abdominal Center, Endocrinology, Helsinki University Central Hospital, Helsinki, Finland
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Accuri C6 (BD Biosciences, San Jose, CA, USA). The dye was excited at 488 nm, and fluorescent emission was collected through FL3 channel. Reagents Trypsin, FBS, penicillin/streptomycin, low-glucose DMEM, l -glutamine, palmitic acid, oleic acid
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extraction ( 5 , 12 ). In vitro work using primary rat hepatocytes demonstrated that specific fatty acids (oleic, palmitic, stearic, palmitoleic, and eicosapentaenoic acids) were equally effective, in a concentration-dependent manner, at reducing the
Department of Endocrinology, Department of Molecular Medicine and Surgery, Metabolism and Diabetology, Karolinska University Hospital, 171 76 Stockholm, Sweden
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(Student's t -test) identified seven annotated metabolites as being significantly different during GH treatment. Some incompletely identified compounds and guanosine decreased, whereas lysine, hexadecanoic acid (C16:0), oleic acid (C18:1), and one
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Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
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Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark
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of oleic acid, 9.1 kcal/g is the caloric density. Plasma FFA oxidation rate (kcal/day) = (palmitate oxidation (µmol/min) × 1440 min × 256.42 g/mol × 9.1 kcal/g)/ (0.29 × 1,000,000), where 0.29 is the average ratio of palmitate in TG long chain FA
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adipose tissue in humans is oleic acid, a monounsaturated fatty acid that is assigned to omega 9 fatty acids based on the location of their double bond. The amount of fat tissue in the bodyweight of a normal-weight horse is 5% (18) . There are currently
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Shrivastava D Tantry MN Tantry BA Oleuropein and oleic acid: a novel emerging dietary target for human chronic diseases . Indian Journal of Biochemistry and Biophysics 2019 56 263 – 268 . 14 Pantham P Aye ILH Powell TL Inflammation in