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impact QoL due to long-term dependence on medical care and having only a passive role in one’s self-care. SSA can be administered as an intra-muscular injection(s) or as a deep subcutaneous injection(s). Because lanreotide autogel is supplied in prefilled
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Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France
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Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France
Inserm UMR1185, Le Kremlin Bicetre, Paris, France
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Inserm UMR1185, Le Kremlin Bicetre, Paris, France
Paris-Saclay University, Paris, France
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(recombinant human chorionic gonadotrophin) treatment, and previous intra-muscular testosterone administration. Testicular volume based on ultrasound was calculated by the ellipsoid formula = width × height 2 × π/6. Parental consent for the treatment had
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Université Pierre et Marie Curie, Sorbonne Université, Paris, France
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INSERM UMR_S933, Paris, France
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Université Pierre et Marie Curie, Sorbonne Université, Paris, France
INSERM UMR_S933, Paris, France
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precursors such as DHEA-S leading to testosterone biosynthesis via peripheral non-mutated HSD3B1 and HSD17B5 activity ( Fig. 1 ). Some patients in the literature have been treated with intra-muscular testosterone injections. The main goal of this
Universitat Oberta Catalunya (UOC), Barcelona, Spain
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Univ Autònoma de Barcelona, Cerdanyola del Vallès, Spain
Fundació Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol, Barcelona, Spain
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Univ Autònoma de Barcelona, Cerdanyola del Vallès, Spain
Fundació Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol, Barcelona, Spain
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). Experimental procedure Those with abnormal GH secretion ( n = 13, 12 males 1 female) were randomized (computer-based) in a double-blind, placebo-controlled study. They received identical subcutaneous injections of either placebo ( n = 5) or GH (Nutropin Aq
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-linked immunosorbent assay (FGF23 (C-terminal) kit, Immunotopics, Inc, San Clemente, CA, USA). The kit has sensitivity, an intra-assay coefficient of variation (CV), and an inter-assay CV of 30 RU/mL, 5 and 7.3%, respectively. Serum 1,25(OH)2 vitamin D was assessed by