Filter

Refine by collections

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 1 - 10 of 83 items for :

  • glucagon-like peptide-1 (GLP-1) x
Clear All
Justyna Modrzynska Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Justyna Modrzynska in
Google Scholar
PubMed Close
,
Christine F Klein Department of Cardiology, Herlev Gentofte Hospital, Herlev, Denmark

Search for other papers by Christine F Klein in
Google Scholar
PubMed Close
,
Kasper Iversen Department of Clinical Medicine, Herlev Gentofte Hospital, Herlev, Denmark

Search for other papers by Kasper Iversen in
Google Scholar
PubMed Close
,
Henning Bundgaard Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Henning Bundgaard in
Google Scholar
PubMed Close
,
Bolette Hartmann Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Bolette Hartmann in
Google Scholar
PubMed Close
,
Maike Mose Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

Search for other papers by Maike Mose in
Google Scholar
PubMed Close
,
Nikolaj Rittig Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark

Search for other papers by Nikolaj Rittig in
Google Scholar
PubMed Close
,
Niels Møller Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark

Search for other papers by Niels Møller in
Google Scholar
PubMed Close
,
Jens J Holst Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Jens J Holst in
Google Scholar
PubMed Close
, and
Nicolai J Wewer Albrechtsen Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Nicolai J Wewer Albrechtsen in
Google Scholar
PubMed Close

Introduction Glucagon and glucagon-like peptide-1 (GLP-1) are processed from the same precursor, proglucagon ( Fig. 1 ), and have opposite effects on glucose homeostasis ( 1 , 2 , 3 ). In the intestine, proglucagon is cleaved by prohormone

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0590
Volume/Issue:
Volume 10: Issue 2
Open access
Nicolai J Wewer Albrechtsen NNF Center for Basic Metabolic Research and Department of Biomedical Sciences, Department of Science, Faculty of Health Science, University of Copenhagen, Blegdamsvej 3B, 12.2, DK‐2200 Copenhagen N, Denmark

Search for other papers by Nicolai J Wewer Albrechtsen in
Google Scholar
PubMed Close
,
Monika J Bak NNF Center for Basic Metabolic Research and Department of Biomedical Sciences, Department of Science, Faculty of Health Science, University of Copenhagen, Blegdamsvej 3B, 12.2, DK‐2200 Copenhagen N, Denmark
NNF Center for Basic Metabolic Research and Department of Biomedical Sciences, Department of Science, Faculty of Health Science, University of Copenhagen, Blegdamsvej 3B, 12.2, DK‐2200 Copenhagen N, Denmark

Search for other papers by Monika J Bak in
Google Scholar
PubMed Close
,
Bolette Hartmann NNF Center for Basic Metabolic Research and Department of Biomedical Sciences, Department of Science, Faculty of Health Science, University of Copenhagen, Blegdamsvej 3B, 12.2, DK‐2200 Copenhagen N, Denmark

Search for other papers by Bolette Hartmann in
Google Scholar
PubMed Close
,
Louise Wulff Christensen NNF Center for Basic Metabolic Research and Department of Biomedical Sciences, Department of Science, Faculty of Health Science, University of Copenhagen, Blegdamsvej 3B, 12.2, DK‐2200 Copenhagen N, Denmark

Search for other papers by Louise Wulff Christensen in
Google Scholar
PubMed Close
,
Rune E Kuhre NNF Center for Basic Metabolic Research and Department of Biomedical Sciences, Department of Science, Faculty of Health Science, University of Copenhagen, Blegdamsvej 3B, 12.2, DK‐2200 Copenhagen N, Denmark

Search for other papers by Rune E Kuhre in
Google Scholar
PubMed Close
,
Carolyn F Deacon NNF Center for Basic Metabolic Research and Department of Biomedical Sciences, Department of Science, Faculty of Health Science, University of Copenhagen, Blegdamsvej 3B, 12.2, DK‐2200 Copenhagen N, Denmark

Search for other papers by Carolyn F Deacon in
Google Scholar
PubMed Close
, and
Jens J Holst NNF Center for Basic Metabolic Research and Department of Biomedical Sciences, Department of Science, Faculty of Health Science, University of Copenhagen, Blegdamsvej 3B, 12.2, DK‐2200 Copenhagen N, Denmark

Search for other papers by Jens J Holst in
Google Scholar
PubMed Close

Introduction Glucagon-like peptide 1 (GLP-1) and glucagon arise from differential processing of the glucagon precursor, proglucagon (PG) (1) . Both peptides are important for normal glucose homeostasis, which focused interest on their potential

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-14-0126
Volume/Issue:
Volume 4: Issue 1
Open access
Jeppe Skov Department of Endocrinology and Internal Medicine, Novo Nordisk A/S, NNF center for Basic Metabolic Research, Department of Clinical Biochemistry, Department of Clinical Physiology and Molecular Imaging, Department of Clinical Medicine, Aarhus University Hospital, Norrebrogade 44, DK-8000 Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Novo Nordisk A/S, NNF center for Basic Metabolic Research, Department of Clinical Biochemistry, Department of Clinical Physiology and Molecular Imaging, Department of Clinical Medicine, Aarhus University Hospital, Norrebrogade 44, DK-8000 Aarhus, Denmark

Search for other papers by Jeppe Skov in
Google Scholar
PubMed Close
,
Jens Juul Holst Department of Endocrinology and Internal Medicine, Novo Nordisk A/S, NNF center for Basic Metabolic Research, Department of Clinical Biochemistry, Department of Clinical Physiology and Molecular Imaging, Department of Clinical Medicine, Aarhus University Hospital, Norrebrogade 44, DK-8000 Aarhus, Denmark

Search for other papers by Jens Juul Holst in
Google Scholar
PubMed Close
,
Jens Peter Gøtze Department of Endocrinology and Internal Medicine, Novo Nordisk A/S, NNF center for Basic Metabolic Research, Department of Clinical Biochemistry, Department of Clinical Physiology and Molecular Imaging, Department of Clinical Medicine, Aarhus University Hospital, Norrebrogade 44, DK-8000 Aarhus, Denmark

Search for other papers by Jens Peter Gøtze in
Google Scholar
PubMed Close
,
Jørgen Frøkiær Department of Endocrinology and Internal Medicine, Novo Nordisk A/S, NNF center for Basic Metabolic Research, Department of Clinical Biochemistry, Department of Clinical Physiology and Molecular Imaging, Department of Clinical Medicine, Aarhus University Hospital, Norrebrogade 44, DK-8000 Aarhus, Denmark
Department of Endocrinology and Internal Medicine, Novo Nordisk A/S, NNF center for Basic Metabolic Research, Department of Clinical Biochemistry, Department of Clinical Physiology and Molecular Imaging, Department of Clinical Medicine, Aarhus University Hospital, Norrebrogade 44, DK-8000 Aarhus, Denmark

Search for other papers by Jørgen Frøkiær in
Google Scholar
PubMed Close
, and
Jens Sandahl Christiansen Department of Endocrinology and Internal Medicine, Novo Nordisk A/S, NNF center for Basic Metabolic Research, Department of Clinical Biochemistry, Department of Clinical Physiology and Molecular Imaging, Department of Clinical Medicine, Aarhus University Hospital, Norrebrogade 44, DK-8000 Aarhus, Denmark

Search for other papers by Jens Sandahl Christiansen in
Google Scholar
PubMed Close

Introduction Glucagon-like peptide-1 (GLP1) is a gut-derived incretin hormone with multiple actions in addition to control of glucose homeostasis (1) . Synthetic GLP1 receptor (GLP1R) agonists lower blood pressure in patients with type 2 diabetes

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-13-0087
Volume/Issue:
Volume 3: Issue 1
Open access
L Ahlkvist
Search for other papers by L Ahlkvist in
Google Scholar
PubMed Close
,
K Brown Department of Clinical Sciences, GlaxoSmithKline, Biomedical Center, C11, Lund University, SE 22184 Lund, Sweden

Search for other papers by K Brown in
Google Scholar
PubMed Close
, and
B Ahrén
Search for other papers by B Ahrén in
Google Scholar
PubMed Close

experiments that the incretin effect, i.e., the augmented insulin secretion seen after oral vs i.v. glucose, is increased in insulin-resistant mice (3) and that the β-cell responsiveness to intravenous glucagon-like peptide-1 (GLP1) is augmented (3, 4

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-12-0079
Volume/Issue:
Volume 2: Issue 2
Open access
Dorte Glintborg Department of Endocrinology and Metabolism, Odense University Hospital, Odense C, Denmark

Search for other papers by Dorte Glintborg in
Google Scholar
PubMed Close
,
Hanne Mumm Department of Endocrinology and Metabolism, Odense University Hospital, Odense C, Denmark

Search for other papers by Hanne Mumm in
Google Scholar
PubMed Close
,
Jens Juul Holst Department of Biomedical Sciences and NNF Centre for Basic Metabolic Research, The Panum Institute, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Jens Juul Holst in
Google Scholar
PubMed Close
, and
Marianne Andersen Department of Endocrinology and Metabolism, Odense University Hospital, Odense C, Denmark

Search for other papers by Marianne Andersen in
Google Scholar
PubMed Close

). Incretin hormones are released after meal ingestion and account for up to 70% of postprandial insulin secretion ( 3 ). Glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide are the most important incretin hormones. GLP-1 secretion is impaired

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0034
Volume/Issue:
Volume 6: Issue 4
Open access
Charlotte Janus Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Danish Diabetes Academy, Odense University Hospital, Odense, Denmark

Search for other papers by Charlotte Janus in
Google Scholar
PubMed Close
,
Dorte Vistisen Steno Diabetes Center Copenhagen, Gentofte, Denmark

Search for other papers by Dorte Vistisen in
Google Scholar
PubMed Close
,
Hanan Amadid Steno Diabetes Center Copenhagen, Gentofte, Denmark
Department of Public Health, Research Unit of Epidemiology, Aarhus University, Aarhus, Denmark

Search for other papers by Hanan Amadid in
Google Scholar
PubMed Close
,
Daniel R Witte Danish Diabetes Academy, Odense University Hospital, Odense, Denmark
Department of Public Health, Research Unit of Epidemiology, Aarhus University, Aarhus, Denmark
Steno Diabetes Center Aarhus, Aarhus, Denmark

Search for other papers by Daniel R Witte in
Google Scholar
PubMed Close
,
Torsten Lauritzen Department of Public Health, Research Unit of Epidemiology, Aarhus University, Aarhus, Denmark

Search for other papers by Torsten Lauritzen in
Google Scholar
PubMed Close
,
Søren Brage MRC Epidemiology Unit, University of Cambridge, Cambridge, UK

Search for other papers by Søren Brage in
Google Scholar
PubMed Close
,
Anne-Louise Bjerregaard Department of Public Health, Research Unit of Epidemiology, Aarhus University, Aarhus, Denmark

Search for other papers by Anne-Louise Bjerregaard in
Google Scholar
PubMed Close
,
Torben Hansen Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Torben Hansen in
Google Scholar
PubMed Close
,
Jens J Holst Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Jens J Holst in
Google Scholar
PubMed Close
,
Marit E Jørgensen Steno Diabetes Center Copenhagen, Gentofte, Denmark
National Institute of Public Health, University of Southern Denmark, Odense, Denmark

Search for other papers by Marit E Jørgensen in
Google Scholar
PubMed Close
,
Oluf Pedersen Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Oluf Pedersen in
Google Scholar
PubMed Close
,
Kristine Færch Steno Diabetes Center Copenhagen, Gentofte, Denmark

Search for other papers by Kristine Færch in
Google Scholar
PubMed Close
, and
Signe S Torekov Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Signe S Torekov in
Google Scholar
PubMed Close

for premature mortality ( 4 ). Glucagon-like peptide-1 (GLP-1) is a peptide hormone secreted from intestinal L-cells upon meal intake ( 5 ). GLP-1 stimulates insulin secretion in a glucose-dependent manner – as part of ‘the incretin effect’ – being

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0408
Volume/Issue:
Volume 8: Issue 12
Open access
Christine Rode Andreasen Steno Diabetes Center Copenhagen, Gentofte, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

Search for other papers by Christine Rode Andreasen in
Google Scholar
PubMed Close
,
Andreas Andersen Steno Diabetes Center Copenhagen, Gentofte, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

Search for other papers by Andreas Andersen in
Google Scholar
PubMed Close
,
Filip Krag Knop Steno Diabetes Center Copenhagen, Gentofte, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Filip Krag Knop in
Google Scholar
PubMed Close
, and
Tina Vilsbøll Steno Diabetes Center Copenhagen, Gentofte, Denmark
Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Tina Vilsbøll in
Google Scholar
PubMed Close

Introduction Glucagon-like peptide 1 (GLP-1) is a gut-derived glucoregulatory hormone secreted in response to food consumption. Human GLP-1 is synthesised from the proglucagon gene and is secreted from the enteroendocrine L cells ( 1 ). Some

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-21-0130
Volume/Issue:
Volume 10: Issue 7
Open access
Giuseppe Lisco Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare, Bari, Italy

Search for other papers by Giuseppe Lisco in
Google Scholar
PubMed Close
,
Anna De Tullio Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare, Bari, Italy

Search for other papers by Anna De Tullio in
Google Scholar
PubMed Close
,
Olga Disoteo Diabetology Unit, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy

Search for other papers by Olga Disoteo in
Google Scholar
PubMed Close
,
Giuseppina Piazzolla Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare, Bari, Italy

Search for other papers by Giuseppina Piazzolla in
Google Scholar
PubMed Close
,
Edoardo Guastamacchia Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare, Bari, Italy

Search for other papers by Edoardo Guastamacchia in
Google Scholar
PubMed Close
,
Carlo Sabbà Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare, Bari, Italy

Search for other papers by Carlo Sabbà in
Google Scholar
PubMed Close
,
Vincenzo De Geronimo Unit of Endocrinology, Policlinico Morgagni CCD, Catania, Italy

Search for other papers by Vincenzo De Geronimo in
Google Scholar
PubMed Close
,
Enrico Papini Department of Endocrinology and Metabolism, Regina Apostolorum Hospital, Rome, Italy

Search for other papers by Enrico Papini in
Google Scholar
PubMed Close
, and
Vincenzo Triggiani Interdisciplinary Department of Medicine, Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, School of Medicine, University of Bari “Aldo Moro”, Piazza Giulio Cesare, Bari, Italy

Search for other papers by Vincenzo Triggiani in
Google Scholar
PubMed Close

Background Glucagon-like peptide 1 receptor agonists (GLP-1RAs) have relevant antihyperglycemic effects and provide significant improvement on diabetes-related outcomes such as overweight and obesity, cardiovascular and renal impairment, and

Article Type:
Review Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-23-0257
Volume/Issue:
Volume 12: Issue 11
Open access
Shaomin Shi Division of Nephrology, The First Affiliated Hospital of Yangtze University, Jingzhou, China

Search for other papers by Shaomin Shi in
Google Scholar
PubMed Close
,
Xinghua Chen Division of Nephrology, Renmin Hospital of Wuhan University, Wuhan, China

Search for other papers by Xinghua Chen in
Google Scholar
PubMed Close
,
Wen Yu Department of Immunology, School of Medicine, Yangtze University, Jingzhou, China

Search for other papers by Wen Yu in
Google Scholar
PubMed Close
,
Xiaolan Ke Division of Nephrology, The First Affiliated Hospital of Yangtze University, Jingzhou, China

Search for other papers by Xiaolan Ke in
Google Scholar
PubMed Close
, and
Tean Ma Division of Nephrology, The First Affiliated Hospital of Yangtze University, Jingzhou, China

Search for other papers by Tean Ma in
Google Scholar
PubMed Close

the treatment of glomerular diseases and key targets for the prevention and treatment of glomerular diseases ( 10 , 11 ). Glucagon-like peptide-1 (GLP-1) is an endogenous entero-insulinotropic hormone whose main target of action is GLP-1 receptor

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-23-0284
Volume/Issue:
Volume 12: Issue 10
Open access
Shenghe Luo College of Pharmacy, Yanbian University, Yanji, China

Search for other papers by Shenghe Luo in
Google Scholar
PubMed Close
,
Yunhui Zuo Department of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, China
Department of Cardiology, Yanbian University Hospital, Yanji, China

Search for other papers by Yunhui Zuo in
Google Scholar
PubMed Close
,
Xiaotian Cui Department of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, China

Search for other papers by Xiaotian Cui in
Google Scholar
PubMed Close
,
Meiping Zhang Department of Cardiology, Yanbian University Hospital, Yanji, China

Search for other papers by Meiping Zhang in
Google Scholar
PubMed Close
,
Honghua Jin Department of Pharmacy, Yanbian University Hospital, Yanji, China

Search for other papers by Honghua Jin in
Google Scholar
PubMed Close
, and
Lan Hong Department of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji, China

Search for other papers by Lan Hong in
Google Scholar
PubMed Close

Introduction Glucagon-like peptide 1 (GLP-1) is one of the components of incretin, which can regulate the metabolism of the body and has a wide range of pharmacological effects ( 1 , 2 ). GLP-1R agonists like as liraglutide are currently

Article Type:
Research Article
Collections:
Cardiovascular
DOI:
https://doi.org/10.1530/EC-23-0176
Volume/Issue:
Volume 12: Issue 11
Open access