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Maria Stelmachowska-Banaś Department of Endocrinology, The Centre of Postgraduate Medical Education, Warsaw, Polska, Poland

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Izabella Czajka-Oraniec Department of Endocrinology, The Centre of Postgraduate Medical Education, Warsaw, Polska, Poland

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with anti-PD-1 antibodies and hypophysitis (IH) commonly related to anti-CTLA-4 therapy, are the most frequent endocrine toxicities. ICI-induced insulin-deficient diabetes mellitus (DM) and primary adrenal insufficiency (PAI), though rare, can be life

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0342
Volume/Issue:
Volume 9: Issue 10
Open access
Bliss Anderson Department of Endocrinology, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK

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Daniel L Morganstein Department of Endocrinology, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK

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lifelong hormonal replacement. Untreated endocrinopathy can be life threatening. Whilst both CTLA-4 and PD-1 inhibitors are associated most commonly with thyroid dysfunction, hypophysitis resulting in adrenal insufficiency, and insulin-dependent diabetes

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0489
Volume/Issue:
Volume 10: Issue 3
Open access
Brijesh Krishnappa Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Ravikumar Shah Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Saba Samad Memon Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Chakra Diwaker Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Anurag R Lila Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Virendra A Patil Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Nalini S Shah Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Tushar R Bandgar Department of Endocrinology, K E M Hospital and Seth G S Medical College, Mumbai, India

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Introduction Hypophysitis is the general term used to describe any form of sellar and/or suprasellar inflammation that leads to structural changes in the hypothalamic–pituitary axis and varying degrees of anterior and/or posterior pituitary

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0311
Volume/Issue:
Volume 12: Issue 2
Open access
Ruth Percik Institute of Endocrinology, Diabetes and Metabolism, Sheba Medical Centre, Ramat Gan, Israel

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Sherwin Criseno Department of Endocrinology, University Hospital Birmingham, Birmingham, UK

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Safwaan Adam Department of Endocrinology, The Christie NHS Foundation Trust, Manchester, UK

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Kate Young Royal Marsden Hospital, London, UK

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Daniel L Morganstein Department of Endocrinology, Chelsea and Westminster Hospital, London, UK
Royal Marsden Hospital, London, UK

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ADL Severe symptoms; limiting self-care ADL; hospitalization indicated Life-threatening consequences; urgent intervention indicated Death Pituitary Hypophysitis Asymptomatic or mild symptoms; clinical or diagnostic observations only

Article Type:
Review Article
Collections:
Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-22-0513
Volume/Issue:
Volume 12: Issue 5
Open access
C E Higham Department of Endocrinology, Christie Hospital NHS Foundation Trust, Manchester, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK

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A Olsson-Brown The Clatterbridge Cancer Centre, Bebbington, Wirral, UK
The University of Liverpool, Brownlow Hill, Liverpool, UK

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P Carroll Department of Endocrinology, Guy’s & St. Thomas’ NHS Foundation Trust, London, UK

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T Cooksley Department of Acute Medicine, UHSM and Christie Hospital NHS Foundation Trust, Manchester, UK

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J Larkin Skin Unit, Royal Marsden Hospital, London, UK

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P Lorigan Department of Medical Oncology, Christie Hospital NHS Foundation Trust, Manchester, UK

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D Morganstein Department of Endocrinology, Chelsea and Westminster Hospital, London, UK

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P J Trainer Department of Endocrinology, Christie Hospital NHS Foundation Trust, Manchester, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK

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the Society for Endocrinology Clinical Committee The Society for Endocrinology, Starling House, 1600 Bristol Parkway North, Bristol, UK

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by immune-mediated adverse effects particularly with combination treatment ( 3 , 4 , 5 , 6 ). Immune-mediated endocrinopathies as a consequence of treatment with checkpoint inhibitors include hypophysitis, adrenalitis, thyroiditis and diabetes

Article Type:
Other
DOI:
https://doi.org/10.1530/EC-18-0068
Volume/Issue:
Volume 7: Issue 7
Open access
Kunal Thakkar Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Swati Ramteke-Jadhav Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Rajeev Kasaliwal Department of Endocrinology, Mahatma Gandhi Medical College & Hospital, Jaipur, India

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Saba Samad Memon Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Virendra Patil Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Puja Thadani Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Nilesh Lomte Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Shilpa Sankhe Department of Radiology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Atul Goel Department of Neurosurgery, Seth G S Medical College & KEM Hospital, Mumbai, India

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Sridhar Epari Department of Pathology, Tata Memorial Centre, Mumbai, India

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Naina Goel Department of Neuropathology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Anurag Lila Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Nalini S Shah Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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Tushar Bandgar Department of Endocrinology, Seth G S Medical College & KEM Hospital, Mumbai, India

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–16%), rathke’s cleft cyst (RCC, 28–33%), lymphocytic hypophysitis (LyH, 5%), and meningioma (3–8%) ( 3 , 4 ). These lesions often have characteristic radiological appearance suggesting pre-operative diagnosis. However, besides these common lesions, certain

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0497
Volume/Issue:
Volume 9: Issue 2
Open access
Hanna Karhapää Medical Faculty, University of Helsinki, Helsinki, Finland
Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland

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Siru Mäkelä Medical Faculty, University of Helsinki, Helsinki, Finland
Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland

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Hanna Laurén Medical Faculty, University of Helsinki, Helsinki, Finland
Department of Radiology, HUS Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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Marjut Jaakkola Medical Faculty, University of Helsinki, Helsinki, Finland
Department of Radiology, HUS Medical Imaging Centre, University of Helsinki and Helsinki University Hospital, Helsinki, Finland

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Camilla Schalin-Jäntti Medical Faculty, University of Helsinki, Helsinki, Finland
Endocrinology, Abdominal Centre, University of Helsinki and HUS, Helsinki, Finland

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Micaela Hernberg Medical Faculty, University of Helsinki, Helsinki, Finland
Department of Oncology, Comprehensive Cancer Centre, Helsinki University Hospital, Helsinki, Finland

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laboratory findings to life-threatening conditions requiring immediate diagnosis and treatment ( 6 , 7 ). Endocrine AEs are the third most common AEs of ICIs including thyroiditis, hypophysitis, and autoimmune diabetes ( 8 ). The frequency of endocrine AEs

Article Type:
Research Article
Collections:
Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-21-0562
Volume/Issue:
Volume 11: Issue 2
Open access
Saroj Kumar Sahoo Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Division of Endocrinology, Mid and South Essex NHS Trust, Broomfield, UK

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Jayakrishnan C Menon Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

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Nidhi Tripathy Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

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Monalisa Nayak Department of Liver Intensive Care Unit, King’s College Hospital, London, UK

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Subhash Yadav Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India

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stimulation test, such as insulin tolerance test. The other mechanisms behind a delayed onset of AI could be secondary to reactivation of latent viral infection, post-infectious hypophysitis ( 30 , 31 ), vaccine medicated ( 32 ), or an autoimmunity ( 33 , 34

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-24-0086
Volume/Issue:
Volume 13: Issue 9
Open access
Amit Kumar Department of Medicine, Christian Medical College and Hospital, Ludhiana, Punjab, India

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Maria Ghosh Department of Biochemistry, Christian Medical College and Hospital, Ludhiana, Punjab, India

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Jubbin Jagan Jacob Department of Endocrinology, Christian Medical College and Hospital, Ludhiana, Punjab, India

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included undiagnosed hypopituitarism 5/20 (25 or 3.5% among all patient with EuVHNa) which included three patients with post-partum pituitary necrosis (Sheehan’s syndrome) and two patients with possible lymphocytic hypophysitis. We were surprised to note

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0500
Volume/Issue:
Volume 10: Issue 12
Open access
Aida Javanbakht Department of Diabetes, Endocrinology and Metabolism, Beckman Research Institute of City of Hope, Duarte, California, USA

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Massimo D’Apuzzo Department of Pathology, Beckman Research Institute of City of Hope, Duarte, California, USA

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Behnam Badie Department of Neurosurgery, Beckman Research Institute of City of Hope, Duarte, California, USA

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Behrouz Salehian Department of Diabetes, Endocrinology and Metabolism, Beckman Research Institute of City of Hope, Duarte, California, USA

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Endocrinological Investigation 2005 28 454 – 458 . ( https://doi.org/10.1007/BF03347227 ) 16075930 10.1007/BF03347227 57 Huang YY Lin SF Dunn P Wai YY Hsueh C Tsai JS . Primary pituitary lymphoma presenting as hypophysitis . Endocrine Journal 2005 52

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0338
Volume/Issue:
Volume 7: Issue 10
Open access