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M Jensterle, A Podbregar, K Goricar, N Gregoric, and A Janez

Introduction Obesity causes functional hypogonadism (FH) due to suppression of hypothalamus-pituitary-testicular (HPT) axis that is potentially reversible ( 1 ). Recent evidence suggests that weight reduction (WR) with lifestyle measures (LSMs

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Anru Wang, Xueqin Yan, Cai Zhang, Caiqi Du, Wenjun Long, Di Zhan, and Xiaoping Luo

Introduction The worldwide prevalence of obesity among children and adolescents has increased in past years ( 1 ). Obesity is associated with insulin resistance, type 2 diabetes mellitus (T2DM) and long-term cardiovascular complications

Open access

L Bahler, H J Verberne, E Brakema, R Tepaske, J Booij, J B Hoekstra, and F Holleman

. Recently, a quick release variant of bromocriptine has emerged as a new glucose-lowering treatment in obese patients with type 2 diabetes mellitus. Bromocriptine is a centrally acting dopamine D 2 -receptor agonist, but it also weakly stimulates the

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Frederique Van de Velde, Marlies Bekaert, Anja Geerts, Anne Hoorens, Arsène-Hélène Batens, Samyah Shadid, Margriet Ouwens, Yves Van Nieuwenhove, and Bruno Lapauw

Introduction An important complication of obesity is the development of nonalcoholic fatty liver disease (NAFLD), which covers a broad histological spectrum from simple steatosis to nonalcoholic steatohepatitis (NASH), and can progress to

Open access

Eliana Piantanida, Daniela Gallo, Giovanni Veronesi, Eugenia Dozio, Eugenia Trotti, Adriana Lai, Silvia Ippolito, Jessica Sabatino, Maria Laura Tanda, Antonio Toniolo, Marco Ferrario, and Luigi Bartalena

calcium along with an increase in adipocyte fatty acid synthase and glycerol-3-phosphate dehydrogenase activities and lipolysis inhibition ( 28 ). Metabolic syndrome (MetS) is a multifactorial condition, having central obesity as a causative factor

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Aneta Gawlik, Michael Shmoish, Michaela F Hartmann, Stefan A Wudy, Zbigniew Olczak, Katarzyna Gruszczynska, and Ze’ev Hochberg

Introduction Nonsyndromic childhood obesity is associated with nonalcoholic fatty liver disease (NAFLD), a spectrum of conditions, ranging from steatosis to nonalcoholic steatohepatitis (NASH), and various degrees of fibrosis and cirrhosis ( 1

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Karolien Van De Maele, Jean De Schepper, Jesse Vanbesien, Monique Van Helvoirt, Ann De Guchtenaere, and Inge Gies

Introduction Obese adolescents are a population known to be at risk for vitamin D deficiency, which is defined as a serum 25-OH-D level below 20 µg/L according to the guidelines set by the Endocrine Society (based on the Institute Of Medicine

Open access

Maria Giannakou, Katerina Saltiki, Emily Mantzou, Eleni Loukari, Georgios Philippou, Konstantinos Terzidis, Charalampos Stavrianos, Miltiades Kyprianou, Theodora Psaltopoulou, Kalliopi Karatzi, and Maria Alevizaki

high oxidative stress is further influenced by obesity and dietary habits in euthyroid women with Hashimoto thyroiditis. Materials and methods This cross-sectional study was conducted in Greece; it involved 218 consecutive euthyroid women with

Open access

Maria Lola Evia-Viscarra, Edel Rafael Rodea-Montero, Evelia Apolinar-Jiménez, and Silvia Quintana-Vargas

Introduction A sedentary lifestyle and a diet rich in carbohydrates and fats during childhood leads to obesity. In Mexico, the National Health and Nutrition Survey 2012 data estimate a high prevalence of obesity, defined as a BMI ≥ the 95th

Open access

Jay Toulany, Sebastian D Parlee, Christopher J Sinal, Kathryn Slayter, Shelly McNeil, and Kerry B Goralski

Introduction After characterisation as an adipokine by our group in 2007, research concerning chemerin and its relationship to obesity has risen steadily. Chemerin is secreted as an inactive precursor prochemerin, which undergoes processing at