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implantation of estrogen pellet and/or high-fat diet to mimic sustained estrogen stimulation and insulin resistance. The present study unraveled alterations in endometrial transcriptome profile and associated molecular pathways, which might disturb the
Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China
Department of Ultrasound, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China
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Guangdong Provincial Key Laboratory of Diabetology, Guangzhou, China
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in various tissues, including the kidney, after exposure to a high-fat diet (HFD) ( 19 ). Nevertheless, the role of SIRT1 in the protective effects of liraglutide on kidney disease induced by HFD has not yet been evaluated. Herein, we used HFD
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regulatory protein (StAR) ( 20 ). In this study, global chemerin knockout (chemerin (−/−)) mice were generated to demonstrate the roles of chemerin in regulating blood glucose and blood lipid of mice under diet (high-fat (HFD) and normal diet) and exercise
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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fasting insulin levels and HOMA-IR in Chinese subjects ( 11 ). Induction of adipose tissue fibrosis by overexpression of HIF1α led to exacerbated adipose inflammation and aggravated glucose intolerance in mice fed with a high-fat diet (HFD) ( 7 ). On the
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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the fibroblast growth factor superfamily, has attracted increasing attention in recent years for its role in regulating glucose and lipid metabolism. During the consumption of a ketogenic diet or a high-fat diet, FGF21-knockout mice develop more
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School of Science and Health, Western Sydney University, Campbelltown, New South Wales, Australia
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The Florey Institute of Neuroscience and Mental Health, Parkville, Melbourne, Victoria, Australia
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Australian Institute for Musculoskeletal Science (AIMSS), College of Health and Biomedicine, Victoria University, Melbourne, Victoria, Australia
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School of Environment and Sciences, Griffith University, Nathan, Queensland, Australia
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Centre (Canning Vale, Western Australia). Sprague–Dawley rats were selected due to their ability to gain weight on a high-fat diet (HFD). This strain of rat also shows a diverse response in weight gain following consumption of a HFD with some Sprague
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days till 6 months (after puberty) of age: a conventional moderate hay-based diet (CONV) supplemented by milk replacer during the first 8 weeks of life (provided in a suckling bucket) or a high starch, high-fat diet (HCHF), consisting of a liquid mix of
Pritzker School of Medicine, Chicago, Illinois, USA
University of Chicago, Chicago, Illinois, USA
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Committee on Molecular Pathogenesis and Molecular Medicine, Chicago, Illinois, USA
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University of Chicago, Chicago, Illinois, USA
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primarily by chronic caloric imbalance arising from increased physical inactivity and energy intake. Increasing global consumption of a ‘Western’ diet consisting of red and processed meats, refined grains, high-fat dairy products and sugary beverages results
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‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
‘Research of Age and Age-Associated Conditions’ Department, Laboratory of Bioinformatics, The ‘Russian Clinical Research Center for Gerontology’, ‘Chronic Noncommunicable Diseases Primary Prevention in the Healthcare System’ Department, Moscow Institute of Physics and Technology, National Research Centre for Preventive Medicine, National Research Centre for Preventive Medicine, Building 10, Petroverigskiy Lane, Moscow RF 101000, Russian Federation
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fat and rich in plant polysaccharides (9) , as well as switching from a high-fat diet to a diet with a low glycemic index, caused some substantial changes in the GM on the following day (10) . Despite most of the studies were descriptive, some
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Introduction Obesity, non-alcoholic fatty liver disease (NAFLD), and type 2 diabetes mellitus (T2DM) are thought to be caused by the Western, high-fat diet (HFD) ( 1 ). These diseases are associated with various gastrointestinal (GI) motility