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such patients ( 6 ). Because receiving RAI may threaten male patients’ testicular function and even affect fertility, it is crucial to understand the impact of RAI on gonadal function in this population. Although previous domestic and foreign studies
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Hematology Department, Fundeni Hospital, Bucharest, Romania
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Endocrine Department, Elias Hospital, Bucharest, Romania
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following HSCT results in a spectrum of gonadal function with varied clinical outcomes ( 5 ). Ovarian failure after HSCT has been observed in 65–84% of transplant recipients ( 5 , 12 , 13 , 14 ). In patients performing HSCT for hematological malignancies
Department of Nuclear Medicine, CHU de Bordeaux, Pessac, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France
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INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France
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Department of Nuclear Medicine, CHU de Bordeaux, Pessac, France
INRA, Nutrition et Neurobiologie Intégrée, UMR1286, Bordeaux, France
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differentiation, and for the maintenance of some very specific cell functions such as photo-transduction. Vitamin A deficiency is a marker of malnutrition that correlates with infection and mortality in children and possibly in childbearing women. Vitamin A is
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Department of Clinical Medicine, Faculty of Health and Clinical Sciences, Copenhagen University, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Clinical Sciences, Copenhagen University, Copenhagen, Denmark
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effect of pituitary surgery on pituitary function ( Table 5 ) evaluated 7.1 ± 3.1 months post-surgery was found, with endocrine recovery rates exceeding the number of new insufficiencies. Recovery rates for the adrenal, thyroid and gonadal axes were 8
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Division of Haematology-Oncology and Stem Cell Transplantation, Children’s Hospital, University of Helsinki, Helsinki University Central Hospital, Helsinki, Finland
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Edinburgh Royal Hospital for Sick Children, Edinburgh, UK
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– 223 . ( https://doi.org/10.1097/MED.0000000000000156 ) 5 Anderson RA Mitchell RT Kelsey TW Spears N Telfer EE Wallace WH . Cancer treatment and gonadal function: experimental and established strategies for fertility preservation in children and
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Introduction The brain–pituitary–gonad axis is a signaling cascade of hormones and their receptors that regulates reproduction in all jawed vertebrates. A milieu of stimulatory and inhibitory neuropeptides throughout different nuclei of the
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Université Pierre et Marie Curie, Sorbonne Université, Paris, France
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INSERM UMR_S933, Paris, France
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Université Pierre et Marie Curie, Sorbonne Université, Paris, France
INSERM UMR_S933, Paris, France
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Leboeuf G Van Vliet G Simard J. A novel A10E homozygous mutation in the HSD3B2 gene causing severe salt-wasting 3β-hydroxysteroid dehydrogenase deficiency in 46,XX and 46,XY French-Canadians: evaluation of gonadal function after puberty . Journal of
International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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Pediatric Endocrinology Clinic, Department of Pediatrics, Aretaeio Hospital, Nicosia, Cyprus
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
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International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Denmark
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; however, adult patients with CAH often experience inadequate treatment with health sequelae including an impaired gonadal function ( 3 ). One of the most important testicular complications in male patients with CAH is the development of testicular
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Introduction Over the past decades, research attention has been increasingly paid to the examination of the neurobiological component of sexual function. Female sexual desire and arousal have been shown to have a heritable component of
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Introduction Kisspeptin is an upstream regulator of the reproductive axis (hypothalamic–pituitary–gonadal, HPG axis) ( 1 ). Kisspeptin interacts with its receptor, KissR (G protein-coupled receptor 54, GPR54), resulting in the release of the