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Nadia Sawicka-Gutaj Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Ariadna Zybek-Kocik Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Michał Kloska Lehigh Valley Health Network, Department of Medicine, Lehigh Valley Hospital – Cedar Crest, Allentown, USA

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Paulina Ziółkowska Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Agata Czarnywojtek Department of Pharmacology, Poznan University of Medical Sciences, Poznan, Poland

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Jerzy Sowiński Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Dorota Mańkowska-Wierzbicka Department of Gastroenterology, Internal Medicine, Metabolic Diseases and Dietetics, Poznan University of Medical Sciences, Poznan, Poland

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Marek Ruchała Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, Poznan, Poland

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Introduction The adipose tissue is a well-established source of multiple circulating peptides that are responsible for various metabolic effects ( 1 ). Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) has been recently recognized as an

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Nese Cinar Department of Endocrinology and Metabolism, Hacettepe University School of Medicine, 06100 Sihhiye, Ankara, Turkey

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Alper Gurlek Department of Endocrinology and Metabolism, Hacettepe University School of Medicine, 06100 Sihhiye, Ankara, Turkey

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also called nicotinamide phosphoribosyltransferase (NAMPT) because of its functional and biochemical homology with NAD biosynthesized from nicotinamide (58) . Fukuhara et al . (59) used the term ‘visfatin’ for this protein due to its predominant

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Davoud Jafari-Gharabaghlou Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

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Mostafa Vaghari-Tabari Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

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Hajar Oghbaei Department of Physiology, Tabriz University of Medical Sciences, Tabriz, Iran

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Laura Lotz Department of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen–Nürnberg, Erlangen, Germany

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Reza Zarezadeh Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

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Yeganeh Rastgar Rezaei Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran

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Mahnaz Ranjkesh Medical Radiation Science Research Group (MRSRG), Tabriz University of Medical Sciences, Tabriz, Iran

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Mohammad Nouri Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran

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Amir Fattahi Department of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen–Nürnberg, Erlangen, Germany
Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

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Saba Nikanfar Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

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Ralf Dittrich Department of Obstetrics and Gynecology, Erlangen University Hospital, Friedrich-Alexander University of Erlangen–Nürnberg, Erlangen, Germany

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phosphoribosyltransferase (NAMPT) functionally acts as an enzyme restricting the conversion of nicotinamide to nicotinamide mononucleotide (NMN) which subsequently activates the synthesis of nicotinamide adenine dinucleotide (NAD+) and thus plays a regulatory role in the

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Xu Chen Department of Toxicology, School of Public Health, Sun Yat-sen University, Guangzhou, People’s Republic of China
Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou, People’s Republic of China

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Yi Tang Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou, People’s Republic of China

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Shen Chen Department of Toxicology, School of Public Health, Sun Yat-sen University, Guangzhou, People’s Republic of China

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Wenhua Ling Department of Nutrition, School of Public Health, Sun Yat-Sen University, Guangzhou, People’s Republic of China
Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Guangzhou, People’s Republic of China

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Qing Wang Department of Toxicology, School of Public Health, Sun Yat-sen University, Guangzhou, People’s Republic of China
Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Guangzhou, People’s Republic of China

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M Gholami A Hosseinzadeh P Keyvani H Shidfar F Zamani F . Association between nicotinamide phosphoribosyltransferase and de novo lipogenesis in nonalcoholic fatty liver disease . Medical Principles and Practice 2017 26 251 – 257 . ( https

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Anne H van der Spek Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands

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Olga V Surovtseva Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands

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Saskia Aan Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands

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Anton T J Tool Sanquin Research and Landsteiner Laboratory, Academic Medical Center, Amsterdam, The Netherlands

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Annemarie van de Geer Sanquin Research and Landsteiner Laboratory, Academic Medical Center, Amsterdam, The Netherlands

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Korcan Demir Division of Pediatric Endocrinology, Dokuz Eylül University, Izmir, Turkey

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Anja L M van Gucht Department of Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands

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A S Paul van Trotsenburg Department of Pediatric Endocrinology, Academic Medical Center, Amsterdam, The Netherlands

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Timo K van den Berg Sanquin Research and Landsteiner Laboratory, Academic Medical Center, Amsterdam, The Netherlands

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Eric Fliers Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands

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Anita Boelen Department of Endocrinology and Metabolism, Academic Medical Center, Amsterdam, The Netherlands

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preexisting database of healthy controls ( n  = 32 for E. coli and n  = 36 for S. aureus ). Neutrophil NADPH oxidase activity and chemotaxis Nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase) activity was measured as described

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