Nelma Veronica Marques
Nelma Veronica Marques
Neuroendocrinology Research Center, Endocrinology Section, Medical School and Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Luiz Eduardo Armondi Wildemberg
Luiz Eduardo Armondi Wildemberg
Neuroendocrinology Research Center, Endocrinology Section, Medical School and Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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Monica R Gadelha
Monica R Gadelha
Neuroendocrinology Research Center, Endocrinology Section, Medical School and Hospital Universitário Clementino Fraga Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
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≥ 126 mg/dL, glycated haemoglobin (HbA1c) ≥ 6.5% or receiving medication for hyperglycaemia. Nine patients had undergone transsphenoidal surgery before pasireotide treatment. Most patients had been treated with first-generation SRLs and/or cabergoline
Xiaolei Hu
Xiaolei Hu
Department of Endocrinology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China
Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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Fengling Chen
Fengling Chen
Department of Endocrinology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
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variability and metabolic control ( 1 ), and mainly with insulin resistance/hyperglycaemia ( 6 , 10 , 14 , 15 , 16 ) or hypoglycaemia ( 6 , 7 , 8 , 10 , 17 , 18 ). Therefore, we named this condition exogenous insulin antibody syndrome (EIAS). Recently
Ivar Følling
Ivar Følling
Department of Endocrinology, Akershus University Hospital, Lørenskog, Norway
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway
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Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway
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Anna B Wennerstrøm
Anna B Wennerstrøm
Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway
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Tor J Eide
Tor J Eide
Division of Laboratory Medicine, Department of Pathology, Oslo University Hospital, Oslo, Norway
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Hilde Loge Nilsen
Hilde Loge Nilsen
Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway
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Department of Clinical Molecular Biology, University of Oslo and Akershus University Hospital, Lørenskog, Norway
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production of insulin and related molecules could cause or contribute to the two kinds of glucose imbalances seen in patients with phaeochromocytoma. First, hyperglycaemia is common, occurring in 21–37% of the patients and is probably caused by the secreted
Yuan Zhou
Yuan Zhou
Department of Endocrinology and Metabology, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
Laboratory of Endocrinology, Medical Research Center, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
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Laboratory of Endocrinology, Medical Research Center, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
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ShengNan Wang
ShengNan Wang
Department of Endocrinology and Metabology, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
Laboratory of Endocrinology, Medical Research Center, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
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Laboratory of Endocrinology, Medical Research Center, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
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Jing Wu
Jing Wu
Department of Endocrinology and Metabology, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
Laboratory of Endocrinology, Medical Research Center, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
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Laboratory of Endocrinology, Medical Research Center, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
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JianJun Dong
JianJun Dong
Department of Endocrinology, Qilu Hospital of Shandong University, Ji-nan, China
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Lin Liao
Lin Liao
Department of Endocrinology and Metabology, The First Affiliated Hospital of Shandong First Medical University, Ji-nan, China
Department of Endocrinology and Metabology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Ji-nan, China
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Department of Endocrinology and Metabology, Shandong Provincial Qianfoshan Hospital, Cheeloo College of Medicine, Shandong University, Ji-nan, China
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, mild fasting hyperglycaemia named MODY2 ( 9 ). Clinical features of MODY2 include a non-progressive slight increase in glycated hemoglobin (HbA1c), usually between 5.6% and 7.6%, and mildly raised fasting glucose (usually between 5.4–8.3 mmol/L) ( 10
Punith Kempegowda
Punith Kempegowda
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Eka Melson
Eka Melson
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Agnes Johnson
Agnes Johnson
College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
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Lucy Wallett
Lucy Wallett
College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
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Lucretia Thomas
Lucretia Thomas
College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
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Dengyi Zhou
Dengyi Zhou
College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
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Catherine Holmes
Catherine Holmes
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Agata Juszczak
Agata Juszczak
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Mohammed Ali Karamat
Mohammed Ali Karamat
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Sandip Ghosh
Sandip Ghosh
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Wasim Hanif
Wasim Hanif
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Parth Narendran
Parth Narendran
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK
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Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK
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Srikanth Bellary
Srikanth Bellary
University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
School of Life and Health Sciences, Aston University, Birmingham, UK
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School of Life and Health Sciences, Aston University, Birmingham, UK
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absolute risk of death in the lower age groups was small ( 2 ). Diabetic ketoacidosis (DKA) is an acute complication of diabetes characterised by hyperglycaemia, metabolic acidosis and ketosis ( 3 , 4 ). The management of DKA includes aggressive re
Marko Stojanovic
Marko Stojanovic
Neuroendocrinology Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Belgrade, Serbia
University of Belgrade, Medical Faculty, Belgrade, Serbia
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University of Belgrade, Medical Faculty, Belgrade, Serbia
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Zida Wu
Zida Wu
Department of Medicine for Endocrinology, Diabetes and Nutritional Medicine, Charité Universitätsmedizin, Campus Mitte, Berlin, Germany
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Craig E Stiles
Craig E Stiles
Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
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Dragana Miljic
Dragana Miljic
Neuroendocrinology Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Belgrade, Serbia
University of Belgrade, Medical Faculty, Belgrade, Serbia
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University of Belgrade, Medical Faculty, Belgrade, Serbia
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Ivan Soldatovic
Ivan Soldatovic
University of Belgrade, Medical Faculty, Belgrade, Serbia
Insitute of Medical Statistics and Informatics, Belgrade, Serbia
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Insitute of Medical Statistics and Informatics, Belgrade, Serbia
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Sandra Pekic
Sandra Pekic
Neuroendocrinology Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Belgrade, Serbia
University of Belgrade, Medical Faculty, Belgrade, Serbia
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University of Belgrade, Medical Faculty, Belgrade, Serbia
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Mirjana Doknic
Mirjana Doknic
Neuroendocrinology Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Belgrade, Serbia
University of Belgrade, Medical Faculty, Belgrade, Serbia
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University of Belgrade, Medical Faculty, Belgrade, Serbia
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Milan Petakov
Milan Petakov
Neuroendocrinology Department, Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Centre of Serbia, Belgrade, Serbia
University of Belgrade, Medical Faculty, Belgrade, Serbia
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University of Belgrade, Medical Faculty, Belgrade, Serbia
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Vera Popovic
Vera Popovic
University of Belgrade, Medical Faculty, Belgrade, Serbia
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Christian Strasburger
Christian Strasburger
Department of Medicine for Endocrinology, Diabetes and Nutritional Medicine, Charité Universitätsmedizin, Campus Mitte, Berlin, Germany
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Márta Korbonits
Márta Korbonits
Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
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ITT) or hyperglycaemia (induced by OGTT). Despite apparent AIP and GH co-localization in somatotroph secretory vesicles upon electromicroscopy and double fluorescence immunostaining ( 3) , results of this study demonstrated that serum AIP
Pernille H Hellmann
Pernille H Hellmann
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Jonatan I Bagger
Jonatan I Bagger
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Katrine R Carlander
Katrine R Carlander
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Katrine B Hansen
Katrine B Hansen
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Julie L Forman
Julie L Forman
Section of Biostatistics, Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Joachim Størling
Joachim Størling
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Elizaveta Chabanova
Elizaveta Chabanova
Department of Radiology, Herlev Hospital, University of Copenhagen, Herlev, Denmark
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Jens Holst
Jens Holst
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Tina Vilsbøll
Tina Vilsbøll
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Filip K Knop
Filip K Knop
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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that expression of 2% of our genome is regulated by glucocorticoids ( 5 ). Prednisolone is known to induce insulin resistance, increased hepatic glucose production, hyperglycaemia and secondary diabetes. Even lean, healthy individuals can experience
Magnus F G Grøndahl
Magnus F G Grøndahl
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Jonatan I Bagger
Jonatan I Bagger
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Malte P Suppli
Malte P Suppli
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Gerrit Van Hall
Gerrit Van Hall
Department of Clinical Biochemistry, Clinical Metabolomics Core Facility, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Nicolai J W Albrechtsen
Nicolai J W Albrechtsen
Department of Clinical Biochemistry, University Hospital Copenhagen, Bispebjerg, Copenhagen, Denmark
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Jens J Holst
Jens J Holst
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Tina Vilsbøll
Tina Vilsbøll
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
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Mikkel B Christensen
Mikkel B Christensen
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Pharmacology, Copenhagen University Hospital – Bispebjerg and Frederiksberg, Copenhagen, Denmark
Copenhagen Center for Translational Research, Copenhagen University Hospital – Bispebjerg and Frederiksberg, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Pharmacology, Copenhagen University Hospital – Bispebjerg and Frederiksberg, Copenhagen, Denmark
Copenhagen Center for Translational Research, Copenhagen University Hospital – Bispebjerg and Frederiksberg, University of Copenhagen, Copenhagen, Denmark
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Asger B Lund
Asger B Lund
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
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Filip K Knop
Filip K Knop
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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of glucagon, hyperglucagonaemia, are observed in several obesity-related diseases including type 2 diabetes and non-alcoholic fatty liver disease where it contributes to an increased risk of hyperglycaemia ( 3 , 4 , 5 , 6 , 7 , 8 , 9 ). The
Helga Schultz
Helga Schultz
Department of Cardiology, Nephrology and Endocrinology, Nordsjællands Hospital, Hillerød, Denmark
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Svend Aage Engelholm
Svend Aage Engelholm
Department of Radiation Oncology, Rigshospitalet, Copenhagen, Denmark
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Eva Harder
Eva Harder
Department of Oncology and Palliation, Nordsjællands Hospital, Hillerød, Denmark
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Ulrik Pedersen-Bjergaard
Ulrik Pedersen-Bjergaard
Department of Cardiology, Nephrology and Endocrinology, Nordsjællands Hospital, Hillerød, Denmark
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Peter Lommer Kristensen
Peter Lommer Kristensen
Department of Cardiology, Nephrology and Endocrinology, Nordsjællands Hospital, Hillerød, Denmark
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plasma glucose level ≥11.1 mmol/L accompanied by classical symptoms of hyperglycaemia). The intensity of plasma glucose measurements is not reported in the paper ( 14 ). The higher incidence of insulin-treated DM in our cohort may be explained by the
Lili Liu
Lili Liu
Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Zhuo Shao
Zhuo Shao
Department of General Surgery, Changhai Hospital, The Second Military Medical University, Shanghai, Shanghai, China
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Ying Xia
Ying Xia
Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Jiabi Qin
Jiabi Qin
Department of Epidemiology & Health Statistics, Xiangya School of Public Health, Central South University, Changsha, Hunan, China
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Yang Xiao
Yang Xiao
Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Zhiguang Zhou
Zhiguang Zhou
Department of Metabolism & Endocrinology, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Key Laboratory of Diabetes Immunology, Central South University, Ministry of Education, National Clinical Research Center for Metabolic Diseases, Changsha, Hunan, China
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Zubing Mei
Zubing Mei
Department of Anorectal Surgery, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China
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, the occurrence rate of severe hypoglycaemic events, gastrointestinal side effects from the baseline to the end of treatments and hyperglycaemia with ketosis. Statistical analysis and assessment of study quality and publication bias The pooled
