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Sheila Leone, Lucia Recinella, Annalisa Chiavaroli, Claudio Ferrante, Giustino Orlando, Michele Vacca, Roberto Salvatori, and Luigi Brunetti

levels decrease with aging, and the possibility that the GHRH/GH/IGF-1 axis is involved in age-related cognitive deficits is suggested by several studies ( 2 , 3 , 4 ). Accordingly, in rodents, the age-related decline in spatial and reference memory is

Open access

Fan Zhang, Jian Chen, Xinyue Lin, Shiqiao Peng, Xiaohui Yu, Zhongyan Shan, and Weiping Teng

memory dysfunction ( 2 , 3 , 4 , 5 ). We previously found that decreased activation of the cAMP response element-binding protein signaling pathway in pups was related to impaired cognitive function caused by maternal SCH ( 6 ). However, the

Open access

Lukas Engler, Christian Adolf, Daniel A Heinrich, Anna-Katharine Brem, Anna Riester, Anna Franke, Felix Beuschlein, Martin Reincke, Axel Steiger, and Heike Künzel

, 4 ); however, the underlying pathophysiology is not fully clarified. Animal data emphasize the importance of a balanced MR/glucocorticoid receptor (GR) system for cognitive functions ( 5 ) and support the role of MR in memory functions. Furthermore

Open access

Lin Ji, Huan-Tong Wu, Xiao-Yan Qin, and Rongfeng Lan

(BDNF) secretion from cortical neurons ( 7 ), low bone mineral density and deficits in learning and memory ( 15 ). Therefore, pathophysiological conditions observed in Cpe fat /Cpe fat mice and Cpe KO mice suggest that CPE plays a variety of roles in

Open access

Emmanuelle Motte, Anya Rothenbuhler, Stephan Gaillard, Najiba Lahlou, Cécile Teinturier, Régis Coutant, and Agnès Linglart

similar to those previously reported, i.e., non-specific digestive symptoms, concentration or memory problems, exhaustion and adrenal insufficiency. One individual, who had a high plasma concentration of mitotane, developed acute severe hepatitis with

Open access

Elena V Varlamov, Dan Alexandru Niculescu, Swechya Banskota, Simona Andreea Galoiu, Catalina Poiana, and Maria Fleseriu

(35.6%), snoring (32.9%), memory loss (29.2%), frontal bossing (25%), hirsutism (25%), jaw changes (24.5%), excessive sweating (23.6%), coarse facies (21.8%), skin tags (21.3%), carpal tunnel syndrome (20.4%), round face (19.4%), back neck pain (19

Open access

Janaína Felix Braga, Daniela Ravizzoni Dartora, Natalia Alenina, Michael Bader, and Robson Augusto Souza Santos

kidney ( 3 ). A relevant part of this new understanding is derived from the phenotypic characterization of Mas-deficient mice in a variety of models, tissues and conditions, including the cardiovascular system ( 4 ), liver ( 5 ), testis ( 6 ), memory

Open access

Elena Valassi, Iacopo Chiodini, Richard A Feelders, Cornelie D Andela, Margueritta Abou-Hanna, Sarah Idres, and Antoine Tabarin

.3 Depression/mood problems 58.8 48.1 Muscle weakness 57.8 43.4 Anxiety 54.1 39.1 Hypertension 52.5 22.2 Loss of concentration 45.0 28.4 Memory problems 41.9 30.3 Menstrual disturbances 35.6 12

Open access

Caroline Culen, Diana-Alexandra Ertl, Katharina Schubert, Lisa Bartha-Doering, and Gabriele Haeusler

involved, classification skills improve, egocentric view is over, viewpoints of others can be taken in account – Ask for achievements in school – when difficulties are reported, organize specific support – Specific risk of impairment in visual memory

Open access

Jane Fletcher, Emma L Bishop, Stephanie R Harrison, Amelia Swift, Sheldon C Cooper, Sarah K Dimeloe, Karim Raza, and Martin Hewison

actions of 1,25D during antigen presentation is to better facilitate the development of memory T cells. Inflammatory stimuli are required to activate DC to enable antigen presentation and subsequent expansion of effector T cells and the development of