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Ram P Narayanan, Bo Fu, Adrian H Heald, Kirk W Siddals, Robert L Oliver, Julie E Hudson, Antony Payton, Simon G Anderson, Anne White, William E R Ollier and J Martin Gibson

and IGFBP3 were not normally distributed, their values were log-transformed for t -test purposes. All other variables studied followed a normal distribution. Linear mixed-effect regression analysis was used to study the longitudinal trends in eGFR as

Open access

Nicola Tufton, Lucy Shapiro, Anju Sahdev, Ajith V Kumar, Lee Martin, William M Drake, Scott A Akker and Helen L Storr

performed a review of the published literature. In parallel we undertook detailed analysis of our paediatric SDHB cohort of both index cases and asymptomatic carriers to provide longitudinal data on clinical outcomes. Based on these combined data, we

Open access

Volha V Zhukouskaya, Anya Rothenbuhler, Annamaria Colao, Carolina Di Somma, Peter Kamenický, Séverine Trabado, Dominique Prié, Christelle Audrain, Anna Barosi, Christèle Kyheng, Anne-Sophie Lambert and Agnès Linglart

). Based on the putative role of phosphate in metabolic syndrome and the permanent abnormal phosphate level observed in XLH children, we performed a longitudinal observational study to investigate the anthropometric parameters of overweight and obesity and

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Eugenie S Lim, Shanty G Shah, Mona Waterhouse, Scott Akker, William Drake, Nick Plowman, Daniel M Berney, Polly Richards, Ashok Adams, Ewa Nowosinska, Carmel Brennan and Maralyn Druce

Patient data were collected and recorded by retrospective review of patient records, searching first for all patients with DTC treated with remnant ablation following thyroidectomy and included for further analysis if histopathology from thyroidectomy was

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Jia Liu, Min Liu, Zhe Chen, Yumei Jia and Guang Wang

quantitatively evaluate the degree of thyroid destruction ( 3 ). Recently, MRI has been increasingly used for identifying thyroid diseases ( 4 , 5 , 6 , 7 , 8 , 9 ). Longitudinal relaxation time mapping (T1-mapping) measured by MRI is a new technique for

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C Sui, Q He, R Du, D Zhang, F Li, G Dionigi, N Liang and H Sun

analysis We retrieved baseline and clinical characteristics, including age at diagnosis, sex, maximum tumor diameter (MTD), multifocality, capsular invasion, thyroiditis, and nodular goiter. We categorized patients based on various LN characteristics

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Roberto Cosimo Melcangi, Livio Casarini, Marco Marino, Daniele Santi, Samantha Sperduti, Silvia Giatti, Silvia Diviccaro, Maria Grimoldi, Donatella Caruso, Guido Cavaletti and Manuela Simoni

underwent both blood and CSF sampling for SRDA51 and SRDA52 gene promoter methylation analysis. The control group included 18 healthy individuals who underwent spinal anaesthesia for planned orthopaedic surgery of the lower limb at the San Gerardo

Open access

Daiki Kobayashi, Nagato Kuriyama, Keita Hirano, Osamu Takahashi and Hiroshi Noto

time-dependent HbA1c levels among diabetic patients. Methods We conducted a retrospective longitudinal study at St. Luke’s International Hospital, Tokyo, Japan, from 2006 to 2016. We included diabetic patients who were 50 years or older male and

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Kristin Ottarsdottir, Anna G Nilsson, Margareta Hellgren, Ulf Lindblad and Bledar Daka

, 1282 men were included in the baseline study. All participants with valid values in all variables used as covariates in the model were included (baseline N  = 1282, follow-up N  = 546, longitudinal analysis N  = 578) ( Fig. 1 ). The mean age at

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Shenglong Le, Leiting Xu, Moritz Schumann, Na Wu, Timo Törmäkangas, Markku Alén, Sulin Cheng and Petri Wiklund

peripubertal children. Our study has both strengths and limitations. The longitudinal analysis was conducted in a homogenous nationally representative cohort of healthy females followed from childhood across puberty into early adulthood with several follow