Filter

Refine by collections

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 1 - 10 of 255 items for :

Clear All
Masatada Watanabe Laboratory of Tissue Regeneration, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Shinagawa, Tokyo, Japan

Search for other papers by Masatada Watanabe in
Google Scholar
PubMed Close
,
Shuji Ohno Division of Research for Pharmacy Students Education, Hoshi University, Shinagawa, Tokyo, Japan

Search for other papers by Shuji Ohno in
Google Scholar
PubMed Close
, and
Hiroshi Wachi Laboratory of Tissue Regeneration, Hoshi University School of Pharmacy and Pharmaceutical Sciences, Shinagawa, Tokyo, Japan

Search for other papers by Hiroshi Wachi in
Google Scholar
PubMed Close

Introduction Sex steroids are important for the maintenance of healthy skin. Based on studies on older women, sex steroids in skin regulate the collagen content and the synthesis of hyaluronic acid ( 1 ). Estrogen-conjugated cream applied to

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-16-0099
Volume/Issue:
Volume 6: Issue 2
Open access
Qi Che Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Qi Che in
Google Scholar
PubMed Close
,
Xirong Xiao Department of Obstetrics, Obstetrics and Gynecology Hospital, Fudan University, Shanghai, China

Search for other papers by Xirong Xiao in
Google Scholar
PubMed Close
,
Jun Xu Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Jun Xu in
Google Scholar
PubMed Close
,
Miao Liu Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Miao Liu in
Google Scholar
PubMed Close
,
Yongning Lu Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Yongning Lu in
Google Scholar
PubMed Close
,
Suying Liu Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Suying Liu in
Google Scholar
PubMed Close
, and
Xi Dong Reproductive Medicine Center, Zhongshan Hospital, Fudan University, Shanghai, China

Search for other papers by Xi Dong in
Google Scholar
PubMed Close

into two distinct types: Type I is estrogen-dependent and derived from endometrial hyperplasia owing to overexposure of estrogen, which occurs more frequently in young women and is related to obesity, early age at menarche, nulliparity, late

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0258
Volume/Issue:
Volume 8: Issue 7
Open access
Shuang Ye Department of Physiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China

Search for other papers by Shuang Ye in
Google Scholar
PubMed Close
,
Yuanyuan Xu Department of Physiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China

Search for other papers by Yuanyuan Xu in
Google Scholar
PubMed Close
,
Jiehao Li Department of Physiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China

Search for other papers by Jiehao Li in
Google Scholar
PubMed Close
,
Shuhui Zheng Research Center for Translational Medicine, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China

Search for other papers by Shuhui Zheng in
Google Scholar
PubMed Close
,
Peng Sun Department of Pathology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China

Search for other papers by Peng Sun in
Google Scholar
PubMed Close
, and
Tinghuai Wang Department of Physiology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China

Search for other papers by Tinghuai Wang in
Google Scholar
PubMed Close

Background Triple-negative breast cancer (TNBC) is negative for estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth receptor 2 (HER-2), and accounts for 15–20% of all breast cancers ( 1 ). Due to this lack of the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0164
Volume/Issue:
Volume 8: Issue 6
Open access
Jordyn Silverstein Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA

Search for other papers by Jordyn Silverstein in
Google Scholar
PubMed Close
,
Wesley Kidder Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA

Search for other papers by Wesley Kidder in
Google Scholar
PubMed Close
,
Susan Fisher Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California, USA

Search for other papers by Susan Fisher in
Google Scholar
PubMed Close
,
Thomas A Hope Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA

Search for other papers by Thomas A Hope in
Google Scholar
PubMed Close
,
Samantha Maisel Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA

Search for other papers by Samantha Maisel in
Google Scholar
PubMed Close
,
Dianna Ng Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Department of Pathology, University of California, San Francisco, California, USA

Search for other papers by Dianna Ng in
Google Scholar
PubMed Close
,
Jessica Van Ziffle Department of Pathology, University of California, San Francisco, California, USA

Search for other papers by Jessica Van Ziffle in
Google Scholar
PubMed Close
,
Chloe E Atreya Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA

Search for other papers by Chloe E Atreya in
Google Scholar
PubMed Close
, and
Katherine Van Loon Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California, USA
Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA

Search for other papers by Katherine Van Loon in
Google Scholar
PubMed Close

studies have sought to evaluate the expression of estrogen receptors (ERs) and progesterone receptors (PRs) in colorectal tumor cells, results have been mixed. Earlier studies reported that 20–90% of CRC tumors express ER and PR ( 19 , 20 , 21 ); however

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0063
Volume/Issue:
Volume 8: Issue 8
Open access
Henryk F Urbanski Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA
Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA
Department of Behavioral Neuroscience, Oregon Health & Science University, Portland, Oregon, USA
Department of Physiology & Pharmacology, Oregon Health & Science University, Portland, Oregon, USA

Search for other papers by Henryk F Urbanski in
Google Scholar
PubMed Close
,
Kevin Mueller Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA

Search for other papers by Kevin Mueller in
Google Scholar
PubMed Close
, and
Cynthia L Bethea Division of Neuroscience, Oregon National Primate Research Center, Beaverton, Oregon, USA
Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, Oregon, USA
Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, Oregon, USA

Search for other papers by Cynthia L Bethea in
Google Scholar
PubMed Close

Introduction Like elderly women, old female rhesus macaques show a marked decline in circulating E concentrations ( 1 ), and several monkey studies have demonstrated the therapeutic potential of E or a selective estrogen receptor modulator

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0108
Volume/Issue:
Volume 6: Issue 6
Open access
Maryam Iravani Department of Women’s and Children’s Health, Karolinska Institutet and Pediatric Endocrinology Unit, Karolinska University Hospital, Solna, Sweden

Search for other papers by Maryam Iravani in
Google Scholar
PubMed Close
,
Marie K Lagerquist Center of Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

Search for other papers by Marie K Lagerquist in
Google Scholar
PubMed Close
,
Elham Karimian Department of Women’s and Children’s Health, Karolinska Institutet and Pediatric Endocrinology Unit, Karolinska University Hospital, Solna, Sweden

Search for other papers by Elham Karimian in
Google Scholar
PubMed Close
,
Andrei S Chagin Department of Physiology and Pharmacology, Karolinska Institutet, Solna, Sweden
Institute for Regenerative Medicine, Sechenov University, Moscow, Russian Federation

Search for other papers by Andrei S Chagin in
Google Scholar
PubMed Close
,
Claes Ohlsson Center of Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

Search for other papers by Claes Ohlsson in
Google Scholar
PubMed Close
, and
Lars Sävendahl Department of Women’s and Children’s Health, Karolinska Institutet and Pediatric Endocrinology Unit, Karolinska University Hospital, Solna, Sweden

Search for other papers by Lars Sävendahl in
Google Scholar
PubMed Close

Introduction Estrogen signaling is mediated via two nuclear and one membranous estrogen receptors (ER). Nuclear receptors ER alpha and beta (ESR1 and ESR2) are activated by the binding of specific ligands, followed by the activation of gene

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0274
Volume/Issue:
Volume 8: Issue 9
Open access
Henrik Ryberg Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden

Search for other papers by Henrik Ryberg in
Google Scholar
PubMed Close
,
Anna-Karin Norlén Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden

Search for other papers by Anna-Karin Norlén in
Google Scholar
PubMed Close
,
Andreas Landin Department of Clinical Chemistry, Sahlgrenska University Hospital, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden

Search for other papers by Andreas Landin in
Google Scholar
PubMed Close
,
Per Johansson Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden

Search for other papers by Per Johansson in
Google Scholar
PubMed Close
,
Zeinab Salman Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden

Search for other papers by Zeinab Salman in
Google Scholar
PubMed Close
,
Anders Wallin Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden

Search for other papers by Anders Wallin in
Google Scholar
PubMed Close
,
Johan Svensson Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
Department of Endocrinology, Skaraborg Central Hospital, Skövde, Sweden

Search for other papers by Johan Svensson in
Google Scholar
PubMed Close
, and
Claes Ohlsson Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden

Search for other papers by Claes Ohlsson in
Google Scholar
PubMed Close

estrogens E1 and E2. In addition, testosterone can be metabolized to the highly potent androgen DHT by 5α-reductase ( 1 , 5 ). However, a more comprehensive description of the complex metabolism of steroids in the brain can be found elsewhere ( 6 ). Sex

Article Type:
Research Article
Collections:
Cardiovascular
DOI:
https://doi.org/10.1530/EC-23-0250
Volume/Issue:
Volume 13: Issue 1
Open access
Clarissa Souza Barthem Laboratório de Adaptações Metabólicas, Programa de Bioquímica e Biofísica Celular, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Clarissa Souza Barthem in
Google Scholar
PubMed Close
,
Camila Lüdke Rossetti Laboratório de Adaptações Metabólicas, Programa de Bioquímica e Biofísica Celular, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
Laboratório de Fisiologia Endócrina Doris Rosenthal, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Camila Lüdke Rossetti in
Google Scholar
PubMed Close
,
Denise P Carvalho Laboratório de Fisiologia Endócrina Doris Rosenthal, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Denise P Carvalho in
Google Scholar
PubMed Close
, and
Wagner Seixas da-Silva Laboratório de Adaptações Metabólicas, Programa de Bioquímica e Biofísica Celular, Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

Search for other papers by Wagner Seixas da-Silva in
Google Scholar
PubMed Close

function that is linked to decreased estradiol production. In this context, estrogens are used for hormone therapy to prevent the development of metabolic disorders ( 2 , 3 ). It has been shown that although estrogen hormone replacement therapy has many

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0470
Volume/Issue:
Volume 8: Issue 12
Open access
Carina Ankarberg-Lindgren Department of Pediatrics, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

Search for other papers by Carina Ankarberg-Lindgren in
Google Scholar
PubMed Close
,
Aneta Gawlik Department of Pediatrics and Pediatric Endocrinology, Medical University of Silesia, School of Medicine, Katowice, Poland

Search for other papers by Aneta Gawlik in
Google Scholar
PubMed Close
,
Berit Kriström Department of Clinical Sciences/Pediatrics, Umeå University, Umeå, Sweden

Search for other papers by Berit Kriström in
Google Scholar
PubMed Close
,
Laura Mazzanti Pediatric Endocrinology and Rare Disease Unit, Department of Medical and Surgical Science, University of Bologna, Bologna, Italy

Search for other papers by Laura Mazzanti in
Google Scholar
PubMed Close
,
Elisabeth J Ruijgrok Department of Pharmacy, Erasmus Medical Center – Sophia Children’s Hospital, University Medical Center Rotterdam, Rotterdam, the Netherlands

Search for other papers by Elisabeth J Ruijgrok in
Google Scholar
PubMed Close
, and
Theo C J Sas Department of Pediatric Endocrinology, Sophia Children’s Hospital, University Medical Center Rotterdam, Rotterdam, the Netherlands
Diabeter, National Diabetes Care and Research Center, Rotterdam, the Netherlands

Search for other papers by Theo C J Sas in
Google Scholar
PubMed Close

Introduction Girls with hypogonadism require estrogen replacement therapy to induce puberty and maintain secondary sex characteristics, as well as to attain peak bone mass. These outcomes are achieved by starting with a low estradiol (E 2

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0025
Volume/Issue:
Volume 8: Issue 4
Open access
Xiaomin Li Department of Breast Surgery, West China Hospital, Sichuan University, Chengdu, China

Search for other papers by Xiaomin Li in
Google Scholar
PubMed Close
,
Ling Fang Department of Breast Surgery, Cheng Du Shang Jin Nan Fu Hospital, West China Hospital, Sichuan University, Chengdu, China

Search for other papers by Ling Fang in
Google Scholar
PubMed Close
,
Hongjiang Li Department of Breast Surgery, West China Hospital, Sichuan University, Chengdu, China

Search for other papers by Hongjiang Li in
Google Scholar
PubMed Close
, and
Xiaoqin Yang Department of Breast Surgery, West China Hospital, Sichuan University, Chengdu, China

Search for other papers by Xiaoqin Yang in
Google Scholar
PubMed Close

, has gradually increased recently ( 1 , 2 ). In patients with breast cancer, abnormalities occur in estrogen metabolism, in particular in the level of estrogen and their metabolites. Hydroxylation of the carbon atoms at positions 2, 4, and 16 of the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0226
Volume/Issue:
Volume 10: Issue 12
Open access