Search Results

You are looking at 1 - 10 of 63 items for :

  • genome-wide association study x
Clear All
Open access

Ali Abbasi

was updated via a systematic literature search to identify Mendelian randomization studies. Next, summary data from the two largest genome-wide association studies (GWAS) for T2D or glycaemic traits (10, 11) were used to examine the effect estimates

Open access

Iben Katinka Greiber, Casper P Hagen, Alexander Siegfried Busch, Mikkel Grunnet Mieritz, Lise Aksglæde, Katharina Main, Kristian Almstrup and Anders Juul

and AMHR2 may modify age at natural menopause. PLoS ONE 2013 8 8 – 11 . 26 Perry JRB McMahon G Day FR Ring SM Nelson SM Lawlor DA. Genome-wide association study identifies common and low-frequency variants at the AMH gene locus that

Open access

Ozlem Atan Sahin, Damla Goksen, Aysel Ozpinar, Muhittin Serdar and Huseyin Onay

vitamin D insufficiency: a genome-wide association study . Lancet 2010 376 180 – 188 . ( doi:10.1016/S0140-6736(10)60588-0 ) 38 Ahn J Yu K Stolzenberg-Solomon R Simon KC McCullough ML Gallicchio L Jacobs EJ Ascherio

Open access

Marco Marino, Valentina Cirello, Valentina Gnarini, Carla Colombo, Elisa Pignatti, Livio Casarini, Chiara Diazzi, Vincenzo Rochira, Katia Cioni, Bruno Madeo, Cesare Carani, Manuela Simoni and Laura Fugazzola

studies based on rs2910164 in PTC carried out so far. To the best of our knowledge, no genome-wide association studies on PTC have focused on rs2910164, rs1862391, or rs2910202 so far. Our meta-analyses, including a total of 2416 patients and 7925 controls

Open access

Renata C Scalco, Ericka B Trarbach, Edoarda V A Albuquerque, Thais K Homma, Thais H Inoue-Lima, Mirian Y Nishi, Berenice B Mendonca and Alexander A L Jorge

) and karyotype ( 7 ). Nevertheless, there are controversies among studies and none of these factors can thoroughly explain the interindividual variation. Genome-wide association studies (GWAS) showed that polymorphisms in estrogen receptor 1 gene

Open access

Dmitry M Davydov and Malik K Nurbekov

studies showed that HbA 1c is not affected by plasma glucose instability and has a close relationship with mean or average plasma glucose (MPG) ( 3 ). However, correlations between HbA 1c and FPG are low. Twin, family, and genome-wide association studies

Open access

Piera Rizzolo, Valentina Silvestri, Virginia Valentini, Veronica Zelli, Agostino Bucalo, Ines Zanna, Simonetta Bianchi, Maria Grazia Tibiletti, Antonio Russo, Liliana Varesco, Gianluca Tedaldi, Bernardo Bonanni, Jacopo Azzollini, Siranoush Manoukian, Anna Coppa, Giuseppe Giannini, Laura Cortesi, Alessandra Viel, Marco Montagna, Paolo Peterlongo, Paolo Radice, Domenico Palli and Laura Ottini

1 rs1056836 and rs1800440 may contribute to MBC risk. Notably, loci for these two candidate genes have never emerged in any of the Genome Wide Association Studies (GWAS) on both female and male BCs as reported in the GWAS Catalog ( 33 ), thus

Open access

Katherine A Bolton, Kelly A Avery-Kiejda, Elizabeth G Holliday, John Attia, Nikola A Bowden and Rodney J Scott

be analysed on a large scale, with recent emphasis being on genome-wide association studies, which are unable to detect polymorphisms produced by variable TRs ( 49 ). High-throughput techniques, such as next-generation sequencing, are not readily

Open access

Yao Chen and Shu-ying Fang

), where it participates in energy metabolism ( 37 ). A genome-wide association study in 2007 associated the FTO gene with body mass index (BMI) and obesity ( 38 ). Obesity is a common characteristic of PCOS; more than 50% of PCOS patients are overweight

Open access

Zhen-yu Song, Qiuming Yao, Zhiyuan Zhuo, Zhe Ma and Gang Chen

clarify the association between vitamin D and PCa. Some experimental studies indicated that vitamin D might play a crucial role in the occurrence and progression of PCa. One study demonstrated mutations of vitamin D receptor gene were associated with