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Sherwin Criseno Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
School of Nursing and Midwifery, Institute of Clinical Sciences, University of Birmingham, UK

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Helena Gleeson Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

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Andrew A Toogood Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

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Neil Gittoes Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

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Anne Topping School of Nursing and Midwifery, Institute of Clinical Sciences, University of Birmingham, UK

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Niki Karavitaki Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
Department of Endocrinology, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

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Introduction Growth hormone deficiency (GHD) is a clinical condition that can present in childhood or adult life. Adult-onset GHD is usually caused by a pituitary tumour and/or its treatments (surgery, radiotherapy) ( 1 ). Although the true

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-23-0533
Volume/Issue:
Volume 13: Issue 5
Open access
Jin Kyu Oh Department of Urology, College of Medicine, Gachon University, Incheon, Republic of Korea

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Young Jae Im Department of Urology, College of Medicine, Seoul National University, Seoul, Republic of Korea

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Kwanjin Park Department of Urology, College of Medicine, Seoul National University, Seoul, Republic of Korea

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Jae-Seung Paick Department of Urology, College of Medicine, Seoul National University, Seoul, Republic of Korea

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, testosterone enanthate (Savient Pharmaceuticals, East Brunswick, NJ, USA) was administered intramuscularly at 0.4 mg/kg/week. GH (recombinant human growth hormone bulk solution, LG Life Sciences, Korea) treatments were administered subcutaneously on alternate

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0200
Volume/Issue:
Volume 7: Issue 11
Open access
Urszula Smyczyńska Department of Automatics and Biomedical Engineering, AGH University of Science and Technology, Krakow, Poland

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Joanna Smyczyńska Department of Endocrinology and Metabolic Diseases, Polish Mother’s Memorial Hospital – Research Institute, Lodz, Poland

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Maciej Hilczer Department of Endocrinology and Metabolic Diseases, Polish Mother’s Memorial Hospital – Research Institute, Lodz, Poland
Department of Paediatric Endocrinology, Medical University of Lodz, Lodz, Poland

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Renata Stawerska Department of Endocrinology and Metabolic Diseases, Polish Mother’s Memorial Hospital – Research Institute, Lodz, Poland

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Ryszard Tadeusiewicz Department of Automatics and Biomedical Engineering, AGH University of Science and Technology, Krakow, Poland

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Andrzej Lewiński Department of Endocrinology and Metabolic Diseases, Polish Mother’s Memorial Hospital – Research Institute, Lodz, Poland
Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, Lodz, Poland

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Elias and coworkers ( 37 ). Still, application of models in the field of GH treatment response prediction requires some caution due to usage of various methods of hormonal assessment and differences in growth between populations. Certainly, any model

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0277
Volume/Issue:
Volume 7: Issue 1
Open access
Alicia Romano Department of Pediatrics, New York Medical College, Valhalla, New York, USA

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Juan Pablo Kaski Centre for Inherited Cardiovascular Diseases, Great Ormond Street Hospital & UCL Institute of Cardiovascular Science, London, UK

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Jovanna Dahlgren Department of Paediatrics, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden

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Nicky Kelepouris US Medical Affairs, Novo Nordisk Inc., Plainsboro, New Jersey, USA

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Alberto Pietropoli Global Medical Affairs, Novo Nordisk Health Care AG, Zurich, Switzerland

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Tilman R Rohrer Department of Pediatric Endocrinology, University Children’s Hospital, Saarland University Medical Center, Homburg, Germany

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Michel Polak Paediatric Endocrinology, Diabetology and Gynaecology Department, Hôpital Universitaire Necker Enfants-Malades, AP-HP, Université de Paris, Imagine Institute, Paris, France

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stenosis (PVS; prevalence 50–60%), hypertrophic cardiomyopathy (HCM; 20%) and atrial septal defects (6–10%) ( 1 ). Growth hormone (GH) treatment in patients with NS improves height velocity, height standard deviation score (SDS) and adult height, with a

Article Type:
Research Article
Collections:
Cardiovascular
DOI:
https://doi.org/10.1530/EC-21-0549
Volume/Issue:
Volume 11: Issue 1
Open access
Alessandro Ciresi Section of Endocrinology, Biomedical Department of Internal and Specialist Medicine (DIBIMIS), University of Palermo, Palermo, Italy

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Stefano Radellini Section of Endocrinology, Biomedical Department of Internal and Specialist Medicine (DIBIMIS), University of Palermo, Palermo, Italy

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Valentina Guarnotta Section of Endocrinology, Biomedical Department of Internal and Specialist Medicine (DIBIMIS), University of Palermo, Palermo, Italy

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Maria Grazia Mineo Section of Endocrinology, Biomedical Department of Internal and Specialist Medicine (DIBIMIS), University of Palermo, Palermo, Italy

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Carla Giordano Section of Endocrinology, Biomedical Department of Internal and Specialist Medicine (DIBIMIS), University of Palermo, Palermo, Italy

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– 6296 . ( https://doi.org/10.1210/jc.2004-0644 ) 10.1210/jc.2004-0644 11 Span JP Pieters GF Sweep CG Hermus AR Smals AG . Gender difference in insulin-like growth factor I response to growth hormone (GH) treatment in GH-deficient adults

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0135
Volume/Issue:
Volume 7: Issue 7
Open access
Ping Li Department of Endocrinology, Beijing Shijitan Hospital, Capital Medical University, Beijing, China

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Fei Cheng Department of Endocrinology, Beijing Shijitan Hospital, Capital Medical University, Beijing, China

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Lei Xiu Department of Endocrinology, Beijing Shijitan Hospital, Capital Medical University, Beijing, China

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hormone, with a sequence identical to that of human growth hormone, marketed under any brand name; (4) intervention and comparison, rhGH alone vs placebo/no treatment, rhGH plus oxandrolone combination therapy vs rhGH alone therapy. We excluded

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0115
Volume/Issue:
Volume 7: Issue 4
Open access
Kennett Sprogøe Ascendis Pharma A/S, Hellerup, Denmark

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Eva Mortensen Ascendis Pharma, Inc., Palo Alto, California, USA

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David B Karpf Ascendis Pharma, Inc., Palo Alto, California, USA

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Jonathan A Leff Ascendis Pharma, Inc., Palo Alto, California, USA

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GH. The objective was to provide more convenient drug administration to ease the lives of patients with GHD, thereby potentially improving compliance and treatment outcomes. The Growth Hormone Research Society recently identified a number of

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-17-0203
Volume/Issue:
Volume 6: Issue 8
Open access
Werner F Blum University Children’s Hospital, Giessen, Germany

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Abdullah Alherbish Al Habib Medical Group, Riyadh, Saudi Arabia

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Afaf Alsagheir King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia

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Ahmed El Awwa Department of Pediatric Endocrinology & Diabetes, Hamad Medical Center, Doha, Qatar

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Walid Kaplan Tawam Hospital, Al Ain, UAE

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Ekaterina Koledova Global Medical Affairs Endocrinology, Merck KGaA, Darmstadt, Germany

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Martin O Savage William Harvey Research Institute, Barts and the London School of Medicine & Dentistry, London, UK

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Research in Paediatrics 2011 75 335 – 345 . ( https://doi.org/10.1159/000322878 ) 10.1159/000322878 21228552 3 Sprogøe K Mortensen E Karpf DB Leff JA. The rationale and design of TransCon Growth Hormone for the treatment of growth hormone

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0099
Volume/Issue:
Volume 7: Issue 6
Open access
Juliane Léger Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service d’Endocrinologie Diabétologie Pédiatrique, Centre de Référence des Maladies Endocriniennes de la Croissance et du développement, Paris, France
Université Paris Diderot, Sorbonne Paris Cité, Paris, France
Institut National de la Santé et de la Recherche Médicale (INSERM), Unité 1141, DHU PROTECT, Paris, France

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Anne Fjellestad-Paulsen Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service d’Endocrinologie Diabétologie Pédiatrique, Centre de Référence des Maladies Endocriniennes de la Croissance et du développement, Paris, France

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Anne Bargiacchi Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service de Psychiatrie de l’Enfant et de l’Adolescent, Centre de Référence des Maladies Endocriniennes de la Croissance et du développement, Paris, France

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Catherine Doyen Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service de Psychiatrie de l’Enfant et de l’Adolescent, Centre de Référence des Maladies Endocriniennes de la Croissance et du développement, Paris, France

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Emmanuel Ecosse Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service d’Endocrinologie Diabétologie Pédiatrique, Centre de Référence des Maladies Endocriniennes de la Croissance et du développement, Paris, France

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Jean-Claude Carel Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service d’Endocrinologie Diabétologie Pédiatrique, Centre de Référence des Maladies Endocriniennes de la Croissance et du développement, Paris, France
Université Paris Diderot, Sorbonne Paris Cité, Paris, France
Institut National de la Santé et de la Recherche Médicale (INSERM), Unité 1141, DHU PROTECT, Paris, France

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Marie-France Le Heuzey Assistance Publique-Hôpitaux de Paris, Hôpital Robert Debré, Service de Psychiatrie de l’Enfant et de l’Adolescent, Centre de Référence des Maladies Endocriniennes de la Croissance et du développement, Paris, France

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-controlled study . Journal of Clinical Endocrinology and Metabolism 2010 95 4889 – 4897 . ( doi:10.1210/jc.2010-0493 ) 10.1210/jc.2010-0493 22 Leger J Garel C Fjellestad-Paulsen A Hassan M Czernichow P. Human growth hormone treatment

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0200
Volume/Issue:
Volume 6: Issue 8
Open access
Ichelle Maa van Roessel Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center Utrecht, AB Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands

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Boudewijn Bakker Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center Utrecht, AB Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands

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Hanneke M van Santen Department of Pediatric Endocrinology, Wilhelmina Children's Hospital, University Medical Center Utrecht, AB Utrecht, The Netherlands
Princess Máxima Center for Pediatric Oncology, AB Utrecht, The Netherlands

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Wassim Chemaitilly Division of Pediatric Endocrinology, UPMC Children’s Hospitalof Pittsburgh, Pittsburgh, Pennsylvania, USA

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Introduction Endocrine disorders affect up to 60% of childhood cancer survivors (CCS) ( 1 ). Cancer, brain tumors and their treatments have been associated with a higher risk of deficiencies in growth hormone (GH), thyroid hormone and sex

Article Type:
Review Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0382
Volume/Issue:
Volume 12: Issue 1
Open access