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Introduction Myo-inositol (MI) is one stereoisomer of a C 6 sugar alcohol that belongs to the inositol family ( 1 ). It is the precursor of inositol triphosphate, acting as an intracellular second messenger and regulating a number of hormones
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M Victor VM . Mitochondrial dynamics in type 2 diabetes: pathophysiological implications . Redox Biology 2017 637 – 645 . ( https://doi.org/10.1016/j.redox.2017.01.013 ) 22 Sun L Dutta RK Xie P Kanwar YS . Myo-inositol oxygenase
Department of Clinical Research, University of Basel, Basel, Switzerland
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osmolytes (e.g. glutamine and other aminoacids, glutamate, taurine, myo-inositol, etc.) are synthetized or shifted into ICF, and the previously internalized potassium is released back to extracellular fluid (ECF). As adaption to a chronic hyperosmolar state
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. ( https://doi.org/10.1089/ars.2016.6665 ) 35 Deng F Sharma I Dai Y Yang M Kanwar YS . myo-inositol oxygenase expression profile modulates pathogenic ferroptosis in the renal proximal tubule . Journal of Clinical Investigation 2019 129 5033