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Introduction In 2023, international authorities adopted the nomenclature metabolic dysfunction-associated steatotic liver disease (MASLD), which was originally referred to as non-alcoholic fatty liver disease (NAFLD) ( 1 ). The estimated
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Department of Zoology, Islamia College Peshawar (CU), Peshawar, Pakistan
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DZHK (German Centre for Cardiovascular Research), Partner Site Greifswald, University Medicine, Greifswald, Germany
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associated with these two outcomes ( Fig. 2 ). The fT3/fT4 ratio was also positively associated with liver fat content and NAFLD. Table 2 Associations of thyroid function parameters with liver fat content and non-alcoholic fatty liver disease (NAFLD
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, cardiovascular disease, and metabolic disorders including NAFLD ( 4 ). ER stress in the liver and NAFLD is closely associated with the development of hepatic insulin resistance ( 5 ). Our interests are focused on the role of the HSR in metabolic diseases and
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comprehensive workup of all components of the metabolic syndrome and systematic exclusion of competing aetiologies of liver dysfunction ( Table 1 ) ( 29 ). If symptoms are present, they are of non-specific nature, such as fatigue, mild right upper quadrant pain