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Yao Chen and Shu-ying Fang

indicated that polymorphisms in these cytokines genes may contribute to the risk of PCOS. Conclusions PCOS is a common endocrine disorder among women of reproductive aged. Many risk factors affect the occurrence and development of PCOS, including

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Tsuneo Ogawa and Adolfo J de Bold

-mammalian vertebrates was subsequently demonstrated corresponding with the morphological distribution of atrial specific-like granules in various species (16) . These early findings provided the basis to establish the heart as an endocrine organ. Following the

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André Marques-Pinto and Davide Carvalho

able to disrupt the closed feedback loops of the hormonal and homeostatic systems, thus being named endocrine disruptors (EDs) (7) . The group of known ED is extremely heterogeneous. It embraces ubiquitous synthetic substances used as industrial

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C E Higham, A Olsson-Brown, P Carroll, T Cooksley, J Larkin, P Lorigan, D Morganstein, P J Trainer and the Society for Endocrinology Clinical Committee

expert consensus between endocrinologists, oncologists and an acute physician and is designed to aid the early phase of care. This document therefore covers: Endocrine assessment (first 24 h) of patients treated with CPI’s who present life

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J Brossaud, V Pallet and J-B Corcuff

, it may be metabolised in the organism according to its needs, and it acts on nuclear receptors to modify gene transcription. Conversely, it is not regulated by a specific endocrine system (such as the calcium-PTH duet for vitamin D) and thus less

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Veronica Kieffer, Kate Davies, Christine Gibson, Morag Middleton, Jean Munday, Shashana Shalet, Lisa Shepherd and Phillip Yeoh

‘being able to demonstrate that the knowledge, values and skills learned can be integrated into practice’ (2) . Adult endocrine nursing is highly specialised and, in recent years, nurses have expanded their roles according to local need. The Society for

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Jana Ernst, Urszula Grabiec, Kathrin Falk, Faramarz Dehghani and Kristina Schaedlich

was found for an adverse impact on human health due to environmental agents, such as phthalates ( 6 ). Di-(2-ethylhexyl)-phthalate (DEHP) has belonged to the most abundant phthalates in industry and consumer goods for many years acting as an endocrine

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Anita Hokken-Koelega, Aart-Jan van der Lely, Berthold Hauffa, Gabriele Häusler, Gudmundur Johannsson, Mohamad Maghnie, Jesús Argente, Jean DeSchepper, Helena Gleeson, John W Gregory, Charlotte Höybye, Fahrettin Keleştimur, Anton Luger, Hermann L Müller, Sebastian Neggers, Vera Popovic-Brkic, Eleonora Porcu, Lars Sävendahl, Stephen Shalet, Bessie Spiliotis and Maithé Tauber

time when patients want most to fit in with their peers, endocrine disorders that are not optimally managed may render patients with short stature, stunted puberty and sexual maturation, morbid obesity, and metabolic abnormalities. Paediatric and

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M Axelstad, U Hass, M Scholze, S Christiansen, A Kortenkamp and J Boberg

certain endocrine-disrupting chemicals (EDCs). Numerous EDCs are present in our environment, and EDCs are suspected of playing a role in testicular dysgenesis syndrome (TDS) in humans. This syndrome encompasses a range of male disorders, presumed to have

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Ruth Therese Casey, Deborah Saunders, Benjamin George Challis, Deborah Pitfield, Heok Cheow, Ashley Shaw and Helen Lisa Simpson

Introduction Multiple endocrine neoplasia type 1 (MEN1) is a hereditary endocrine neoplasia syndrome characterised by autosomal dominant inheritance of mutations in MENIN , a tumour suppressor gene. Patients with MEN1 typically develop