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Liza Haqq, James McFarlane, Gudrun Dieberg and Neil Smart

published papers continued up until April 30, 2013. Inclusions Randomised, controlled trials of exercise-alone or lifestyle (exercise plus diet) intervention in people with PCOS were included. There were no language restrictions. Exclusions Animal studies

Open access

Alexis Sudlow, Carel W le Roux and Dimitri J Pournaras

-Schubert KE , et al . Gastric bypass surgery vs intensive lifestyle and medical intervention for type 2 diabetes: the CROSSROADS randomised controlled trial . Diabetologia 2016 945 – 953 . ( https://doi.org/10.1007/s00125-016-3903-x ) 15 Parikh M

Open access

Anru Wang, Xueqin Yan, Cai Zhang, Caiqi Du, Wenjun Long, Di Zhan and Xiaoping Luo

non-IR group ( n  = 26). Obese children and adolescents whose weight change more than 5% after 6 months of lifestyle intervention were included in subsequent studies. Those individuals treated with medications or weight loss less than 5% were

Open access

Thomas Reinehr, Alexandra Kulle, Juliane Rothermel, Caroline Knop-Schmenn, Nina Lass, Christina Bosse and Paul-Martin Holterhus

using an LC–MS/MS steroid profiling method ( 7 ) in obese adolescent girls with PCOS participating in a lifestyle intervention. Subjects and methods The Local Ethics Committee of the University of Witten/Herdecke approved this study. Written

Open access

Johan Verhelst, Anders F Mattsson, Cecilia Camacho-Hübner, Anton Luger and Roger Abs

normality independently of any condition. The other one, metabolic disruption, could be prevented by timely diagnosis of GHD and treated by adequate GH replacement, but it will also require a lifestyle intervention, physical activity and especially weight

Open access

Hamidreza Mani, Yogini Chudasama, Michelle Hadjiconstantinou, Danielle H Bodicoat, Charlotte Edwardson, Miles J Levy, Laura J Gray, Janette Barnett, Heather Daly, Trevor A Howlett, Kamlesh Khunti and Melanie J Davies

). It is suggested that such psychological factors are potential barriers for successful lifestyle interventions and require further addressing ( 9 ). It is therefore possible to assume that provision of an education programme like our study, at an

Open access

Mardia López-Alarcón, Jessie N Zurita-Cruz, Alonso Torres-Rodríguez, Karla Bedia-Mejía, Manuel Pérez-Güemez, Leonel Jaramillo-Villanueva, Mario E Rendón-Macías, Jose R Fernández and Patricia Martínez-Maroñas

. ( https://doi.org/10.1210/en.2010-0556 ) 44 Wei C Candler T Crowne E Hamilton-Shield JP . Interval outcomes of a lifestyle weight-loss intervention in early adolescence . Children 2018 E77 . ( https://doi.org/10.3390/children5060077 ) 45

Open access

Monika Karczewska-Kupczewska, Agnieszka Nikołajuk, Radosław Majewski, Remigiusz Filarski, Magdalena Stefanowicz, Natalia Matulewicz and Marek Strączkowski

their insulin sensitivity after the dietary intervention program. Subjects with lower initial insulin sensitivity achieved greater metabolic benefit from lifestyle intervention ( 29 ). Findings similar to ours regarding worsening ( 29 , 30 ), or the

Open access

Mirjam M Oosterwerff, Rosa Meijnen, Natasja M Van Schoor, Dirk L Knol, Mark H H Kramer, Mireille N M Van Poppel, Paul Lips and E Marelise W Eekhoff

physical activity guidelines, a lifestyle intervention could be essential for the health of overweight non-western immigrants. When 25(OH)D concentrations were >60 nmol/l after intervention, there was borderline improvement of physical exercise capacity in

Open access

Malin Nylander, Signe Frøssing, Caroline Kistorp, Jens Faber and Sven O Skouby

risk of VTE in PCOS. Lifestyle intervention and metformin are mainstays in the treatment of PCOS, aiming at reducing body weight and insulin resistance. In women with PCOS, metformin has been found to reduce PAI-1 activity and levels of hsCRP to a