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Shenglong Le, Leiting Xu, Moritz Schumann, Na Wu, Timo Törmäkangas, Markku Alén, Sulin Cheng and Petri Wiklund

at the 7.5-year follow-up assessments, respectively. The age at menarche was defined as the first onset of menstrual bleeding reported by questionnaire or phone call during the follow-up. Time relative to menarche (TRM, in months) was defined as the

Open access

Elin Kahlert, Martina Blaschke, Knut Brockmann, Clemens Freiberg, Onno E Janssen, Nikolaus Stahnke, Domenika Strik, Martin Merkel, Alexander Mann, Klaus-Peter Liesenkötter and Heide Siggelkow

parameters, parents, and menarche were collected from the adult patients’ medical records. Ethics consideration The study was approved by the Local Ethics Committee in Goettingen (18/2/07) and conformed to the Declaration of Helsinki, allowing the use

Open access

Rui-yi Tang, Rong Chen, Miao Ma, Shou-qing Lin, Yi-wen Zhang and Ya-ping Wang

characteristics and menarche) after the age of 16 years, low oestradiol (E 2 ) concentrations and low or inappropriately normal serum gonadotropin concentrations ( 9 ). All patients had normal results for other pituitary hormones, prolactin, thyroid

Open access

Monica F Stecchini, Zilda Braid, Candy B More, Davi C Aragon, Margaret Castro, Ayrton C Moreira and Sonir R Antonini

fast puberty (EFP) ( 40 , 41 ). Precocious menarche was defined as cyclic vaginal bleeding before 9 years ( 1 ). CPP and EFP were considered pubertal disorders. Sex, age, duration of ACT signs, Tanner stage for pubic hair, stature SDS, Δ BA, tumor

Open access

Juliane Léger, Anne Fjellestad-Paulsen, Anne Bargiacchi, Catherine Doyen, Emmanuel Ecosse, Jean-Claude Carel and Marie-France Le Heuzey

status (Tanner stage) Age at menarche A B C A B C A B C A B C 1 14.2 18.7* 20.7 149.9 165.5 166.5 −1.2 −1.4 −1.8 1 3*** 3 No menarche 2 13.1 15.5 16.3 145.7 155.6 156

Open access

Anastasia K Armeni, Konstantinos Assimakopoulos, Dimitra Marioli, Vassiliki Koika, Euthychia Michaelidou, Niki Mourtzi, Gregoris Iconomou and Neoklis A Georgopoulos

, menarche, age of first intercourse and also number of sexual partners were included in the questionnaires. Study of genetic polymorphisms DNA extraction was conducted by leukocytes of peripheral blood using the method of phenol. Study of rs2234693(T

Open access

Shota Dzemaili, Jitske Tiemensma, Richard Quinton, Nelly Pitteloud, Diane Morin and Andrew A Dwyer

CHH diagnosis was compared to a population-based sample for age of menarche ( 25 ). Analysis Descriptive statistics were used to present survey data. Comparisons between groups were performed using Student’s t -test or Mann–Whitney rank

Open access

R Solomon-Zemler, L Basel-Vanagaite, D Steier, S Yakar, E Mel, M Phillip, L Bazak, D Bercovich, H Werner and L de Vries

596 NA Co-morbidities Colonic polyps Colonic polyps None Neurocognitive function Normal Normal Normal The patient’s mother was born with a birth weight of 1100 g (−4.3 SDS) at 40 weeks of gestation. Her menarche

Open access

Elena Galazzi, Paolo Duminuco, Mirella Moro, Fabiana Guizzardi, Nicoletta Marazzi, Alessandro Sartorio, Sabrina Avignone, Marco Bonomi, Luca Persani and Maria Teresa Bonati

finger camptodactyly and hypoplasia of the left fifth finger distal phalanx ( Fig. 2M ). His mother (II-2), who reported late menarche (at 14 years), had an asymmetric right ulnar deformity and left breast hypoplasia, with other phenotypic features

Open access

Xiujuan Su, Yan Zhao, Zhijuan Cao, Yingying Yang, Tony Duan and Jing Hua

significant difference in maternal age, menarche age, newborn sex or family history of chronic diseases between the euthyroid and IMH groups ( P >0.05) ( Table 1 ). Table 1 Basic characteristic of the population between euthyroid and IMH