School of Women’s & Children’s Health, Discipline of Obstetrics and Gynaecology, University of New South Wales, Sydney, Australia
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). The key ovarian factors believed responsible are the steroids, oestradiol and progesterone, and the protein hormones, inhibin A and B. However, their respective roles are not clearly understood. In a previous study (( 2 ), and ( 3 ) designated in
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Clinical Research Centre, Medical University of Bialystok, Białystok, Poland
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hormonal markers, dynamic tests, and ultrasonographic (USG) parameters, for example, antral follicle count (AFC). Markers such as the serum levels of anti-Müllerian hormone (AMH), follicle-stimulating hormone (FSH), or inhibin B are relatively good
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Imperial College London, Institute of Reproductive and Developmental Biology, London, UK
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Malmö University Hospital, Reproductive Medicine Center, Malmö, Sweden
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). Clinical chemistry measurements Biomarkers measured in human plasma/serum at the department of Clinical Chemistry, Scania University Hospital, Malmö, Sweden, included PSA, testosterone, LH, FSH, and inhibin B. The analyses were done on a Cobas 6000
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Section of Biostatistics, Department of Public Health, University of Copenhagen, Copenhagen, Denmark
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risk of azoospermia). Reproductive hormones and semen samples From a clinical database, we obtained registered daytime circulating levels of follicle-stimulating hormone (FSH), LH, total testosterone, and inhibin B as well as registered semen
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Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France
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Université Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France
Inserm UMR1185, Le Kremlin Bicetre, Paris, France
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Inserm UMR1185, Le Kremlin Bicetre, Paris, France
Paris-Saclay University, Paris, France
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cells, and perhaps, by extension, for future fertility ( 3 , 4 , 5 , 6 ). Anti-Müllerian hormone (AMH) and Inhibin B are reliable biomarkers reflecting Sertoli cells function, while testosterone is an index of Leydig cell activation. Boys with CHH
Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
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John Walton Muscular Dystrophy Research Centre, Newcastle University and Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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John Walton Muscular Dystrophy Research Centre, Newcastle University and Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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John Walton Muscular Dystrophy Research Centre, Newcastle University and Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK
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John Walton Muscular Dystrophy Research Centre, Newcastle University and Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK
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therefore clinical and biochemical markers of HPG activity including inhibin B concentrations. The initial intention was to follow the participants on two further occasions, at 1 and 2 years after that visit. However, as a result of the coronavirus disease
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Université Pierre et Marie Curie, Sorbonne Université, Paris, France
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INSERM UMR_S933, Paris, France
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Université Pierre et Marie Curie, Sorbonne Université, Paris, France
INSERM UMR_S933, Paris, France
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his written consent for the study. Morning samples for steroids, FSH, LH and inhibin B, AMH were sent to the accredited (Cofrac: www.cofrac.fr) clinical endocrinology laboratories in Saint Antoine and Cochin hospitals respectively. These
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, free testosterone, or inhibin B. There were no restrictions on the language, date of publication, or status of the study. Exclusion criteria: case reports, reviews, and animal studies were excluded. Studies that included non-thyroid cancer patients
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Pediatric Endocrinology Clinic, Department of Pediatrics, Aretaeio Hospital, Nicosia, Cyprus
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Denmark
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testosterone, inhibin B and anti-Müllerian hormone (AMH). Elevated concentrations of adrenal androgens may result in testosterone concentrations within the reference range despite low LH and FSH concentrations in CAH patients. Thus, additional markers of Leydig
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in humans, although some controversy exists ( 1 , 2 ). Through negative feedback, testosterone is the predominant regulator of LH, whereas inhibin b is the predominant regulator of FSH ( 2 ). Congenital hypogonadotropic hypogonadism (CHH) is