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Neil R Chappell, Beth Zhou, Amy K Schutt, William E Gibbons and Chellakkan S Blesson

controls and n  = 6 in lean PCOS, * P  < 0.05). Lipid peroxidation was similar between the control and PCOS oocytes Lipid peroxidation was measured using BODIPY, a dye used to measure lipid peroxidation. Mitochondria are a major site of

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Flavia Letícia Martins Peçanha, Reinaldo Sousa dos Santos and Wagner Seixas da-Silva

specifically through a mitochondria binding motif ( 10 ). This mitochondrial interaction occurs through the voltage-dependent anion channel (VDAC), also known as the mitochondrial porin, which is an integral protein of the mitochondrial outer membrane ( 17

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Madalena von Hafe, João Sergio Neves, Catarina Vale, Marta Borges-Canha and Adelino Leite-Moreira

+ channel (mitoKATP) in rescued mitochondria ( 27 ). T3 replacement after myocardial infarction might offer a highly successful therapeutic strategy to improve myocardial mitochondrial function and cardiac cell metabolism, limiting infarct-scar size and

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T S Nilsen, L Thorsen, C Kirkegaard, I Ugelstad, S D Fosså and T Raastad

. Biochemical Journal 1980 192 349 – 353 . ( doi:10.1042/bj1920349 ) 8 Jezek P Hlavata L. Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism . International Journal of Biochemistry & Cell Biology 2005 37

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Yiqiong Ma, Zhaowei Chen, Yu Tao, Jili Zhu, Hongxia Yang, Wei Liang and Guohua Ding

). Furthermore, mitochondria are considered dynamic organelles that periodically divide (fission) and fuse (fusion) ( 11 ). These dynamic processes maintain stable mitochondrial mass and quantity ( 12 ). It was reported that hyperglycaemia results in increased

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Tingting Shu, Zhigang Lv, Yuchun Xie, Junming Tang and Xuhua Mao

mitochondria via the ion transporter mitochondrial substrate carrier family protein (Mcfu) ( 17 , 18 ). As a divalent positively charged ion, Fe 2+ depolarizes the mitochondria membrane potential, resulting in a disruption of the electron transport chain (ETC

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Magdalene K Montgomery and Nigel Turner

Mitochondrial function Mitochondria, originating from bacterial precursor cells that were able to generate energy, provide a platform for the generation of ATP, the energy currency of the cell. As ATP is essential for many cellular processes

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Chanyang Kim and Seungjoon Park

mitochondrial membrane potential (∆ψ M ) and the release of cytochrome c from the mitochondria into the cytoplasm ( 4 ). Upon entry into the cytosol, cytochrome c complexes with the caspase-activating protein Apaf-1, leading to the activation of apoptotic

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Michaela Keuper

is accumulating evidence that ATMΦ enhances or suppresses the mitochondrial function in WAT. The understanding of how adipocyte energy metabolism and mitochondria are regulated during physiological and pathophysiological adaptation requires the

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Lianghui You, Yan Wang, Yao Gao, Xingyun Wang, Xianwei Cui, Yanyan Zhang, Lingxia Pang, Chenbo Ji, Xirong Guo and Xia Chi

. White adipose tissue (WAT) is specialized for the energy storage in form of triglyceride. In contrast, brown adipose tissue (BAT) possesses a large amount of uncoupling protein 1 ( Ucp1 ) in mitochondria ( 1 ). Experiments in mouse models have