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Bilal B Mughal, Jean-Baptiste Fini and Barbara A Demeneix

chemicals in the maternal and fetal environment. Endocrine-disrupting compounds (EDCs) are xenobiotics that modulate hormonal homeostasis thereby inducing adverse effects ( 8 ). Numerous EDCs identified to date contain a halogen group substitution with

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M Axelstad, U Hass, M Scholze, S Christiansen, A Kortenkamp and J Boberg

certain endocrine-disrupting chemicals (EDCs). Numerous EDCs are present in our environment, and EDCs are suspected of playing a role in testicular dysgenesis syndrome (TDS) in humans. This syndrome encompasses a range of male disorders, presumed to have

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André Marques-Pinto and Davide Carvalho

) and ethinyl oestradiol (EE) (20) , as well as non-steroidal anti-inflammatory drugs (NSAID) and acetaminophen (21) . Natural chemicals such as genistein, a phytoestrogen (22) and heavy metals (23) can also have endocrine-disruptive effects

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M Krause, H Frederiksen, K Sundberg, F S Jørgensen, L N Jensen, P Nørgaard, C Jørgensen, P Ertberg, J H Petersen, U Feldt-Rasmussen, A Juul, K T Drzewiecki, N E Skakkebaek and A M Andersson

prevalent human exposure to UV filters is of concern as several of these chemicals have endocrine-disrupting properties demonstrated in in vitro animal and human studies ( 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 ). We recently investigated the

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Shane M Regnier, Andrew G Kirkley, Daniel Ruiz, Wakanene Kamau, Qian Wu, Kurunthachalam Kannan and Robert M Sargis

in a diet enriched in saturated and trans fats as well as simple carbohydrates that promote the development of obesity and diabetes ( 7 , 8 ). Recently, exposures to endocrine-disrupting chemicals (EDCs) have been implicated as novel metabolic

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Josef Köhrle

) Endocrinology of the Nervous System and Behaviour; and (3) Endocrine-Disrupting Chemicals. The journal will now contain these three independent sections aiming to provide a home for the excellent work published in these fields. These sections will be championed

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A Rehfeld, D L Egeberg, K Almstrup, J H Petersen, S Dissing and N E Skakkebæk

Introduction Human male infertility is a common problem worldwide ( 1 ). The causes are in many cases unknown, but exposure to endocrine disrupting chemicals (EDCs) has been suspected to be involved ( 2 , 3 ). Sperm cell dysfunction is a

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Kylie D Rock, Brian Horman, Allison L Phillips, Susan L McRitchie, Scott Watson, Jocelin Deese-Spruill, Dereje Jima, Susan Sumner, Heather M Stapleton and Heather B Patisaul

similarities with known neurotoxicants and endocrine-disrupting chemicals (EDCs), including PBDEs ( 9 ) and organophosphate pesticides ( 10 ), have raised concerns regarding possible health impacts, especially on the developing brain. Because we have found

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Amalie Carlsson, Kaspar Sørensen, Anna-Maria Andersson, Hanne Frederiksen and Anders Juul

Introduction Concerns have been raised that man-made chemicals such as phthalates and bisphenol A (BPA) may have endocrine properties in humans. These potential endocrine disruptive chemicals (EDCs) are widely used in modern societies, and the

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Frederic Schrøder Arendrup, Severine Mazaud-Guittot, Bernard Jégou and David Møbjerg Kristensen

remains that the rodents as models comes with intrinsic limitations due to species-specific responses and phenotype and that the effects seen might not necessary be transferable to humans. It has been shown that certain endocrine disruptive chemicals can